Conserved Protein Domain Family
DUF2353

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pfam09789: DUF2353 
Uncharacterized coiled-coil protein (DUF2353)
Members of this family of uncharacterized proteins have no known function.
Statistics
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PSSM-Id: 313080
View PSSM: pfam09789
Aligned: 19 rows
Threshold Bit Score: 290.362
Threshold Setting Gi: 75018703
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75018703   20 QQKCGAKTDTIVRLGQDLEKSENEKKGLAARVETLERNLERSERELQLVCACQNDM----Kikf-------gtERQDLIE 88
gi 121955360  24 HRKLQSKVEALKIMRNELEKYRSERDQFKLMAETLQMRYSAMKSSLNSPEFQAAGF----G------------HSSAVSL 87
gi 74800415    4 sRKLQSKVEALKIMRYELEKCRTERDQFKLMAETIQLRYSAIKNSLNAPDFQAAGF----G------------NSSAVSL 67
gi 242022737  26 KRQLESKSEALLILNKELAECRSERDQFKLMAEKLQEKCSTLKKNSFKESSL---F----Nd----------nYDEPISP 88
gi 512932892  27 KSKLQSKVDALCIMSKELDKCSMERDKYKVLVEHLKSKKVVSSKIAENNNAYRFTp----------------tNTISNGD 90
gi 675890378  22 KRRLESKCEAVMILSRDLDESRQQRDQLKLMADQLQNRYQMIRRQLAGAKFSSSQFledhSd----------iKQHNVVE 91
gi 357626780  26 KSKLQSKIDALSIMSNELDKCCMERDRYKMLVEQLKCK----KHMQHNNNLDRFAp----------------tNTISGSE 85
gi 964151710  32 HRKLQSKVEALRILRQELEQFRVERDQYKLVAETLQLRYSALKTNNELLAVGGCGAl---------------sENSSLAA 96
gi 156550139  31 KKKLQIKTQALMMLSQELDQCRMQRDRCKLMAEEMQEDLSR-RKQVADQKTVNGYR----NlvelpskantleEDTKIMD 105
gi 749795877  25 KRKLQMKSEALMLLSQELDQCRIQRDQFKLMAEQIQERFLHLKKQMCDTKELNRCY----Nl----------dDDFRTLD 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75018703   89 DIEKYKRENQQLRTDRQELLDQKADLKKDCKTFRqt----iAQFEVEKMGGPVRNSFST------ENDEVSKLEAHEKLQ 158
gi 121955360  88 LVNQTRERNISLSTEVEALRQRVHELEGDIDVLRtkn--fdLQAAFNKMKSTEETKLRDrkgivwDEEKSKLIAQMETLK 165
gi 74800415   68 LVKQTRERNEALTTEVESLKQRLYDLEGDIKVVRarn--veLQDTCGKLRATNESLLSTngdktwQAEKSQLIAQLEQLR 145
gi 242022737  89 TSSDSKDVNRSLKFEVDCLRQKLRDALGDVKALR-------NQLNEQKLMPVGIDSLSLk----hLDKQEALVKQIEAMH 157
gi 512932892  91 MFAQTKDHNNMLKVEVEMLRSKLEEAAGDILVLRk-----qLQNTRPCKGYDNKDICNDtt--ytAVDYERLVNDLEKMK 163
gi 675890378  92 LLGEVKDENKCLKLQLEELRQKLDDANGDIKLLR-------EQIARHRLGCENEGMMESrf--isCDEREQLISRMEKGA 162
gi 357626780  86 ILARTKESNNMLKLEALLKLLSLQ-----CEGPS-------TRTVNPLKAKKFHGHLKPt----lDRKSQALLKLLSPAT 149
gi 964151710  97 LLHETREQNLKLSTEVEALRQRLNELQGDMELLRet----eASNKSRVQAMATENAARNkeevqwRRERANFICHLEGLK 172
gi 156550139 106 LLIEAREQNKCLRLQVDTLRQKYKEAQEDIKALRsrr--meEPKPLSEITPA-------------LHQREEMIEQLEKMN 170
gi 749795877  91 LLTEAREQNKCLRLQVETLRQKLGDAEGDIKALRmnnnrvsVEQQDTQLAPS-------------MHQREEMIEQLEKLN 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75018703  159 AKCK-----GLESDLRSMLGIKEELLMERDEMQRKVARLSNELSYLL------------N--G-------DPRRVAeDLD 212
gi 121955360 166 KKNA-----QLQYDVRSLLDEKEDVVMERDAYKCKAHRLNHELSVML------------K--Gd-----qSQQKIV-DVD 220
