2LXE


Conserved Protein Domain Family
WIYLD
?
pfam10440: WIYLD 
Click on image for an interactive view with Cn3D
Ubiquitin-binding WIYLD domain
This presumed domain has been predicted to contain three alpha helices. The domain was named the WIYLD domain based on the pattern of most conserved residues. It binds ubiquitin. In the Arabidopsis thaliana histone-lysine N-methyltransferase SUVR4, binding of ubiquitin to this domain stimulates enzymatic activity and converts its activity from a strict dimethylase to a di/trimethylase.
Links
?
Statistics
?
PSSM-Id: 431288
Aligned: 28 rows
Threshold Bit Score: 65.3468
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
?
Program:
Drawing:
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
2LXE_A        45 KDEKVLKALERTRQLDIPDEKTMPVLMKLLEEAGGN--WSYIKLDNYTALVDAIYSVEDE 102
XP_006606485  10 GESRMDAALDAMKPYGFPNRLVRTTVNSLLKVYGGNggWFFIEESAYSLLIETLLEKQAN 69 
ERN09744      11 GSRRVDAAIDALLPFGFSKSTITCTVNKLLKVYGGDsgWLFIEEASYRLLIDTILEDQEK 70 
XP_004956318   9 GERRIDAAIDHLAEYGFPKPRIRKIINNLLQLYGRDg-WVFLEEGSYKIVLDTLLEEQEQ 67 
XP_002464252   9 GERRIDAATDHLAQYGFAKPQIRNVIHDLLQVYGREg-WPFLEEGSYSLVRNRLLEEQAQ 67 
XP_015696649  10 GGGRIDAAIDHFTPMGYAKPDIRAVVKQLLKLYG-DdgWPFLEEGAYRVVQEALFEKQER 68 
XP_015696559  38 GERRIDAAIDHFIPMGYATSDIQTVIKQLLEVYG-KdgWRFLEEDSYRVVQEALFEKQEy 96 
XP_003579758   7 RVGRMDAAIDHFTPMGYKETQVRSVVNSLLKVYG-NdgWPLLEGDCYEVVQQELFKQEEE 65 
XP_004956294  14 GDRRIDAAIDHFAAMGYAARDIRDAIADLLKVYGGPsaWPLLEEGSYQVVQDKLFEKEDE 73 
EEF35512      10 GLKRIDAALDALRPMGFSPDLIRKTVQSLLKAYGGDegWPFLEENSYRLVIESILEELEk 69
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap