Conserved Protein Domain Family
SET_assoc

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pfam11767: SET_assoc 
Histone lysine methyltransferase SET associated
SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein interaction domains. A subset of SET domains have been called PR domains. The SET domain consists of two regions known as N-SET and SET-C. SET-C forms an unusual and conserved knot-like structure of probably functional importance. Additionally to SET-N and SET-C, an insert region (SET-I) and flanking regions of high structural variability form part of the overall structure. This domain is found in fungi associated with SET and N-SET domains.
Statistics
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PSSM-Id: 338100
View PSSM: pfam11767
Aligned: 66 rows
Threshold Bit Score: 68.3154
Threshold Setting Gi: 808362855
Created: 29-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q2GWF3        247 FVGHEHVPVMPTTVAHMKRRLKTYMFEDIRADRTGYYIVFQDSGygraEAERCFRSADRTAFFTYTMVM 315  Chaetomium globosum CBS ...
Q6CEK8        552 FIAGKYLPSEKVFASDIRRILRDFGWFDVLKEGDGFYVFFDNNR----DTVECYEAMNGRKVNGHQMAM 616  Yarrowia lipolytica CLIB122
Q4PB36        780 YVHIPRPKNCDIDVTSVEAQLRSTAPIWVREGQKGFYAAFHTSK----EANQCKVVNETLTIGGYTLQV 844  Ustilago maydis 521
Q9Y7R4        278 lIDDRFVPPDRVYYTDIKHHFRKFLYEKIYMNKDGFYITFNNYR----EASNCYRALDRTYVQNCRIKL 342  Schizosaccharomyces pomb...
XP_002172037  298 FIDDRFVPPDRVLYSDIRHHFRKYYYDRIYMDRRGFYITFSNYE----EARECYYRLDRTYVNDCRIKL 362  Schizosaccharomyces japo...
CCG80850      268 FIPGKVLPLHKVTAQELQIHFSGKRTEDIFTDPYGFYVLFENDE----VATRAHKIMDKSTFLGYRLYM 332  Taphrina deformans PYCC ...
EKC97692      719 FIDIKSLPYGQVRDEHVQNHFRAFKPDAVLHNHTGWYILFGDDQ----TAHRA-KLMDKTAILSHRINV 782  Trichosporon asahii var....
XP_009265892  728 FIDKSSLPVHSVDVVDVRAFFGQFKVSDVLKNDDGWFVLFTKPG----IAGRAMTTSDGKQCSGFTMHL 792  Wallemia ichthyophaga EX...
XP_012187116  786 YIYIPKPTNCGIDAESIETQLSSTEPLWVSEGDKAFYVAFSTTQ----EANKCKRVNETLTIGAYTLQL 850  Pseudozyma hubeiensis SY62
XP_007874671  334 FINEKCLPFSKFSINDLKKHLNKHDWTDICIDKKGFYIIFKDNQ----SAQKCFVTMNQTSIYQYRITM 398  Pneumocystis murina B123
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