Conserved Protein Domain Family
Apt1

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pfam10351: Apt1 
Golgi-body localization protein domain
This is the C-terminus of a family of proteins conserved from plants to humans. The plant members are localized to the Golgi proteins and appear to regulate membrane trafficking, as they are required for rapid vesicle accumulation at the tip of the pollen tube. The C-terminus probably contains the Golgi localization signal and it is well-conserved.
Statistics
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PSSM-Id: 337711
View PSSM: pfam10351
Aligned: 160 rows
Threshold Bit Score: 182.739
Threshold Setting Gi: 145347745
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6IMT0       1917 VFMPCDMYFQYTRHKGvTPDLK---------------------------------VKPLKELTFNSRNITASMTSRQFQV 1963 thale cress
XP_012549385 1695 IVSRCACEFHYVSLEDapha-------------------------------paaaPHPYDSFSLMHHDLDVCTNSLQYAM 1743 domestic silk...
EFX88195      877 IVSRCNCEILFVSYGQnTLDLDldhdleglmdipp-------ppnddvmdlwaqrEQPVDSFTLTHHDLNICTNSLQYEM 949  common water ...
XP_002413480  883 IISRCGCQFFYASYGE-NIDPDgleevpplcflvs--------qpdeeeeepwgrEAAVDAFTLTHHDLEVCSNPLQYAM 953  black-legged ...
XP_015794775 1714 IISRCSCQFYYVNYSK-DVPSDivdkapplped-----------ddvlnlepwdkEIAVDSFTMNHHDLEIYTNSQQFAM 1781 two-spotted s...
CAG08956     1761 IISRCSCRMHYISYSH-DINPElatqikppelrn----------nhekedllnkqAGAVDTFTLIHHDLEISTNPVQYAM 1829 spotted green...
XP_015222823 1569 IISRCSCRMYYIGYSH-DIDPElatqikppeird----------shekedllkkqDGAVDTFTLIHHELEISTNPVQYAM 1637 spotted gar
XP_012665209 1558 IISRCSCRMYYISYSH-DIDPElatqikppevhe----------nqekedllkkqEGAVDTFTLIHHELEISTNPAQYAM 1626 small-eared g...
XP_018671206 1981 IMSRCTCRMYYVGYEAl-VDSEqtdygqllpstpamedkltsqrnrlagndllgvEKPCNILTIVQPNLEICTNASQFTM 2059 vase tunicate
XP_018671205 2005 imSRCTCRMYYVGYEAl-VDSEqtdygqllpstpamedkltsqrnrlagndllgvEKPCNILTIVQPNLEICTNASQFTM 2083 vase tunicate
Q6IMT0       1964 MTDVLSNLLFARLPKAHndslklsgeeddEVEEEIDEVVpdgIEeVELAKielEAKERDRMMLLDDIRKLtqnesnsgnI 2043 thale cress
XP_012549385 1744 LLDVVNNVVLHVEPERR------------RTLERRARMR---FQlQLHQD---QDPRQQIHKLQTQVRESl-------aR 1798 domestic silk...
EFX88195      950 LLDVINNLLLHVEPHRK------------EASERLQRLR---FQlQLSST---EDQRRPVQQIQNQLRSLi-------sQ 1004 common water ...
XP_002413480  954 VLDLVNNLLLYVEPRRR------------EANERLQRMR---FRlQLSAG---EDHRTPILQLQDQVRSLl-------sM 1008 black-legged ...
XP_015794775 1782 IMDLVNNLLLYVEPHRR------------EAFENLQRMK---FKsVLDPT---ESLRGPILVYQDNLRAMi-------aR 1836 two-spotted s...
CAG08956     1830 ILDIVNNLLLHVERRRK------------EHSEKKQRVR---FQlEISSNp--EEQRSSILHLQEAVRQHl-------aQ 1885 spotted green...
XP_015222823 1638 ILDIVNNLLLHVEPKRK------------VPRHHSLLEI---TFsAIYNFf---------LTLQSSRGSCeg------pQ 1687 spotted gar
XP_012665209 1627 ILDIVNNLLLHVEPKRK------------EHSEKKQRVR---FQlEISSNp--EEQRSSILHLQEAVRQHv-------aQ 1682 small-eared g...
XP_018671206 2060 ILDIVENLLlYVEPVMR------------EHWERVDRMR---FTlRLTSTddvKKHRDTLATMQNRIRLRl-------tN 2117 vase tunicate
XP_018671205 2084 ILDIVENLLLYVEPVMR------------EHWERVDRMR---FTlRLTSTddvKKHRDTLATMQNRIRLRl-------tN 2141 vase tunicate
Q6IMT0       2044 NLEKESDfWM--------------ISGGRpVLVERLRKAYLSVQqsrktayTALRTSVK--------------------- 2088 thale cress
XP_012549385 1799 LRRLEKEyYLknrs-------itgNDPVAvAELKSLDDQVNECKecvwslgEELEAMVR--------------------- 1850 domestic silk...
EFX88195     1005 LRRLEKDtFMlqral-----aedpSNAQFiAEFDSLERKVYECKeqlnaanEELAMMVS--------------------- 1058 common water ...
XP_002413480 1009 QRHLEREaYQvqrsl-----nddpGNPDLeADLAHLEHEIHECKeklsassKELAMIIS--------------------- 1062 black-legged ...
XP_015794775 1837 LKQVEKEsYYlqkalldektasgvENGSMtEELAVYERQIMALKekinrtnEELTLMIN--------------------- 1895 two-spotted s...
CAG08956     1886 IRRLEKQiYSniraq-----teeqSSDELmEINSQLQNQLNQEKndmqmksEELNILIRshisthfypaldkikhnsvtk 1960 spotted green...
XP_015222823 1688 TTMLSG--RCrqlsq-----qdevRNDELsDINRKLQDQLNQEKvdmqmksEELNILIR--------------------- 1739 spotted gar
XP_012665209 1683 IRQLEKQmYSimksl-----qddsKNENLlDLNQKLQLQLNQEKanlqlesEELNILIR--------------------- 1736 small-eared g...
XP_018671206 2118 MRQLERQlFRtdrql-----dndpSDDDLyEESIRLREKLAEEKerlneesEELGIIIR--------------------- 2171 vase tunicate
XP_018671205 2142 MRQLERQlFRtdrql-----dndpSDDDLyEESIRLREKLAEEKerlneesEELGIIIR--------------------- 2195 vase tunicate
Q6IMT0       2089 -----NA--AElRLLEk------------DKNKRPssaMRISLQINKVIWSMVLDG--KTFAEVEIDNMIYDFNRDYRDI 2147 thale cress
XP_012549385 1851 -----AAreLRr-----------------EVPAGAaphRYNEICFKSARWRLTDADgqLGIADLLLTNFLYTKTSRSDDS 1908 domestic silk...
EFX88195     1059 -----CLkeAQlTAHQrlq--------aaRQGSNVttvRTSQINFKHAQWRLTEADgqLGIADVVLTNFLYNKLSKSDDA 1125 common water ...
XP_002413480 1063 -----CYreTQvAALKthq-------rasSHDQEVsvvRRAEVCFKHAHWRLTDVDgqLGIADLVLSNFLYSRLTKSNDS 1130 black-legged ...
XP_015794775 1896 -----LFkeSQlTADKsrenss-vsqegeANQELVsvaRRIEICFKQACWKLTETDgqMGLAKVELNNFIYTKVVKSDDS 1969 two-spotted s...
CAG08956     1961 afsvrCFkdFQlQRANkle--------lrKPPEDVsvvRRTEIYFAQARWCLTEEDgqLGIAELELQRFMYSKLNKSDDT 2032 spotted green...
XP_015222823 1740 -----CFkdFQlQRANkle--------lrKPPEDVsvvRRTEIYFAQARWRLTEEDgqLGIAELELQRFMYSKLNKSDDT 1806 spotted gar
XP_012665209 1737 -----CFkdFQlQRANkme--------lrKQQEDVsvvRRTEFYFAQARWRLTEEDgqLGIAELELQRFLYSKVNKSDDT 1803 small-eared g...
