3JD5


Conserved Protein Domain Family
DAP3

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pfam10236: DAP3 
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Mitochondrial ribosomal death-associated protein 3
This is a family of conserved proteins which were originally described as death-associated-protein-3 (DAP-3). The proteins carry a P-loop DNA-binding motif, and induce apoptosis. DAP3 has been shown to be a pro-apoptotic factor in the mitochondrial matrix and to be crucial for mitochondrial biogenesis and so has also been designated as MRP-S29 (mitochondrial ribosomal protein subunit 29).
Statistics
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Aligned: 26 rows
Threshold Bit Score: 279.561
Threshold Setting Gi: 757943685
Created: 2-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3JD5_g     98 LMVRKPALELLHYLKNT-NFAHPAVRYVLYGEKGTGKTLSLCHIIHFCAKQ-DWLILHIPDAHLWVKNCRDLLQSTy-NK 174 cattle
O59677    170 LLHRKITTELVNVLQRSkDQGTKDGRFLLDGAPGSGRSIALIQAELFALSQpNFIVLPVHNCEGWVNSTSSYGYDE--QL 247 Schizosaccharomyce...
P82922     98 LMVRKPALELLHYLKNT-NFAHPAVRYVLYGEKGTGKTLSLCHIIHFCAKQ-DWLILHIPDAHLWVKNCRDLLQSTy-NK 174 cattle
Q9W253     93 LMVRNPALELLQYIKDG-DLTKPVVRYVLYGENGTGKTLTMAHVLHYGALN-DFLLVHVPWAPNWMKRPKEASNAAg-QE 169 fruit fly
Q171E7     86 LMVREPAVELINYMNAA-DYSKPANRFVLYGKDGVGKSIVLAHLLHYGYNQ-EFVLVHVPWVPNWMKRAKETANSIt-HE 162 yellow fever mosquito
EDO14441  116 SLVREGT---TKKFLDL-LKKSANKKFIVTGEPGVGKTVLLSQVHAFATEA-KSITVNISYPELFLNGRNDFFYDE--NS 188 Vanderwaltozyma po...
Q755C9    113 CYTREATGQLLERLSGT-----EHQRVILTGQPGVGKSTLLAQAQVAAFEK-GSVIINISHPELFLNGRNDFRHDTtgEQ 186 Eremothecium gossypii
Q6CWQ9    111 SLVRDST---TRKLYEA-LRKSENKKLVLTGEPGVGKSTLLAQLHAHALEN-KGLVLTVSNSELLTNGRNDFFLDE---- 181 Kluyveromyces lactis
XP_316867  93 LMVRRPAVEIMEYLQRT-DFARPVNRFVLHGEDGVGKSLVLAHLLHYGFQQ-QYVLIHVPWVPNWMKRAKEIANSAs-HE 169 Anopheles gambiae ...
CAG11844   37 iMVRSPALEVISYLKKT-DNTRPAVRYLFYGLKGSGKTMSLCHVVHFCYTQ-GWLVLHIPDAHIWVKNCKELLPSSy-NR 113 spotted green puff...
3JD5_g    175 QRFDQPLEASIWLKNFKTANE-RFLSQIK--VQDKYVWNk-----------RESTEKGsPLAEVVEQGIMRVRNATDAVG 240 cattle
O59677    248 KLWVQPDLIKGFLTSVMKTNS-DKLKKLK--TFESHELLq-----------NECIPAGtDLLSFLHKLIASSNAPK-SLE 312 Schizosaccharomyce...
P82922    175 QRFDQPLEASIWLKNFKTANE-RFLSQIK--VQDKYVWNk-----------RESTEKGsPLAEVVEQGIMRVRNATDAVG 240 cattle
Q9W253    170 GMIDLPFDAAAWLVHFKTQNG-PLLQRLQlkTSKEYVWSk-----------RESTPAGsSLIELVEHGIARIKYASETTA 237 fruit fly
Q171E7    163 GCLDLPLDGAAWLIHFKNQNS-KLLAKLDlkVSRDYVWTk-----------RETTPAGaPMLELIDHGINRAKFSCDAIA 230 yellow fever mosquito
EDO14441  189 KLYVQPMYLKSFIRKILKGNDkSVLKSIT--LANDYKFPnndskd-vnrkhLTLFGGKnTLYDLLSVKTVSRSRGE-LFQ 264 Vanderwaltozyma po...
Q755C9    187 EQYTQPMYLKKLLTKILKSNKkSVLSSVA--LTQEYKFPvadtresaskrvTRLVPGKtPLYGLLSMKTTPAARGM-LFQ 263 Eremothecium gossypii
Q6CWQ9    182 DRYIQPMYIKNLLTKFVKSNKkELLQSIK--LSKDYKLVhsggkdlsvkrnVNLSAGKsTLYDLLSVKAPSRHRGA-VFD 258 Kluyveromyces lactis
XP_316867 170 GSIDLPLDGAAWLVHFKSQNG-PLIKSLGltVSREYVWTk-----------RETTPAGaPLMELVEHGINRAKFSCDTIA 237 Anopheles gambiae ...
CAG11844  114 ARFDQPLQANEWLRNFKTTNE-KFLSTIK--TKHRYVWTk-----------RESTNEGsTLGELVDQGINRMKSSSDVVA 179 spotted green puff...
3JD5_g    241 IVLKELKRQSSl--gVFRLLVAVDGVNALWGR--TTLKREDKSPITPEELALIYNLRKMV--KNDWQGGAIvltVSQTGS 314 cattle
O59677    313 IFLQELNNNTKsn-sNMKVLLVIDNISILSVV--TKYKDKKNNFLPPKDFYFINLLFKYIsgSLTFNRGTV---LAATSS 386 Schizosaccharomyce...
P82922    241 IVLKELKRQSSl--gVFRLLVAVDGVNALWGR--TTLKREDKSPITPEELALIYNLRKMv--KNDWQGGAIvltVSQTGS 314 cattle
Q9W253    238 ALIAELKQLSTa--gQCKVMVAIDGFNAFFHPv-TRIFSDNKQLVTPDRVTLTQPFLDIt--NYDWTNGVCilsVDKIAM 312 fruit fly
Q171E7    231 ALLGELKQQSTq--gKLKTMVIIDGFNAFFHPq-TRITTENKVRVTPDKVTLTKPFLDIt--RPDWCNGVCilaVDRMAL 305 yellow fever mosquito
EDO14441  265 SIMQELKSQSK-----VPVYFTIDNFSRILVTsdCAYKNVNNKNIRSLDLQIVKTIMDFVsgDSKFKNKNSaivMATSGD 339 Vanderwaltozyma po...
Q755C9    264 AVIDELVAQSA-----VPVYLTVDNFSRILSEplSAYKDTSCRSIHVLKLQLGRIIMNFVsgATKLNHKDSrvvLATSGV 338 Eremothecium gossypii
Q6CWQ9    259 AFIKELTNQTD-----HPVYFTVDNFSHLLTTpfTAYKDTSNKNIHILKFQVGQSIFDLVsgDLQFAAKDScvvLATSGL 333 Kluyveromyces lactis
XP_316867 238 ALVEELKQHASa--gRARAMVVIDGYNAFFQPh-TRLLTEAKARITPDQITLTKPFLSIt--RNDWTNGVCvvtVDQMVK 312 Anopheles gambiae ...
CAG11844  180 AVMKELRLQSGqpesNFRLAVAVDGVNALWGR--STIKKEDKSFVDPEELTLVYNLRKLm--RNDWAGGAIittLSQTGS 255 spotted green puff...
3JD5_g    315 LFKPRKAYLPQELLGKEGFdt---------------lDPFI-------------------PILVSNYNPKEFEGCIQYYL 360 cattle
O59677    387 QPRVSTPSLDIALGVAHR-------------------NPYKssdetil-----dslqsvhILNMEPYTLDESRRMMEYLV 442 Schizosaccharomyce...
P82922    315 LFKPRKAYLPQELLGKEGFdt---------------lDPFI-------------------PILVSNYNPKEFEGCIQYYL 360 cattle
Q9W253    313 TEGHMDSYMPRYLLGKEGFeh---------------lDPFV-------------------PIHVENYTDKEFHSYISYYL 358 fruit fly
Q171E7    306 TEDRMESELPMYQLRREGFeh---------------lDPFV-------------------PIRVDNYSEEEYYSCVQYYL 351 yellow fever mosquito
EDO14441  340 DRTNR--TLPIALGKAQH-------------------DEYIprkqydpefaeilkkgkveEFQVPKLTKEEVKELMSFYL 398 Vanderwaltozyma po...
Q755C9    339 DRETK--TLPTGLGQTPH-------------------DPYAakynydavlaemmlkggvkEFRVEPLSKPEVAELVDFYA 397 Eremothecium gossypii
Q6CWQ9    334 DRTNR--TLSIGLQKLPH-------------------DPYLtryhyeqilaekllkgkvqEFEVTKLNKDEVAKLMEFYQ 392 Kluyveromyces lactis
XP_316867 313 EFKDTAAGRQSSAVAGPAQvqepslallesrecfehlDPFV-------------------PVSVVGYDDAEYYSCIQYYL 373 Anopheles gambiae ...
CAG11844  256 LYTSRAEYLPQELLGEMGFdn---------------mDPFV-------------------PVSVPNYSEKEFESCYLYYT 301 spotted green puff...
3JD5_g    361 ENNWLQHeK-----AHTEEGKKELLFLsNrnpglleRL 393 cattle
O59677    443 SSNVCLE-K-----VDNYLQNHVLS---GgnprkffDA 471 Schizosaccharomyces pombe 972h-
P82922    361 ENNWLQH-Ek----AHTEEGKKELLFLsNrnpglleRL 393 cattle
Q9W253    359 DRHWIN--------KTPQGFEEQLKFMsNknpyslmQL 388 fruit fly
Q171E7    352 NRKWIQ--------TTEQGFDKELEFLsGrnpfelmEL 381 yellow fever mosquito
EDO14441  399 ESDIVLK-KdkdskSLDQLVDEKYFLSgNgnpreliKS 435 Vanderwaltozyma polyspora DSM 70294
Q755C9    398 KAGILSE-KdqenrREGRLVDEKYLLSgNgnlrellKS 434 Eremothecium gossypii
Q6CWQ9    393 KAGIVLD-KdlqnkTFEQLTEEKYFLSgNgnprellKS 429 Kluyveromyces lactis
XP_316867 374 ERKWIQ--------TNEPGFEEELKLLsCqnpyqlmQL 403 Anopheles gambiae str. PEST
CAG11844  302 DRHWLQH-Pq----SLTEDGKKELIFLsNrnpsvfeRL 334 spotted green pufferfish
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