Conserved Protein Domain Family
Kdo_hydroxy

?
pfam11004: Kdo_hydroxy 
3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase
This is a family of 3-deoxy-D-manno-oct-2-ulosonic acid 3-hydroxylases, which catalyze the conversion of 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) to D-glycero-D-talo-oct-2-ulosonic acid (Ko). It contains a potential iron-binding motif, HXDX(n)H (n>40). Hydroxylation activity is iron-dependent.
Statistics
?
PSSM-Id: 431597
Aligned: 17 rows
Threshold Bit Score: 361.995
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
Q0A4T9             15 EHPGDRLERTLEEGNILLFEPGRLPLpSEEDLHFLR---------SEVGRLIKl-KNISYHPHgDYI--------SG--- 73  Alkalilimn...
bbmufp:Hsero_0474  16 DNPHQEWITALEAGKVLYFPRLGFQL-LESERALLD---------PAVRDPKV--RNISLDAR-GHI--------KG--- 71 
nioo:CFU_0827      24 STPNSAWISALEAGKVLYFPHLSFIF-TADEQRFLT---------PAIRDPKS--RNISLDAN-GKL--------KG--- 79 
Q7NX88              9 kEGDKGLVSRLEAGAVLHVPDFGFTL-SAAEQALLN---------PAIADPKR--KNISLEPNnGAL--------HG--- 65  Chromobact...
Q0WGC8             25 AEDNTGAIEALEQGKVLFLPHLTFEL-SEQEKQLLD---------PTLVDVKR--KNISFKPLeGVL--------TG--- 81  Yersinia p...
Q2YBZ7             30 PELQRAAIDMLEGGGVIYLPKSGFEL-SCHERELISdtanilsrtPDVEDGRP---TIIFDPErGRIkkyhyaqvRGk-m 104 Nitrosospi...
Q603T5             18 AKERADALNEIEQGKILYFPRLGFAI-EEHEKAFLS---------PETVG-KS--KNVSFDAAtGDL--------HG--- 73  Methylococ...
jgi:Acid345_2070   23 ADRSRDWCSELESGKILLFDGVPFDL-PSEDRDFLL---------SQKQAASRfhKNISYRPEkNIL--------RG--- 81 
WP_015897158       19 PEQARDWCAQLESGDILYFPQTPIAL-SPDDIAFLR---------GQQQTDSSlhKNIAYKPSlDKL--------SGfda 80  Acidobacte...
unil:wcw_1297      18 ETIKERSIQKLENGSILLYPHLKFGL-EEQEKEFLT---------PEVLKPGT--KNISYQIQtDSL--------SG--- 74 
Q0A4T9             74 MKNEGDA--GEQVLRILREHSRTVNAFLGRMLPGYATS---WSPRKVNFR--PVQEKGRVIKRHSNNELLHVDAFPAGAT 146 Alkalilimn...
bbmufp:Hsero_0474  72 AAGDAEQ--QLALAAMVGRFREQALGLVHSLLPKYSDA---LRVAPTSYR--PMQVETRAQSWRADDRRMHVDAFPSRPN 144
nioo:CFU_0827      80 ALGDAAD--HAALANMIGRFRAQAQQLIHSLLPAYADSrseLRMAPTSYR--PMQVETRSQSWRADDRRLHVDAFPSRPN 155
Q7NX88             66 VLGGDDA--QRAVRALISRYQHAAADLLARVLPEYQGK---TRAAPTSLR--LVRVEDRKTSWRKDDSRLHVDAFPSRPT 138 Chromobact...
Q0WGC8             82 VTDASK---IALTRQLLDRYYQSCLSLVQQLLPVYTHA---LHSPTNSLRlhPVAAWRDSTSWRKDDSRLHVDAFPSRPN 155 Yersinia p...
Q2YBZ7            105 MRAQVKNtaRPQIEAMMSRYSKWTESVITQLFPSYQGA---LERKRVTYR--PFP--------RNNIQSLHIDSSYGYPT 171 Nitrosospi...
Q603T5             74 IGPAVAD--VEALRSMMARFAGRAAGLVARLLPEYSAA---LVQGRTSFR--PVEAAGRASSWRKDDTRLHVDAFPSSPV 146 Methylococ...
jgi:Acid345_2070   82 IANDSPD--RERMQQVMGRYSREVVNFVMRFLAPYARD---FKLDYASFR--PLEEKSRDLVLHKRNDLLHVDAFPTRPT 154
WP_015897158       81 KTANAEA--VARLQSVMRGYSQSVVRFLTGFLSPYAAQ---WKLDYASFR--PQEEQNRDLPLRRRNDRLHTDAFPTRPT 153 Acidobacte...
unil:wcw_1297      75 LQLSGEA--GERLRQMIKRYAETSRKLIQKVFPTYIDH---IEMGRTSYR--PVEAEGRQTSSRKDDTLLHVDAFPSSPV 147
Q0A4T9            147 HGWRPLRFFTNINPD-EARIWRIAEQFRELYQAYGGAAGIA---PAPSLRQGVAerawsgalrglsalglpqlQVVGDTS 222 Alkalilimn...
bbmufp:Hsero_0474 145 YGERILRVFTNINPDgVPRVWRVGEPFETVARRFLPRAKPYv-rWQASVLKALH-------------------VTKSLRS 204
nioo:CFU_0827     156 YGERILRVFANVNPDgVPRVWRVGEPFEDVAQRFLPRVKAYs-rWQAQVLQALH-------------------VTKSLRS 215
Q7NX88            139 YGERILRVFCNINPAgEPRVWRVGEPFEDMARKMLPRVPVQw-pGSAALLAALK-------------------ITKRKRS 198 Chromobact...
