Conserved Protein Domain Family
DUF3173

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pfam11372: DUF3173 
Domain of unknown function (DUF3173)
This family of proteins with unknown function appears to be restricted to Firmicutes. These proteins appear to be distantly related to HHH domains and are therefore likely to be DNA-binding. Genomic environment-visualisation confirms the likely function as being DNA-binding, as this short protein lies very closely between an integrase and a replication protein (http://www.microbesonline.org/).
Statistics
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PSSM-Id: 371495
View PSSM: pfam11372
Aligned: 18 rows
Threshold Bit Score: 80.7249
Threshold Setting Gi: 388533145
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8DZ69                    3 TATYKDLMNLGFPEHTSRDIIREAKKIAVKKfeearkvdhnavqlSKSPFDNRRLGIAPAEIVEQLIGIPL 73  Streptococcus...
bcmhgsc:HMPREF0351_10713  8 MVNRAILIEMGFKPSQAARMIKESKAYLARIe-------------GIDFYNNRQVGVVPSRVIEHLFHIQV 65  Enterococcus ...
bgi:05SSU0863             6 MIEKSHLIKMGFTKYQATGIIKQVKLNLVNQ--------------GYYLYNNKRLAIVPASAVESLIGVTi 62  Streptococcus...
jgi:Lreu_1608             4 MVNYKDLIRLGFKEHQARDIIHQAKINLVEQ--------------GLPLYNGKRIGVVPVRAVEKIVGFPL 60  Lactobacillus...
Q74LF1                    4 LVDFTDLVNMGYKPSQARTIIRIAKNNMVKA--------------GYGLYNNKRLGIVPVKAVEQITGLSL 60  Lactobacillus...
EQC77722                  3 TINHTELMKLGFPEHTARDIIRQAKLIAVRQfeesralsnnvvelSKSPFDNSRLNLAPTYIVEELLGFKL 73  Streptococcus...
bgi:05SSU0101             4 TVNKNDLVALGFSEGTSKRIIRQGKELLIAR--------------GFRVYQNKRVGTIPASIATELLGFDV 60  Streptococcus...
Q8DX67                    5 VMTNKDLIEMGYCPSTANHIIHQARNLMVER--------------GYTFYDRKRLMVVPRSAVSEVIGLEV 61  Streptococcus...
Q5M297                    5 LISNKELIEMGYRPHTANDIIHQARELLVSR--------------GYTFYNRKRLMVVPKSVVNEILGTEV 61  Streptococcus...
Q832I5                    3 TATRQDIIKLGFSQYYADKIFKECKTLLITK--------------GYSFYKNKKIKRIPVSIIEEVLHISW 59  Enterococcus ...
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