Conserved Protein Domain Family
TFIIIC_delta

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pfam12657: TFIIIC_delta 
Transcription factor IIIC subunit delta N-term
In humans there are six subunits of transcription factor IIIC, and this one is the 90 kDa subunit; whereas in fungi the complex resolves into nine different subunits and this is No. 9 in yeasts. The whole subunit is involved in RNA polymerase III-mediated transcription. It is possible that this N-terminal domain interacts with TFIIIC subunit 8.
Statistics
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PSSM-Id: 338437
View PSSM: pfam12657
Aligned: 43 rows
Threshold Bit Score: 81.2719
Threshold Setting Gi: 758211810
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0CZF5        12 SCYNALSCSADGELALAAGEFVQIASPKNA----P----EG------NNSTSQtagtSWQLSRFRANT------FTVTEW 71  Aspergillus ter...
XP_004075073  51 SGQQPLAWSPDHRLSVCTASSLSVMEQLCD----VhsnkQHlmllrtSIPVPAep--vKMRVGPSAELaeamkkFSTHPD 124 Japanese medaka
XP_003425560  16 TRSFACKWSEDNRLSIVTEKGVQIIEIVPSatqaS----PIlhlarsFFNPPEam-pCAQYEK-------------YVLS 77  jewel wasp
XP_012059392  16 VNPFAIQWSPDNHISIITEKGVHVLELQPS----PmspnPFfkfsrsFIYHSDtlpaYAFK--------------SEVDS 77  Atta cephalotes
XP_011169866  16 TGPFATQWSPDNQISIITEKGVHVFELIPS----PmssnPAfkfarsFIYSSDtlpaCTFI--------------DEAGS 77  red fire ant
EFN61867      16 TIPFATQWSPDNQISIITDKGVHVFELQPS----PmspnSTikfarsFIYPPEnlpaCSFA--------------NKIDS 77  Florida carpent...
EFN83604      16 TIPFAVQWSPDNQISLITEGGVH--ELQPS----PmspnPIvkftrsFVNATDilpaCAFE--------------NEIES 75  Jerdon's jumpin...
XP_001120537  16 iSKFAVQWSMDNNISILTEKGIHIFELIPS----PispsSTikfsrsFIYTPStfptEIIS--------------NRIES 77  honey bee
XP_003978428  51 SGLQPLVWSEDHRLAVCTSGSLSVMELVCD----VnnsnLDltlhrtSIAVPTeahrFQ--GGPAAEFaeavekFSTHPD 124 torafugu
XP_003440279  43 SGLQPLSWSQDHRLAVCTSSSLAVMELVCD----VhsnkQDltlhrtSIPVPAeeykLR--VGPSVELseamvkFATHPD 116 Nile tilapia
Q0CZF5        72 PTILPRPREYFSVGAEQSN-----------SI-------VADLAWSSPGLGKHRRSILAVLTSNLLLSFYENSGsQGKYA 133 Aspergillus ter...
XP_004075073 125 LTLRQAFLTDRVIHPSVGSh----------KG-------IKYASWSPLGCDATGRCLLACLTLENRLTIHHNSk-RLEWN 186 Japanese medaka
XP_003425560  78 NIFEWPKEEIYSYFLQDALtp-------tfPKalpatadIVDVFWSPCRLLHPLECLLAVVTTTGAIQLVAQIDrT--WI 148 jewel wasp
XP_012059392  78 SIWDMIREEIYSLLMDDVItpkldgvidkfPK-------IIKVSWSPKNLISPSQCILAILNSAGAVELLhk--vSNNWY 148 Atta cephalotes
XP_011169866  78 LIWNLKREEIYSLLMDDIVtpkldgvidksPR-------IVKAAWSPKNLISPSQCVLAILNSAGAVDLLhk--vSNNWY 148 red fire ant
EFN61867      78 LIWNLDRENIYSILMEETItpiidgvndmnHR-------IVNIMWSPKNLISPSQCVLAILTTAGTVELLhk--vFNVWY 148 Florida carpent...
EFN83604      76 MVWKLERKEVYSLLMEEAItpklenvndtvLR-------IIKVEWSPKNLIYPSQCILAILTAAGAIELLhk--vSNEWY 146 Jerdon's jumpin...
XP_001120537  78 KIWNMHREELYSFIIEESMtpklsnvkemvPK-------IIDLAWSPKDLIHPSKCLIAILTSAGAVIIAck--iCRDWY 148 honey bee
XP_003978428 125 PYIRQVFLADTVMNPALGGh----------KG-------IKHAAWSPLGCDLNGCCLLACLTLDNRLTIHNsh-kRLEWN 186 torafugu
XP_003440279 117 PTVRQAFLADRVINPSVGVh----------KG-------IKYASWSPLGCDSSGRCLLACLTLDHRLTIHNsh-kRLEWN 178 Nile tilapia
Q0CZF5       134 RVALVNETLRRHF-----------------EPIIPDEGLRAKKSNIRSFAW 167 Aspergillus terreus NIH2624
XP_004075073 187 LLVDLTQKYGELLiergyakk--drpteanLLDFEEFQRRFRMQTPVRMEW 235 Japanese medaka
XP_003425560 149 LIYEFNAVLAENIeediqq------lkcnkKIDSQELKEQLYRLLVTTATW 193 jewel wasp
XP_012059392 149 SICDIFSLRLKIIedeiktg---lnksnfhENQSARIVESIKKLQACSMTW 196 Atta cephalotes
XP_011169866 149 SICDVSSLRLKIVqeeiksslnksnfnkkfSDQSTKIVENIRKLQACSITW 199 red fire ant
EFN61867     149 SICDISSLRLKNMkdniisn---ldkckksKDKYTVIVENMRQLQACAMTW 196 Florida carpenter ant
EFN83604     147 SICDISALRLNIVqktiksslnkcvnspnnVNKYVRITDSMRMLQACSMAW 197 Jerdon's jumping ant
XP_001120537 149 PVYDLSSLRYSIIeqeinee---leenknnSASFETFKIYMKALQASCFTW 196 honey bee
XP_003978428 187 TLVNLSKKYSNRLkeqgyagk-dnkppvanLLDFDELQRRFRMQTPLRMEW 236 torafugu
XP_003440279 179 MLVDLTKKYSERLkernyark-ddklpqtnLQDFDELQRRFRMQTPLRMEW 228 Nile tilapia
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