Q0WGC8            156 YGERIIRIFTNINPHgEARSWRVGEDFTQLASRYLPQLDSYs-sLSSWLQHKIG-------------------ITKRPRS 215 Yersinia p...
Q2YBZ7            172 QGRGMLRVFSNINPTdRLRIWQLGEPFEPFVRRFLPAAHPSepsWITSILGRLG-------------------IIDGPKT 232 Nitrosospi...
Q603T5            147 QGRRLLRVFSNVNPEgRPRCWRLGEPFEPMARRFLPSIPAPf-pGSAPLLQWLG-------------------LTKSRRS 206 Methylococ...
jgi:Acid345_2070  155 RGARILRVFTNINPI-VDRVWTTGEPFHVMAPGLARPAGLPh-fANPSLAQRFVfatqra--------ghvigLPFPNRS 224
WP_015897158      154 HGARILRFFNNIHPD-RTRDWVVGDPFAQTVRQFAP----------AQIAPRPGtlvsrsgkalgralglskaLPGLKRT 222 Acidobacte...
unil:wcw_1297     148 RGSRILRVFANINPSqIPRVWKVGEPFEDVIRQMAPRVKKPf-tPIFPLMKWVG-------------------ITKSLRS 207
Q0A4T9            223 PYDRAMRRMHNWMKDSDDYQNDPDRgVQLAFEPFHSWCVFTDLVSHAALAGQHALVATYYVKPEACHLPERSPWQVLEQA 302 Alkalilimn...
bbmufp:Hsero_0474 205 EYDHLMLQLHDGMKGDMQYQQDAQQ-VTMPFAAGSVWICFSDQASHAVMSGQYMMEQTLHLAPERQYDPQSSPLAILTRL 283
nioo:CFU_0827     216 EYDHLMLQLHDAMKSDPEYQKDGPQ-VTQPFAAGSVWVCFSDQTPHAVMAGQYMLEQTLHLPAAKQYDPGASPLAILRRL 294
Q7NX88            199 GYDHIMLHLHDAMKADLEYQKNCPQ-ETVPFAPGGAWICFSDHASHAVMSGQFMLEQTLWLPLEKMDDPAKSPLRQLERL 277 Chromobact...
Q0WGC8            216 HYDHLMLQLHDKMKADLAYQKDGLQ-QAIEFPPGSSWICFSDQTPHAAMGGQFMLEQTLLLPVEGMKSSQRSPLKILEAL 294 Yersinia p...
Q2YBZ7            233 RYDRYIATLRSLGMRDKEYQRTAPR-KIMEFPAGASWIAITDLVLHGAISGQHSLDQTFYLPVEAMKDSSRSSLRILERL 311 Nitrosospi...
Q603T5            207 NYDHYMLQLHDRMKADMAYQAEVDQ-VSFDFPPSTTWLVFTDQASHAVMSGQYLLEQTFYVPVEALRDPATSPLRILERL 285 Methylococ...
jgi:Acid345_2070  225 RYDRFMLHFHDWLKENSNFQQNSPK-VRTDFSPGCSWLVYTDGVPHAVLSGQYVLEQTFIIPQRALVAPERSPLQVLETI 303
WP_015897158      223 PYDDFMMRFHNFLKENETYQQQTAR-YPWQFPAGSSWMVYTDTVPHAVLAGQYALEQTFLVQPEALVRPEVSPLRVLEDI 301 Acidobacte...
unil:wcw_1297     208 PYDHYMLNIHDSMKKDQSYQNTCPQ-QVVQLPAGSTWMVYTDQVPHAVLSGQFVLEQTFYLPVEGMQNQQTSPLRQLESL 286
Q0A4T9            303 GQA 305 Alkalilimnicola ehrlichii MLHE-1
bbmufp:Hsero_0474 284 VGH 286
nioo:CFU_0827     295 TGR 297
Q7NX88            278 TGR 280 Chromobacterium violaceum
Q0WGC8            295 TQK 297 Yersinia pestis
Q2YBZ7            312 AGK 314 Nitrosospira multiformis ATCC 25196
Q603T5            286 TGR 288 Methylococcus capsulatus
jgi:Acid345_2070  304 ANT 306
WP_015897158      302 AGA 304 Acidobacterium capsulatum
unil:wcw_1297     287 LNQ 289
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap