Conserved Protein Domain Family
P5-ATPase

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pfam12409: P5-ATPase 
P5-type ATPase cation transporter
This domain family is found in eukaryotes, and is typically between 110 and 126 amino acids in length. The family is found in association with pfam00122, pfam00702. P-type ATPases comprise a large superfamily of proteins, present in both prokaryotes and eukaryotes, that transport inorganic cations and other substrates across cell membranes.
Statistics
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PSSM-Id: 338341
View PSSM: pfam12409
Aligned: 144 rows
Threshold Bit Score: 41.7245
Threshold Setting Gi: 74862432
Created: 30-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0UGR0        201 EDLTIVVAGFNTSPVGFAVYSVLCVATLGIAWLLFRWLPRWRVWLTGRSIPLKDCDWVVI--E----NQWGEF-AVQNVD 273  Parastagonosp...
XP_018119093   12 EENEMELFGYKTVRWRQAFCMIGYICSLGFLRILFYWKPEVDVWCQCTPCALEEANVVLL--Rt--tDEFRQY-SKKKVI 86   African clawe...
XP_002117689   42 tENELQCFGYQTDYLKAFLYYLFCLLTLSILWLVGYWRPDWKHKLTHKACPLAKADSVLI--R----DPNNQH-HPVKIE 114  Trichoplax ad...
XP_012818839   17 SENEFQVFGYRTKRWRQALCYVGYVLSLGLIRFLLYWKQEMYVWFVCNPCSLEEADILLL--Rt--tDEQKKC-CMKKVK 91   western clawe...
XP_002588522   18 QDDELECHGFKRDKVKTSVTVVFATCTLGLLFLVFYWKPEWFVWAQFKSCKLVDADVVLLqtT----DDHRTW-SKERVK 92   Florida lancelet
XP_011660791   49 SEDELECYGYKRSIPKTVLSCIVGILTCGLLLLFFRWKPNWKINCLYNRCNLNDAQCILI--KdfykRWHITYvKTEKVE 126  purple sea ur...
XP_001095224   17 EEDELEVFGYRDHSVRKALCLVASVLTCGVLLLLFYWRPQWRVWASCMPCPLREADTVLL--Rt--tDKFQRY-MRKKVF 91   Rhesus monkey
ELK17632       17 EENELEVFGYRTQNLRRALCLTASVLTCGVLLLVFYWRPQWRVWANCTPCPLQEADTVLL--Rt--tDEFQRY-MRKKVI 91   black flying fox
XP_010591292  709 yrrldEVFGYRSHTLRSALCFIASVLTCGVLWLVFFWRPQWRVWTNCIPCPLQEADTVLL--Rt--tDEFQRY-IRKKVI 783  African savan...
OCA34916       12 EDNEMEVFGYRTVRWRRALCIIGYIFSLGFLRALFYWKPEVDIWCQCIPCSLSEADVILL--Kt--tDDHREFlKKKVME 87   western clawe...
Q0UGR0        274 RQIYGR-SLST-------VF-------GDteKSRFQew-------dE----DDDPL-IK---ELRCLDYRYI 315  Parastagonospora nodo...
XP_018119093   87 KM-YPH-------------Ipg---gkPDhyMVANKn--------sI----LNKSL-MKpegKIRYVKVQKI 128  African clawed frog
XP_002117689  115 IFK-DH-PRRTad-------------vEEesSQGSAy--------dF----ITDSS-LPt--KSKFFEFRFV 156  Trichoplax adhaerens
XP_012818839   92 SFHVAN--VSH-------IAym---nnNTaeKKDSKe--------lP----VNTEL------KVRYMHVQKI 133  western clawed frog
XP_002588522   93 YETNDSmPLHTsslearcELse---tsTDssPFSYRqdnalirdtrS----NCQPE-RQ---NLRYFIHHCL 153  Florida lancelet
XP_011660791  127 IPSKKN--IHA-------EF--------TsgMKRVPg--------qM------KPT-ID---TIRYFVFQKM 163  purple sea urchin
XP_001095224   92 CLY-----LST-------LKfpv-skkWEesLVADCh--------sIinqaLIKPE--L---KLRCIQVQKI 137  Rhesus monkey
ELK17632       92 CLY-----LST-------LKclv-nknLEesLVADHh--------sVinhaVLKPE--L---KVRYIQVQKI 137  black flying fox
XP_010591292  784 CLC-----LST-------LKfpisknpGDplVADRHs--------vInk-aILKPE--L---KLRCIQVQKI 829  African savanna elephant
OCA34916       88 ISDYTQ---------------------GSksGHQVTk--------kNsiieKSLMKkTG---KIRYVEAKKI 127  western clawed frog
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