XP_018671206 2172 -----CFkeIFlDQKTrssslrpqhpdqvDEEEEAsvvRTTEVTFGEVKWHVTDKDgqLNIAQFEMRDFLYEKVNKSDDS 2246 vase tunicate
XP_018671205 2196 -----CFkeIFlDQKTrssslrpqhpdqvDEEEEAsvvRTTEVTFGEVKWHVTDKDgqLNIAQFEMRDFLYEKVNKSDDS 2270 vase tunicate
Q6IMT0       2148 GIAQFTTRYVVLRNCLPNAKCDTV-----Lsawn--------pppeWGKKVMLQVDARQGAPKDGQAPYELFQVEIYPLK 2214 thale cress
XP_012549385 1909 VEHQLEVGYVSVKNLLPNEPFPEV-----Lvpqeps-----graplA-RRAALRVFCRDRPPVGGIAVKEHFEVNIVPIR 1977 domestic silk...
EFX88195     1126 CEHSLEIGYVSLANLLPNQIYKQV-----Ivpteln-----rnmpvD-RQVAVRMFSRDKAPVGGICIKEIFEVNVVPFT 1194 common water ...
XP_002413480 1131 VEHLLELGNMKVTNLLPNQAYKASdclfhLqph-----------vpLERQRALRIFCRVRAPVGGISVKEHLEVNLVPIT 1199 black-legged ...
XP_015794775 1970 FEHSLELGYIKVSNLIPNQKHPIV-----Lepapak-----phipiDSRR-ALRVYCRESPPQNGIPIKEHFEVNVIPLN 2038 two-spotted s...
CAG08956     2033 AEHLLELGWFTMNNLLPDAAYKVV-----Lrpqs---------ncqSGRQFALRIFSKVRPPVGGISVKEHFEVNVVPLT 2098 spotted green...
XP_015222823 1807 AEHLLELGWFTMNNLLPNAAYKVV-----Lrpqs---------pcqSGRQLALRIFSKVRPPVGGISVKEHFEVNVVPLT 1872 spotted gar
XP_012665209 1804 AEHLLELGWFTMNNLLPNAVYKVV-----Lrpqs---------scqSGRQLALRLFSKVRPPVGGISVKEHFEVNVVPLT 1869 small-eared g...
XP_018671206 2247 VAHCFELAWLRLQNLLPNSLYRDV-----IkprhqaglrshgitagGGRSLILRVLCKVRPPVGGISVKDHVEVNAVPLT 2321 vase tunicate
XP_018671205 2271 VAHCFELAWLRLQNLLPNSLYRDV-----IkprhqaglrshgitagGGRSLILRVLCKVRPPVGGISVKDHVEVNAVPLT 2345 vase tunicate
Q6IMT0       2215 IHLTETMYTMMWEYIFpgeeqhsqrreevwkvsttsgsrrrkgsfaqeaaallaasdlgqgsknqslksstirgsgrelr 2294 thale cress
XP_012549385 1978 IGLTKKFFNTMLKFCFperdpdsideaedeegaprpstglvs-------------------------------------- 2019 domestic silk...
EFX88195     1195 FAMTYQFFKTMMRFCFpekdpetldgegehsessvarkgg---------------------------------------- 1234 common water ...
XP_002413480 1200 IGLTHAFTRRMLRFFFltrdtgqssqtgvkeksedhlee----------------------------------------- 1238 black-legged ...
XP_015794775 2039 LVVTYKFYKCLENFFFnqddnrtiepsysvvsvgavgqtgsavvsvsgkskgadsis----------------------- 2095 two-spotted s...
CAG08956     2099 IQLMYQFFKRMMGFFFpgrnveeeevadeedkfrlvttgipvkarqssed------------------------------ 2148 spotted green...
XP_015222823 1873 IQLMYQFFKRMMGFFFpgrnveeeevgdeedksrlvttgvpavkprqlse------------------------------ 1922 spotted gar
XP_012665209 1870 IQLTHQFFHRMMGFFFpgrsvdddevgdeedksklvttgipvvkprqliat----------------------------- 1920 small-eared g...
