Conserved Protein Domain Family
CMV_1a

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pfam12467: CMV_1a 
Cucumber mosaic virus 1a protein family
This domain family is found in viruses, and is typically between 156 and 171 amino acids in length. The family is found in association with pfam01443, pfam01660. 1a protein is the major virulence factor of the cucumber mosaic virus (CMV). The Ns strain of CMV causes necrotic lesions to Nicotiana spp. while other strains cause systemic mosaic. The determinant of the pathogenesis of these different strains is the specific amino acid residue at the 461 residue of the 1a protein.
Statistics
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Aligned: 2 rows
Threshold Bit Score: 276.045
Threshold Setting Gi: 311033408
Created: 24-Mar-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9DUT3 429 WvshfFKSLwpSGDLRDLFGR----YFPSLiRYYDKIEFVEKLThceVFV--NELGMTDDKEQRDVVAEAAdvlkntllK 502  Pelargonium zonate s...
P17769 452 W----FAAL--TRPLRVFFSSvvhaLFPTL-RPREEKEFLIKLS---TFVtfNEECSFDGGEEWDVISSAA--------Y 513  Cucumber mosaic viru...
Q9DUT3 503 VAIKMSLDKTFRPAE--EKKEERtttttvTSSAVGDVDERPAGTVSGPTIQAPSVTQENTVTSLS-------EPLdGRLA 573  Pelargonium zonate s...
P17769 514 VATQAVTDGKILAAQkaEKLAEK------LAQPVSEVSDSPETSSQTPDDTADVCGREREVSELDslsaqtrSPI-TRVA 586  Cucumber mosaic viru...
Q9DUT3 574 VRLEAMKEYKRYLLKLQKNTESNL 597  Pelargonium zonate spot virus isolate tomato
P17769 587 ERATAMLEYAAYEKQLHDTTVSNL 610  Cucumber mosaic virus (strain FNY)
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