Conserved Protein Domain Family
zf-4CXXC_R1

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pfam10497: zf-4CXXC_R1 
Zinc-finger domain of monoamine-oxidase A repressor R1
R1 is a transcription factor repressor that inhibits monoamine oxidase A gene expression. This domain is a four-CXXC zinc finger putative DNA-binding domain found at the C-terminal end of R1. The domain carries 12 cysteines of which four pairs are of the CXXC type.
Statistics
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PSSM-Id: 313678
View PSSM: pfam10497
Aligned: 62 rows
Threshold Bit Score: 125.034
Threshold Setting Gi: 552849008
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q1PF11        160 FNGKTCHQCRQKTMGHRTQC------------------SECN---------LVQGQFCGDCLFMRYGEHVLEALENPDWI 212  thale cress
XP_002955702  146 liGLTCHFCRQKMLCSEEDCprcstrnsaaqclgkstcSSCK---------SATGIFCRACLWVRYGQVLEEVREDPDWL 216  Volvox carter...
XP_001694908   51 HLGICCHFCRQKKLCGEEDCprcahldgeaecigksmcSRCM---------SSTGMFCRACLDCRYGLELEEVRADPNWI 121  Chlamydomonas...
XP_002318303  159 VFGICCHFCRQKTLCSEEDCkrcsnldpdepcigktdcSFCH---------SPTGVFCRGCLQVRYGEDIEEVRENKKWM 229  black cottonwood
XP_004235804  140 YLGICCHFCRQKKLCGEEDCkrcgdsdmdqpcigktdcSSCH---------SSQGVLCRGCLKVRYGEEMEDVRANKEWI 210  tomato
XP_015630077  169 VLGICCHFCRQKKLCGEEGCkrcgegdlnqpcigktdcSSCH---------SSYGILCRACLKVRYGEDMDEVRKNKNWM 239  Japanese rice
XP_009404136  119 LLGICCHFCRQKKLCGEEDCrrcgdgninqpcigktecSVCH---------SSNGVLCRACLKVRYGEEMEEVRAKKDWM 189  wild Malaysia...
XP_003533320  148 VLGICCHFCRQKKLCGEEDCkrcgnfdvnepclgktdcSVCH---------SSTGVFCRACLKIRYGEEIEEVRKNKEWT 218  soybean
XP_001420168  126 recTTCHFCRQKTTDAKTTC-------------------VCGtwrrapeggRGRGTWCGWCLEMRVGENLDEAMADAEWR 186  Ostreococcus ...
XP_002504705  199 tecTSCHFCRQKTADVKTSC-------------------QCArwrktppggRGRGAWCGWCLEMRMGENIDEALADAEWR 259  Micromonas sp...
Q1PF11        213 CPACRG-----------ICNCS--LCRN-NKGWVPTGPIYRRIAALGYKSVAHYL 253  thale cress
XP_002955702  217 CPHCYEkkhgnwrkhgwFCNSS--ICMR-KEGRLPTGIAFHKAQERGYASVAHML 268  Volvox carteri f. nagariensis
XP_001694908  122 CAHCYEeehgpwekhgwFCNSS--FCMQ-AAGKKETGIAIHDAKRLGYKSVAHWL 173  Chlamydomonas reinhardtii
XP_002318303  230 CPHCVEergt---npywICNSS--FCLR-KRKMAPTGLAIFKARDMGYKSVAHLL 278  black cottonwood
XP_004235804  211 CPHCTEekgi---npywICNSS--LCLK-KRKMAPTGIAIFRAREMGYKSVAHLL 259  tomato
XP_015630077  240 CPHCIEekgt---kkfwICNSS--ICLK-KRKLSPTGIAIYDAREQGYESVAHLL 288  Japanese rice
XP_009404136  190 CPHCIEekgi---npywICNSS--LCLK-KRKMAPTGIAIYQAREQGYRSVAHLL 238  wild Malaysian banana
XP_003533320  219 CPHCIEakgi---nphwICNSS--ICLR-KRKMPPTGIAVYRAREMGYKSVAHLL 267  soybean
XP_001420168  187 CPVCRD-----------ICNCSgaNCLRaKRNLFPTQQLTGEALAYGWPSVAHYL 230  Ostreococcus lucimarinus CCE9901
XP_002504705  260 CPVCRD-----------ICNCSgaNCLRaKRGLFPTQQLTHEAIEHGWQSVAHYL 303  Micromonas sp. RCC299
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