4DLO,4DLQ


Conserved Protein Domain Family
DUF3497
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pfam12003: DUF3497 (this model, PSSM-Id:256791 is obsolete)
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Domain of unknown function (DUF3497)
This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 213 to 257 amino acids in length. This domain is found associated with pfam02793, pfam00002, pfam01825. This domain has a single completely conserved residue W that may be functionally important.
Links
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Statistics
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PSSM-Id: 256791
Aligned: 33 rows
Threshold Bit Score: 131.308
Created: 29-Mar-2013
Updated: 4-Apr-2013
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4DLO_B   92 GQRMLAGDGMSq--VTKTLLDLT--QRkNFYAGDLLMSVEILRNVTDTF--KRASYIPASDGV-------QNFFQIVSNL 158  human
Q8IZF5  490 TKLLQAGQGSPaeeVPQILAQLPgqAAeASSPSDLLTLLSTMKYVAKVVaeARIQLDRRAL---------KNLLIATDKV 560  human
Q4RL73  594 SQTGQSMDGFAe--VISRLRFSS--DEgAKYSGDLLAIMEILKNTTELY--KGNGLKLSNADV-------ENYVQTISNL 660  spotted green puffe...
Q7SY09  171 LERMTNLS------ISERLKEIR------YQTSAALSPVLLISYIEAMVssKLNFGDVSKDSKehvnetiTNLVFSVNNL 238  zebrafish
Q4SDU3   44 LENMRNFTEPQd--LLKEIVKQT--SG-ELSAVEVITYVEALSRSTSILvsTEKDASMEPSSInf---tlTKLVNAANNL 115  spotted green puffe...
Q6P7G8  176 ISQVNTIKEPIa--ILKEIQRNT--AR-ELLPIDVISYVEVLAASSPLLstVNNSVLNKENTTi------ITFVKTVNNF 244  African clawed frog
Q923X1  179 LKRIGPITEQTt--LLQEIYRNS--EA-ELSLMDIVTYIEILTESSSLLghPNSTTSYKDAHFns---tlTEFGETINNF 250  house mouse
Q9HBW9  130 LTKIRSIKEPVa--LLQEVYRNS--VT-DLSPTDIITYIEILAESSSLLgyKNNTISAKDTLSns---tlTEFVKTVNNF 201  human
Q08DX2  130 LTKIRHIEEPVa--LLREVYRNS--LK-DLSPMDIIAYTEVLAESSPLLgyMNSSNSAKDTSSns---tlTEFVKTLNNF 201  cattle
Q2I0B4  234 TIKDQDASGIPe--LLRAMTSDT--RR-PMVAGDLPKLLNILDIVQEVVsrEVWAKSSQKLVN-------QLIVNVIHNT 301  Cooperia oncophora

4DLO_B  159 LDEENKEKWEDAQQIYP--GSIELMQVIEDFIHIVGMGMMDF--QNSYLMTGNVVASIQKLPAASVLTDi-NFPMKgrkg 233  human
Q8IZF5  561 LDMDTRSLWTLAQARKPw-AGSTLLLAVETLACSLCPQD-----HPFAFSLPNVLLQSQLFGPTFPADYsiSFPTR---- 630  human
Q4RL73  661 LREEHHDKWEEAQLGNN---IKEFLQLVEEFVNMIGMQMSGF--QDIYEVTENLVLSIHKRPTTTSSNf--TFPLKgwrg 733  spotted green puffe...
Q7SY09  239 VEKDEKVEWKKINEDLRkyYVTKLLHTAEKETLALSAGYTHA--TQMQVHAGDVEMKLYTFEPRQAQKH----PLS---- 308  zebrafish
Q4SDU3  116 VEKDELAAWNRMKEEHRerTITKLLHTVEESALTLAKNY--KipTELQIKAPDMEMKLYTIDAGQTKAR--VS------- 184  spotted green puffe...
Q6P7G8  245 VEKDKIKVWNNLKDDIRikSITKLMHTTEQAALDMSQNFKRT--TQLSINASDMALRLFTFDSNHMKHT---HPH----- 314  African clawed frog
Q923X1  251 VERSTHKMWDQLPTNHRrlHLTKLMHTAELVTLQIAQNTQKN--SQFDMNSTDLALKVFAFDSTHMKHA---HPH----- 320  house mouse
Q9HBW9  202 VQRDTFVVWDKLSVNHRrtHLTKLMHTVEQATLRISQSFQKT--TEFDTNSTDIALKVFFFDSYNMKHI---HPH----- 271  human
Q08DX2  202 VQKDTFTVWDKLSTNQRitHLTKLIHTAEQATLRISQNFQKT--TQFDTNSSDIALKAFFFDSHHIKy---IHPH----- 271  cattle
Q2I0B4  302 LR--AKEMWQNWPLMKRqtFATRILTCVERAMTSASTTV-HS--SENYVQPLVMAEMSESIRTSSQPSNyfLFPSMal-- 374  Cooperia oncophora

