4LG1,4LEC


Conserved Protein Domain Family
Methyltransf_16

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pfam10294: Methyltransf_16 
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Lysine methyltransferase
Methyltrans_16 is a lysine methyltransferase. characterized members of this family are protein methyltransferases targetting Lys residues in specific proteins, including calmodulin, VCP, Kin17 and Hsp70 proteins.
Statistics
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PSSM-Id: 313513
View PSSM: pfam10294
Aligned: 15 rows
Threshold Bit Score: 184.843
Threshold Setting Gi: 187034321
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4LG1_A        17 KRDGTVLRLQQYSSG-GVGCVVWDAAIVlskyLETPEFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 83  human
O13926       138 KSPNDGLWFLEQMGN-SIAKHLWDAGVV----FSKKILSDdw-------hyS-FSNRKDINVLELGSGCGIVGISIASKy 204 Schizosaccharom...
Q6CCN8       107 KFDSIPLTIKEDTGN-SIARHVWDAGVT----LAHTLTKEriy-----eqiTgKDSSQQVGILELGAGCGIVGLAVEKHl 176 Yarrowia lipoly...
Q4WP35       142 pKDQLDLRIWEETGN-SIARHIWDAAIAsviyLEQAIAKTpgsaasllgslLqGQGSAPLHVIELGSGCGIVGIALAELv 220 Aspergillus fum...
Q75AY2        31 QLDPP-LKIHEDGGEsGCGGKVWIAGNLlcefILEKSKDGrvl------sqFpGYERQFKNIIELGSGTGLVGLCVGLHg 103 Eremothecium go...
Q8C436        22 KRDGTVLRLQQYGSG-GVGCVVWDAAIVlskyLETPGFSG-----------DgAHALSRRSVLELGSGTGAVGLMAATL- 88  house mouse
Q9CQL0        25 SFANHTIQIRQDWRQlGVAAVVWDAAVVlsmyLEMg-----------------AVELRGCSAVELGAGTGLVGIVAALL- 86  house mouse
XP_002633495  14 NNDESELTIFQETVT-DVGGVIWDSALMtihyFFKh-----------------PAKFEGKKVLELGSGTGVCGIALAAL- 74  Caenorhabditis ...
XP_001271683 142 PKNQLDLRIWEETGN-SIARHIWDAAIAsviyIQQAISGEpavaapilqdlLqSQRSTPLHALELGSGCGIVGISLAELl 220 Aspergillus cla...
Q5B6H9       137 VNQSVELSIWEETGN-SIARHIWDAAVAsviyLQQMLAGHpgvsnpvlqnaLqTNRSGPLNVIELGSGCGIFGIALAELl 215 Aspergillus nid...
4LG1_A        84 ------GADVVVTDLEELQDLLKMNINM--Nk-hLVTGSVQAKVLKWGEEIEGf---PSPPDFILMADCIYYEESLEPLL 151 human
O13926       205 -----pRALVSMTDTEDAIEFMEKNVEK--Nk-sAMSNNITSDILVWGHDIPRk--fRRHWDYIVMSDVMYNESSFSDLE 274 Schizosaccharom...
Q6CCN8       177 g----gQGSLILSDLEEARECAEESIAL-------NNSSASFMALDWAD---EdvsqLTNLDLIIVADCTYNMDMYETLV 242 Yarrowia lipoly...
Q4WP35       221 -----pHCSVLLTDLDEVEEIVMKNIAVarP---APLSRVRYQPLDWDEKLPGdlcdGH-IDLILVSDCTYNADSLPALV 291 Aspergillus fum...
Q75AY2       104 kyngatDTNVYITDIEGLCPLMQKNVELn-----gLDGMVHPRPLFWGEPL-SdeftRQPIDLVLAADCVYLEKAFPLLE 177 Eremothecium go...
Q8C436        89 ------GADVIVTDLEELQDLLKMNIDMnkH---LVTGSVQAKVLKWGEDIEDlm-sP---DYILMADCIYYEESLEPLL 155 house mouse
Q9CQL0        87 ------GAQVTITDRKVALEFLKSNVEA--NlppHIQPKAVVKELTWGQnLes--fsPGEFDLILGADVIYLEDTFTDLL 156 house mouse
XP_002633495  75 ------GADVIITDLPERIPLLEKNLAAnkH---LTGNRIKVEVLDWMTDKTPdg-----lDLVLAVDCVYYNSTITPLI 140 Caenorhabditis ...
XP_001271683 221 -----pHCSVTLTDLPEVEEIVTKNIAV--Ah-pAPSSHITFQTLDWDEELPEdlcaGH-VDLVLVSDCTYNADSLPALV 291 Aspergillus cla...
Q5B6H9       216 -----pQCSVLLTDLPEVEEIITKNIAV--Aq-pAHASKIQYRPLEWGEELPDdlfgAHTIDLILVSDCTYNADSLPALV 287 Aspergillus nid...
4LG1_A       152 KTLKDISGFETC--IICCYEQRtmgknPEIEKKYFELLQLD 190 human
O13926       275 ASLQELMDKNTK--LYIAYKKR-----HDNEKTFMSNILGW 308 Schizosaccharomyces pombe 972h-
Q6CCN8       243 ACLERLLKANPSakVVIGHKMR-----NEQESEFFEMLEQR 278 Yarrowia lipolytica
Q4WP35       292 DVLDRLVQISPGavVLVALKRR-----HDSEEVFFSLMDSv 327 Aspergillus fumigatus
Q75AY2       178 KTLLDLTAGESQplVLMSYKKR-----RKADKKFFIKIKKE 213 Eremothecium gossypii
Q8C436       156 KTLKDLSGSETC--IICCYEQRtmgknPEIEKKYFELLQLD 194 house mouse
Q9CQL0       157 QTLGHLCSNNSV--ILLACRIR-----YERDSNFLTMLERQ 190 house mouse
XP_002633495 141 DLLKNCDAKE----IIVVSEERdigeaSVAQKTFFKNITEF 177 Caenorhabditis briggsae
XP_001271683 292 TVLNRLVQMSPDviVLVALKRR-----HESEEIFFGLMESA 327 Aspergillus clavatus NRRL 1
Q5B6H9       288 SVLGRLIELSPHaiVLVALKRR-----HESESVFFDLMESA 323 Aspergillus nidulans
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