2F5T


Conserved Protein Domain Family
Regulator_TrmB

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pfam11495: Regulator_TrmB 
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Archaeal transcriptional regulator TrmB
TrmB is an alpha-glucoside sensing transcriptional regulator. The protein is the transcriptional repressor for gene cluster encoding trehalose/maltose ABC transporter in T.litoralis and P.furiosus. TrmB has lost its DNA binding domain but retained its sugar recognition site. A nonreducing glucosyl residue is shared by all substrates bound to TrmB which suggests that its a common recognition motif.
Statistics
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PSSM-Id: 371562
View PSSM: pfam11495
Aligned: 26 rows
Threshold Bit Score: 193.648
Threshold Setting Gi: 119525614
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2F5T_X          1 AIWRSRSFDEAIEMFRESLYSAKNEVIVVTPSEFFETIREDLIKTLErgvtVSLYIDKi---PDLSEFKGKGNFFVRQFY 77  Thermococcus l...
Q9HKB6        119 ALINAKNIRSVINNSIDLINETEKTLEIETTQELFAYIREPILRKIRegcrVEILFFGtdvdLEKVQNQFTDLDVDVRYV 198 Thermoplasma a...
jgi:Cmaq_0601  95 QIYVSYGIDGLNNGLVEVISNAQVELYGEIPSWILRKNLRLFMDALGrgvrLYLLVYPsiseEDLHPLREYEDAAWIKVN 174 Caldivirga maq...
jgi:Cmaq_1188 115 LLWVTRGIDNVIYNSASLIQEANSELYVSAPPVLLSRLLKYM-SSIDpkvkAYILVYPslndELLNELKGIKSVVEVKVN 193 Caldivirga maq...
Q9HIL5         80 FLSLVEGYDNIIQKMQTMINEAQNEIIISLSQEKFNDLREDLQRASSrkvtVVLLVFTd---GDVAF----DGRALIRKI 152 Thermoplasma a...
Q6KZ13        114 SLWLIKSKTKLKTTILDSIKNAETEIIISASYENLKSLSSYIREAAKngvtVSIVIFNd---SPSAFIDMLSKYSVIRVR 190 Picrophilus to...
Q6KYU4        110 YLWYMDNEALIKEQIKELIINAKSEIICSLKLPMLRYLDRYLINAANrgvsVIIVIFPd---SDRYDITDLLNTTVLKRR 186 Picrophilus to...
Q9HLU1        111 YLWMIKNNFQIREKMKDVINEAENELIASLNYENIRYLKKYFIDAAKrgitVVIVAFPd---AELDFLRTFPEDIVIRIR 187 Thermoplasma a...
jgi:Tpen_1591 118 RVRVIKNKSEAILRARKMLENASYDALVAGPPRLVGEILPHSVGGGAarrlVAVVYYE-----GVEEPLPAEPWLGLRLR 192 Thermofilum pe...
jgi:Tpen_1154 118 GVWTAVGQNAGESLFLSALESARHELLVAGYSKFLRGFLDRLARTdl---aTCLVLYD-----GEDIGSFVNVFDEVRLR 189 Thermofilum pe...
2F5T_X         78 KLNH--LIGMTDGKEVVTIQNatfdsigppSFKSTYPEIIFSQYSLIIEI--------FKESTLEKE--IIGNPKDIRFF 145 Thermococcus l...
Q9HKB6        199 SPGQf-FTVISDEKNSVFMPRsv-----amNTDIERYGYVIRDKDMSWFIthnf-fvgWYRGNRIK---DHSVVAPYTYH 268 Thermoplasma a...
jgi:Cmaq_0601 175 KLGDf-LLLAADLSKGVYASRrs------lTVNEGSHCYIIQDKDIITRFltif-nstWKESEDALYvdPSRGKYPRKFL 246 Caldivirga maq...
jgi:Cmaq_1188 194 RLGPf-YFISPNAESCVFASSrv-----slLREPETYGYVFRDRTMTLQFihgf-fdtWRRAQTVYRrgFKPSDYPLVFN 266 Caldivirga maq...
Q9HIL5        153 NGKPt-EMAISDRKSCVVSVEg--------ERENKEYALYFEEDNFIHVMsyyfnqslWSQAVIIR---DFFIAESIKFC 220 Thermoplasma a...
Q6KZ13        191 DAPPa-EMMLVDRSRAIVDVGs--------MLQNADYSIMLDEDELIHMLtyyffytiWSPSRYIY---DFTRMTSIKLT 258 Picrophilus to...
Q6KYU4        187 PGISp-EIFIVDREESIVKVDd--------ISKKLVYAIDFQEAEMIHILnyyyynivWKPSMYIS---KFMIKNEWRFN 254 Picrophilus to...
Q9HLU1        188 RGSAs-QVMIADRKHGLINVEs--------TEDSEGYALYFDENELIHILnyyfyhtiWGPSDMFH---DFPVRQNIKFS 255 Thermoplasma a...
jgi:Tpen_1591 193 SVGVipL-VIADSARAVIL--------------RESYALEIAEEDLIRTFldfyyhalWRVSSVVKPf-EPVEGFEYTAT 256 Thermofilum pe...
jgi:Tpen_1154 190 PTRAp-QMAIPDFSQVVIVSG---------WESGQVTAYKVTDDNLMRIFavyyldylRGSGKVVAA--KFGQLERRTYH 257 Thermofilum pe...
2F5T_X        146 AMFHAVDFVKNhl-kNRNIYAEITGKNLESGRLETLTGRVVGytLSLREA-VNNIHLETENG-VVKVGGMFAVIEDYEST 222 Thermococcus l...
Q9HKB6        269 SQRILISDLKRifdqKGRVHGVLEGIVRSTGDRFTSEGEISE--INSDTE-IINFVFKTDRG-EYTVGGYDSQIEDIVMK 344 Thermoplasma a...
jgi:Cmaq_0601 247 NIHFALLTLEAllthGYNPVVSVKGILLKNNEPIEVRGVVSS--VNMLNR-VSNIVVRSNGN-QYTIGGYDAELEDIEAQ 322 Caldivirga maq...
jgi:Cmaq_1188 267 SHRFATWEILKakesKLSIEVRVKGYLTSSNEEVDVTGIPLN--VTIDSDiVNFELLPSNGNkALLIGGTNALIEDIESE 344 Caldivirga maq...
Q9HIL5        221 NIWITCDAIDFllsrNMRVFAEVEGFY--HDDRRTWKGEILK--TEKIPFvRNTFYINVGDR-TYSVGGKTATLEDIKMI 295 Thermoplasma a...
Q6KZ13        259 TSWLACEAIENlkesGFKIMADLKGIL--ENRPVELKGEIIG--TKRVMGvRQSFIIKVNDE-EFSVGGKNAKLEDIKMQ 333 Picrophilus to...
Q6KYU4        255 TSWISCEAINTfinnGYKLTGRVIGNT--QNGQIDITGTIKG--TDIIPGyKNSFLIQSEDQ-VFTVGGRLTRIEDIRME 329 Picrophilus to...
Q9HLU1        256 TAWLSCEAIDSffkrSYSVSGIVTGYS--ATGQVKIEGTITG--IDLIPGfKHTFFIKDNER-VYSVGGKTARMEDIKLE 330 Thermoplasma a...
jgi:Tpen_1591 257 SIWLLNEVLKEclgrGLGAEVTVAGVERRTGRSVTLTGRPAEisENGQGV-RVSLVLEVGQR-KITVGGLGARLEDVEGR 334 Thermofilum pe...
jgi:Tpen_1154 258 HMTRALEHINAllgaGRKPVLTVRGRWVATGEEATVRGVPVRlfENSFRS-VGTILLKLEDGrEVSVGGVGAYLEDVEAY 336 Thermofilum pe...
2F5T_X        223 EIKFiM 228 Thermococcus litoralis
Q9HKB6        345 SFTVaS 350 Thermoplasma acidophilum
jgi:Cmaq_0601 323 EVVIeS 328 Caldivirga maquilingensis IC-167
jgi:Cmaq_1188 345 YIEIrL 350 Caldivirga maquilingensis IC-167
Q9HIL5        296 SVLLhP 301 Thermoplasma acidophilum
Q6KZ13        334 SVVIyP 339 Picrophilus torridus
Q6KYU4        330 ELYLkA 335 Picrophilus torridus
Q9HLU1        331 TLTMnV 336 Thermoplasma acidophilum
jgi:Tpen_1591 335 VFRLkV 340 Thermofilum pendens Hrk 5
jgi:Tpen_1154 337 EITVeA 342 Thermofilum pendens Hrk 5
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