4DLO_B  234 mvdwARNSEDRVVIPKSIFTPVSSkeldeSS--VFVLGAVLYKNLDLILPTLRNYTVInskiivvTIRPEPK--TTDSFL 309  human
Q8IZF5  631 -------PPLQAQIPRHSLAPLVR-----NGt-EISITSLVLRKLDHLLPSNYgqgl-----gdsLYATPGLv-LVISIM 691  human
Q4RL73  734 mldwIRTSEEKISVSRDALSIDQP-----DGsdAFVTGIILYRNLGSILPFQSNNSLLnskvvsvIVKPTPT--LLSSPV 806  spotted green puffe...
Q7SY09  309 ----ANIQGNSISLSTKKARHANN-----NG--STSVVFLIYHSIGDLLKPADDPGVAdys--ryAAAGEi--tVNSPVI 373  zebrafish
Q4SDU3  185 ----ASMAGDHINLSPKLQAAKDR-----NG--SVSVVFVHYDSVGAILEPSSSQGVAgtgeitvNSRVVAAa-VRPADI 252  spotted green puffe...
Q6P7G8  315 ----VFIEGDSIKISPKKKESSLS-----NG--TVIIIFLRYENIGVLLGLNDNAGIKehd------svdQRalVNSPVI 377  African clawed frog
Q923X1  321 ----MNVDGGYVKISPRRKAAHGT-----TG--NVVVAFLCYKSIGPLLSSSDNFLLDtq-----ndNSEGKekVISSVI 384  house mouse
Q9HBW9  272 ----MNMDGDYINIFPKRKAAYDS-----NG--NVAVAFVYYKSIGPLLSSSDNFLLKpqn----ydNSEEEerVISSVI 336  human
Q08DX2  272 ----MNMDGDNIKIFPKRKTAYDS-----NG--SVAVAFLYYKSIGPLFSSSDNLLEPq-----sYDKAEEErrVISSVI 335  cattle
Q2I0B4  375 --waGENNVDSVDVPKEALELTGL------D--RARVYYASFANIGEEMEPPVETLPSsee---qpSGVERRrrVVSRVV 441  Cooperia oncophora

4DLO_B  310 EIELAHL 316  human
Q8IZF5  692 AGDRAFS 698  human
Q4RL73  807 EIEFPHL 813  spotted green pufferfish
Q7SY09  374 AAAISNQ 380  zebrafish
Q4SDU3  253 YQLDHVT 259  spotted green pufferfish
Q6P7G8  378 AAAINSN 384  African clawed frog
Q923X1  385 SASISSN 391  house mouse
Q9HBW9  337 SVSMSSN 343  human
Q08DX2  336 SLSISSN 342  cattle
Q2I0B4  442 AASIVLD 448  Cooperia oncophora
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