XP_018671206 2322 IQLTYQFFKRMMSFFFpdrsmappgaddmddramssvdtrnatllgfagnsamerh------------------------ 2377 vase tunicate
XP_018671205 2346 IQLTYQFFKRMMSFFFpdrsmappgaddmddramssvdtrnatllgfagnsamerh------------------------ 2401 vase tunicate
Q6IMT0       2295 rtssfdrsweetvaesvatelvlssmehqgesskgklkdsktskaggrsvheekkgeKSLEDKKSRPQKIMQFQTIKISQ 2374 thale cress
XP_012549385 2020 -------------------------------tgskklkkkakdsnsnfyvkrdnkdkDDVEKMKERAEKNKLFIYIKIPE 2068 domestic silk...
EFX88195     1235 ----------------------------------gkhfsnvnktkrgkessfyvpieDDVEKMKERAEKNKLFIYIKIPE 1280 common water ...
XP_002413480 1239 ----------------------------------epkpvthtrrarrsqqppastsrDDIEKMKERAEKNQTFLYIKIPE 1284 black-legged ...
XP_015794775 2096 -----------------itgtgkrrakqpkslsngsnslpsssttsstlslakplvpDDVEKMRQRAQRNKTFAYIKITE 2158 two-spotted s...
CAG08956     2149 ------------------------tmgamgpskgvtqglnrtagvrrsfrkppehpvDDIDKMKERAAMNNSFIYIKIPQ 2204 spotted green...
XP_015222823 1923 -----------------------dsvgalgpskgvtqglnrtsgvrrsfrkppehpvDDIDKMKERAAMNNSFIYIKIPQ 1979 spotted gar
XP_012665209 1921 -----------------------ddavplgsgkgvaqgltrssgvrrsfrkspehpvDDIDKMKERAAMNNSFIYIKIPQ 1977 small-eared g...
XP_018671206 2378 -----------------gsvvslparppppspshmstpgtlrrnksstkrstvseavDDVDKMKLRAAKNNTFLYIKITE 2440 vase tunicate
XP_018671205 2402 -----------------gsvvslparppppspshmstpgtlrrnksstkrstvseavDDVDKMKLRAAKNNTFLYIKITE 2464 vase tunicate
Q6IMT0       2375 VELLITYEGSRF----VVNDMKLCMDTFHRVEFSGTWRRLFSRVKKHIIWGVLKSV 2426 thale cress
XP_012549385 2069 VPVRVSYKGSKEknleDVRDLPLVLPTLEYHNVTWTWLDLLLATKNDTRRVILSQA 2124 domestic silkworm
EFX88195     1281 VPVKVSYKGGKEknieDVHEFFLVVPTLEYHNVTWTWLDLFLAMKNDSKRVLLSQA 1336 common water flea
XP_002413480 1285 VPLRLSYKGEKEknleDLNECSLVLPTIELHNRTCTWLDLLMVIKNDARKVLLSQV 1340 black-legged tick
XP_015794775 2159 VPLRVSYKdkn---igNIQDFKFILPTIEYHNQTWEWLDLINAIKRESKHRLLSQA 2211 two-spotted spider mite
CAG08956     2205 VPLCVSYKGEKNs--vDWKDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQM 2258 spotted green pufferfish
XP_015222823 1980 VPLCVSYKGEKSs--vDWKDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQM 2033 spotted gar
XP_012665209 1978 VPLCVSYKGEKNs--vDWGDLNLVLPCLEYHNNTWTWLDFAMAVKRDSRKALVAQV 2031 small-eared galago
XP_018671206 2441 VPLCVSYKGEKEknieDVRDFNVTIPMLEYHSKTWTWHDFAMAVKRDCKKQLVSQL 2496 vase tunicate
XP_018671205 2465 VPLCVSYKGEKEknieDVRDFNVTIPMLEYHSKTWTWHDFAMAVKRDCKKQLVSQL 2520 vase tunicate
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