gi 74800415  146 KRNA-----QLQYDFRSLLDEKEETVTERDAYKCKAHRLNHELNVAL------------R--Gagg-aggASQTLL-DID 204
gi 242022737 158 KLKN-----QLEIDLQSVIDEKEELITQRDAYKCKVHRLNHEFSVLL------------K--S-------SNHSVI-DID 210
gi 512932892 164 KKYQ-----QIQLDYRATLDEKEELVSDRDYYKNKVQRLNHQISYLLsnrsnlptgegeS--A-------APSPIV-DIE 228
gi 675890378 163 SKMQ-----QLERDMQQLLDEKEELVMERDQFKNKYNNLNLHLNLIL------------RpaG-------CQNKII-DID 217
gi 357626780 150 RWTRtrtyrQIQLDYRTTLDEKEELVSDRDYYKNKVQRL---ISQIF------------N--NsaktnseNSTPFV-DVD 211
gi 964151710 173 KRNA-----QLAYDLKAVIDEKEELITERDAYKCKAHRLNHELFVAL------------R--Ak-----kTHPRLL-DID 227
gi 156550139 171 VKCR-----QLKLDLQSVLDEKQELELERDAFKCKAHRLNHELSQAL-----------------------SASRPV-DVD 221
gi 749795877 158 LKCS-----QLQTDLQTVLDEKHELEMERDAFKCKAHRLNHELSKAL-----------------------NASKPV-DLD 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75018703  213 SLVAENRFLKAKLNTAEEESESIKMTLAKYKQMAeavNVQ-TMvnR-SPKAGEGDDKPsvaVINMKQIRELLASHAIELV 290
gi 121955360 221 GLILENKYQQEKITNLENELELSRQSATKYKNML---DTK-RKk-G-IIKLGTNNNQR---VMSHSQVKDLLERGTVEEL 291
gi 74800415  205 GLILENKYQAEKIANIENELSLARQAASKYKSML---ETN-RKk-G-IIKLGTNNNNKt--IMSHSQVKHLLENGTVDEL 276
gi 242022737 211 SLIMENRFLQEHLQQAQEEINLVNQTSNRYKSLL---EKK-HNk-G-AIKLALENLSGi--SLSPEQVQELFETNSTEQI 282
gi 512932892 229 ALIAENKYLHERITQLQIENELIKRNLSKYKTLL---DNRsRNy-SvHLKKGFAD------VMTQKQVKEFLENNLKSNS 298
gi 675890378 218 ALLAENKFLNEKMKQMEEEKLCALAAVSKYKGIL---GKK-RSk-G-NLELGQARGTGl--VISQKQVHDLLTTSNLTNQ 289
gi 357626780 212 TLLTENKYLHERITQLQVEKEIVKRTLTKYKTLL---DNR-NKseP-YIKKGFAD------VMTQKQVREYLDINSKTGL 280
gi 964151710 228 SVLLENKYLHERVKIQESELELSKQSITKYKTML---DAK-RKk-G-IVKLGGGSTNEe-tILSPRQVKSILESGIDLPQ 300
gi 156550139 222 ALINENRYLQERLQQLLEEKELAQQSVQKYKSML---DSK-RQk-G-VIKLGGKSSVGs--VMNFKQVEQLLQ-QGPNIP 292
gi 749795877 209 ALINENRYLQERLQQLLEEKELTRQSLSKYKSML---DSK-RTk-G-AIKLGANSAVGt--VMTHKQVEQLLQ-ESSYIP 279
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 75018703  291 -------ESDYRAITTILLDLCNDKQMALAHSRRANKVLGMRLHEVESKLAVL 336
gi 121955360 292 plk-aatISELKSLCLALLDNVNDKSLALSHQKKTNKLLAAKITELEQRILAL 343
gi 74800415  277 plk-aatISDLKSLCLALLDNVNDKSLALSHQKKTNKLLATKIAELERHIKTL 328
gi 242022737 283 pnsvaatISDLKFMCLALLEYSNDKILALSHQKRANRILAAQICELEHRVENL 335
gi 512932892 299 kh---nsAAELKSVCLGLFEALNDKSTALQHQRKTNQILASRLTELEKTLEaw 348
gi 675890378 290 tp---qmMQDIHSLASSLLDCLNDKSLALSHQRKTNKILGARVDELENKLKEL 339
gi 357626780 281 kr---gsAQELKRICLGLFEALNDKSIALQHQRKTNQILANRITELEKTLESL 330
gi 964151710 301 kt---etIHDLKSLCLALLDNLNDKNLALSHQKKTNKILAGKMTELEQRWQQL 350
gi 156550139 293 pqksaaaLSELHSLCTALLEALNDKNLALAHQKKANKILAARMCELDRAVqsp 345
gi 749795877 280 pqksaaaVTDLRCLCTALLEALNDKTLALAHQKKANKILALRICELDSAVqsp 332
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