Conserved Protein Domain Family
DUF2975

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pfam11188: DUF2975 
Protein of unknown function (DUF2975)
This family of bacterial proteins have no known function. These proteins are likely to be integral membrane proteins. The proteins contain a highly conserved glutamic acid close to their C-terminus.
Statistics
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Aligned: 79 rows
Threshold Bit Score: 32.9759
Threshold Setting Gi: 117560955
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q93J05          30 TTASDEADRFPPYEPFAVP--------------------------------------YATVAILGVACVQVVLCAVWMLL 71  Streptomyces ...
tigr:AHA_0975   66 maqpALASTAPSIADYPLSlgt--------------------------------rllGTLVMLLPDLVFMLMLWQLLQLF 113 Aeromonas hyd...
jgi:Bacsa_2120  62 VITNETATAINEKDGSTVSilpfismigvp----------------nekadatdsifLSLLDWMVMICCIYAIVQFVKMI 125 Bacteroides s...
jgi:Bache_0974  54 TGYHYTDSLTNIKSGEVLPvryekmrtgfmal-------------dvqriplwvravGCLSGMLLFAYVVYSIGLTRNFL 120 Bacteroides h...
CBK64998        67 RVTGQPETAVEIAAAPGVEikanvrklalvveqnapgtsplglafrsiggsawlyalVMLCPLLYLAIIVLMFVIIHSLR 146 Alistipes sha...
WP_122131667    69 SLAATSDKLFNQKDQEWYPashiktlvwa------------------kskdvgiaryVSFLMLIGLFFIIKAIIQFYKLI 130 Parabacteroid...
WP_118423677    86 ygqmivsvntqpsvlSRVI--------------------------------------SLLILIVNYVAIIWAVVLFIRLI 127 Bacteroides i...
CDF21679        79 fshpaCDSLYNRATGSKVAvrvqqigtai-------------------rissaayytQLVINGLAALLALYGLYCLVRMY 139 Prevotella sp...
CDB10074        74 KGEFFTDSVRNEKTGQYVPmaysnlmvsvp-----------------vetpvwqrvaSTLMGFLVLVASIWALVLFIRIV 136 Bacteroides s...
WP_117911316    58 nlisTSDSIYNEMTGKNVPiwqiqsmvtvd-----------------tdapgwlaliNTLLSFILIIFGIKAVLQFIKFI 120 Bacteroides
Q93J05          72 DMVERDAVFSRRAFRWVDTVIGATVVA-TLLA-F-GVAVHLAVAEI---PS--PdddgMQVLGALGAAVAcvgvGAALAM 143 Streptomyces ...
tigr:AHA_0975  114 RGYRQAMLFTFSQIRRYQLIGLLLCVS------F-VTKIITTPLLDlvlTL--PgpelHGQINIGSSDFQ----LLLAGL 180 Aeromonas hyd...
jgi:Bacsa_2120 126 RNIHRNIIFDWANVKRLRRLGFSLILSfCCSL-V-TFAINNHLVSQaisLK--D----CDFSIAFQFSDP----TLLIGF 193 Bacteroides s...
jgi:Bache_0974 121 RNVRERRVFTFENVRLLHRLGLVLVGVwFFSF-L-FAYMDYWGTSSlidFE--N----YRLEFNGISSLL----YLMAGA 188 Bacteroides h...
CBK64998       147 RSIREERTLDKRNVWYLRAIGMLTIVTeLISD-T-VDWVMNSRAAEllaGS--G----YTVDAGFHVSYA----MIIMGI 214 Alistipes sha...
WP_122131667   131 NAINHEVIFDWMNVRRLNRIGRNLLIS-FILTqV-YMITNYWEATRlfeLE--G----YEHNFWCDFQPM----TLIMGL 198 Parabacteroid...
WP_118423677   128 VSINKSDIFNWKNVRRLRRLGVLLIIG-FVCT-FlLAFLSFHNVEKv--FSvtG----YSLSMADMVHIT----SLVLGI 195 Bacteroides i...
CDF21679       140 LSLCKGEVLTRLNATRLRKFVYFFTLFnVVLE-V-ERVIALMQVRGqllLD--G------LRLNEGLTRT----DWTCLL 205 Prevotella sp...
CDB10074       137 VSVNRSDIFNWSNVRRLRRLGVLLIVVfVCVL-L-PEYMALCNLREvfsLE--S----YELILSDSVKVT----NLLLGL 204 Bacteroides s...
WP_117911316   121 RNINRSDIFCWANVKLLRKLGTSLLITfAATL-T-STYMHTWQLSQvlkIP--G----YSYNWLNPFSHS----SLLLGV 188 Bacteroides
Q93J05         144 LVVVMRGLLGKATALRSELAEVV 166 Streptomyces coelicolor
tigr:AHA_0975  181 IVSALALVMREAKRLADEQQLTV 203 Aeromonas hydrophila subsp. hydrophila ATCC 7966
jgi:Bacsa_2120 194 TALLFAEIFAIGLKMKEENDLTI 216 Bacteroides salanitronis DSM 18170
jgi:Bache_0974 189 FSLLGAEVFHIGLKMKEEQELTI 211 Bacteroides helcogenes P 36-108
CBK64998       215 LILFAAEVFAIGQNLSEEQKLTI 237 Alistipes shahii WAL 8301
WP_122131667   199 IALLVGRIFAIGLQMKEEQDLTI 221 Parabacteroides merdae
WP_118423677   196 SALIVAEVFAIGLKMKEEQDLTI 218 Bacteroides intestinalis
CDF21679       206 MLIFLTEVFALAVKLKEEQELTI 228 Prevotella sp. CAG:617
CDB10074       205 ISLIVAEIFAIGLKMKEEQDLTI 227 Bacteroides sp. CAG:633
WP_117911316   189 LAFVIAEVFAIGLKMKEEQDLTI 211 Bacteroides
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