4LG1,4LEC


Conserved Protein Domain Family
Methyltransf_16

?
pfam10294: Methyltransf_16 
Click on image for an interactive view with Cn3D
Lysine methyltransferase
Methyltrans_16 is a lysine methyltransferase. characterized members of this family are protein methyltransferases targetting Lys residues in specific proteins, including calmodulin, VCP, Kin17 and Hsp70 proteins.
Statistics
?
Aligned: 15 rows
Threshold Bit Score: 184.843
Threshold Setting Gi: 187034321
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
4LG1_A    17 KRDGTVLRLQQYSSG-GVGCVVWDAAIVlskyLETPEFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 83  human
O13926   138 KSPNDGLWFLEQMGN-SIAKHLWDAGVV----FSKKILSDdw-------hyS-FSNRKDINVLELGSGCGIVGISIASKy 204 Schizosaccharomyces...
Q6CCN8   107 KFDSIPLTIKEDTGN-SIARHVWDAGVT----LAHTLTKEriy-----eqiTgKDSSQQVGILELGAGCGIVGLAVEKHl 176 Yarrowia lipolytica
EAW10257 142 PKNQLDLRIWEETGN-SIARHIWDAAIAsviyIQQAISGEpavaapilqdlLqSQRSTPLHALELGSGCGIVGISLAELl 220 Aspergillus clavatu...
Q4WP35   142 pKDQLDLRIWEETGN-SIARHIWDAAIAsviyLEQAIAKTpgsaasllgslLqGQGSAPLHVIELGSGCGIVGIALAELv 220 Aspergillus fumigatus
Q75AY2    31 QLDPP-LKIHEDGGEsGCGGKVWIAGNLlcefILEKSKDGrvl------sqFpGYERQFKNIIELGSGTGLVGLCVGLHg 103 Eremothecium gossypii
CAP26138  14 NNDESELTIFQETVT-DVGGVIWDSALMtihyFFKh-----------------PAKFEGKKVLELGSGTGVCGIALAAL- 74  Caenorhabditis brig...
Q8C436    22 KRDGTVLRLQQYGSG-GVGCVVWDAAIVlskyLETPGFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 88  house mouse
Q9CQL0    25 SFANHTIQIRQDWRQlGVAAVVWDAAVVlsmyLEMg-----------------AVELRGCSAVELGAGTGLVGIVAALL- 86  house mouse
Q5B6H9   137 VNQSVELSIWEETGN-SIARHIWDAAVAsviyLQQMLAGHpgvsnpvlqnaLqTNRSGPLNVIELGSGCGIFGIALAELl 215 Aspergillus nidulans
4LG1_A    84 ------GADVVVTDLEELQDLLKMNINM--Nk-hLVTGSVQAKVLKWGEEIEGf---PSPPDFILMADCIYYEESLEPLL 151 human
O13926   205 -----pRALVSMTDTEDAIEFMEKNVEK--Nk-sAMSNNITSDILVWGHDIPRk--fRRHWDYIVMSDVMYNESSFSDLE 274 Schizosaccharomyces...
Q6CCN8   177 g----gQGSLILSDLEEARECAEESIAL-------NNSSASFMALDWAD---EdvsqLTNLDLIIVADCTYNMDMYETLV 242 Yarrowia lipolytica
EAW10257 221 -----pHCSVTLTDLPEVEEIVTKNIAV--Ah-pAPSSHITFQTLDWDEELPEdlcaGH-VDLVLVSDCTYNADSLPALV 291 Aspergillus clavatu...
Q4WP35   221 -----pHCSVLLTDLDEVEEIVMKNIAVarP---APLSRVRYQPLDWDEKLPGdlcdGH-IDLILVSDCTYNADSLPALV 291 Aspergillus fumigatus
Q75AY2   104 kyngatDTNVYITDIEGLCPLMQKNVELn-----gLDGMVHPRPLFWGEPL-SdeftRQPIDLVLAADCVYLEKAFPLLE 177 Eremothecium gossypii
CAP26138  75 ------GADVIITDLPERIPLLEKNLAAnkH---LTGNRIKVEVLDWMTDKTPdg-----lDLVLAVDCVYYNSTITPLI 140 Caenorhabditis brig...
Q8C436    89 ------GADVIVTDLEELQDLLKMNIDMnkH---LVTGSVQAKVLKWGEDIEDlm-sP---DYILMADCIYYEESLEPLL 155 house mouse
Q9CQL0    87 ------GAQVTITDRKVALEFLKSNVEA--NlppHIQPKAVVKELTWGQnLes--fsPGEFDLILGADVIYLEDTFTDLL 156 house mouse
Q5B6H9   216 -----pQCSVLLTDLPEVEEIITKNIAV--Aq-pAHASKIQYRPLEWGEELPDdlfgAHTIDLILVSDCTYNADSLPALV 287 Aspergillus nidulans
4LG1_A   152 KTLKDISGFETC--IICCYEQRtmgknPEIEKKYFELLQLD 190 human
O13926   275 ASLQELMDKNTK--LYIAYKKR-----HDNEKTFMSNILGW 308 Schizosaccharomyces pombe 972h-
Q6CCN8   243 ACLERLLKANPSakVVIGHKMR-----NEQESEFFEMLEQR 278 Yarrowia lipolytica
EAW10257 292 TVLNRLVQMSPDviVLVALKRR-----HESEEIFFGLMESA 327 Aspergillus clavatus NRRL 1
Q4WP35   292 DVLDRLVQISPGavVLVALKRR-----HDSEEVFFSLMDSv 327 Aspergillus fumigatus
Q75AY2   178 KTLLDLTAGESQplVLMSYKKR-----RKADKKFFIKIKKE 213 Eremothecium gossypii
CAP26138 141 DLLKNCDAKE----IIVVSEERdigeaSVAQKTFFKNITEF 177 Caenorhabditis briggsae
Q8C436   156 KTLKDLSGSETC--IICCYEQRtmgknPEIEKKYFELLQLD 194 house mouse
Q9CQL0   157 QTLGHLCSNNSV--ILLACRIR-----YERDSNFLTMLERQ 190 house mouse
Q5B6H9   288 SVLGRLIELSPHaiVLVALKRR-----HESESVFFDLMESA 323 Aspergillus nidulans
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap