Conserved Protein Domain Family
C_GCAxxG_C_C

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pfam09719: C_GCAxxG_C_C 
Putative redox-active protein (C_GCAxxG_C_C)
This entry represents a putative redox-active protein of about 140 residues, with four perfectly conserved Cys residues. It includes a CGAXXG motif. Most members are found within one or two loci of transporter or oxidoreductase genes. A member from Geobacter sulfurreducens, located in a molybdenum transporter operon, has a TAT (twin-arginine translocation) signal sequence for Sec-independent transport across the plasma membrane, a hallmark of bound prosthetic groups such as FeS clusters.
Statistics
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Aligned: 387 rows
Threshold Bit Score: 36.0346
Threshold Setting Gi: 524097024
Created: 4-Jun-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CBRAS:MROS_0472  80 VEALREKIGDPWTnm--pIEVMLFGRGGGVG-WGTLCGATNGGAALISLVVP--------KADSGKLINELWGWYCTekl 148 Melioribacte...
Q6ARN0           24 VLLALDEMDRENPd----LVRAASGFCNGMGdGTGPCGVYAGANLLLGLYAGkglameqaDGKLALMLEEFAQWFVSrt- 98  Desulfotalea...
CCH49110         24 VLLTLDEMDRENPd----LVRAAAGLCNGLGdCSGPCGVLTGAAMVLGVFGGkgtdleeaEEVLPVMLESLRDWFAErt- 98  Pseudodesulf...
jgi:DND132_0145  24 VIMALDEMDREDPd----LVRAAGGLCNGLGdCSGPCGVLTGSVLALGLYAGkgqdmeepEEVLPVMLESLRDWFTErt- 98  Desulfovibri...
jgi:Desal_0295   23 IILCLDNLQQENPa----LVRAAQGLCMGMGdCAGTCGILSGGLCALGLYAGkgteveaaEDNYPLLVETFREWFKErv- 97  Desulfovibri...
Q30VG0           24 ILLALEGMGRRNPd----LVRAAAGLCHGGSdCDGPCGVLTGGNCLLALYTAkghdndtaDEILPLLLEEYGEWFGQav- 98  Desulfovibri...
Q72BS9           24 VLLSLQGMGLDDPp----LTRAMAGLCNGMGdCSGPCGILSGGACVLALHTAqgfagdtvDERLPLLLEAFRDWFHDat- 98  Desulfovibri...
jgi:Ddes_1819    23 VLLMLQVRDEENPg----LVRAVHGLCHGIGqSDGPCGLLTGGACALALSAGkgaahetpHPMLAPLLNDYATWFYErt- 97  Desulfovibri...
jgi:DvMF_0638    24 VRLLLDVQGRDVPddgrdAVRAAGGLCRGFGlSEGTCGILLGGCMAMGLCAAkghdaeepHEALEAMTTEFAEWFRErt- 102 Desulfovibri...
jgi:Despr_1632   23 IQLTLEDMGEDNIp----LVRAMAGLCEGAG-SGELCGVASAAACIIALYTAkgsvaehpLDCYPLMLAQFMDWFKQga- 96  Desulfobulbu...
CBRAS:MROS_0472 149 psdaanqaavdgkyidkkyndvlpQSvgGSVLCHAS-VsqwcmiakK------KVSDIERkerCARLAGDVAAKTAEI 219 Melioribacter ...
Q6ARN0           99 -----------------------sAH--AGIRCLDI-L--------Dg----sTP--QMNtslCGSLLADAHGRVREI 136 Desulfotalea p...
CCH49110         99 -----------------------aEH--GGTTCGHI-L--------Dg----rCG--QADpvlCGGLLADAHEKVREI 136 Pseudodesulfov...
jgi:DND132_0145  99 -----------------------lEY--GGITCGAI-L--------Dg----gCG--KPHperCGGLVAEANAKVREI 136 Desulfovibrio ...
jgi:Desal_0295   98 ----------------------stEF--GGIKCSDI-L--------Dg----eCG--APRadrCGVLLGEAYAQLVNI 136 Desulfovibrio ...
Q30VG0           99 -----------------------aQY--GGIQCSQI-T--------Gg----qCR--TPDmsrCGTLVAAAYGRLLEI 136 Desulfovibrio ...
Q72BS9           99 -----------------------tPY--GGITCGVI-M--------Gg----dCR--TPDpsrCGVLLAESHQRINAI 136 Desulfovibrio ...
jgi:Ddes_1819    98 -----------------------gPY--GGQSCGQVaA--------GlgalsgVAGEMPNpvaCGDLLADCWGKIMEL 142 Desulfovibrio ...
jgi:DvMF_0638   103 -----------------------aPS--GGISCGAI-L--------Gd----nAGG-RPDfgkCHGLLLEAHGKMFEV 141 Desulfovibrio ...
jgi:Despr_1632   97 -----------------------tAW--GGIRCDDI-V--------A-------YQGGRKpevCGDIMIRARETLLal 133 Desulfobulbus ...
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