4Q47


Conserved Protein Domain Family
RQC

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pfam09382: RQC 
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RQC domain
This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure. The RQC domain, found only in RecQ family enzymes, is a high affinity G4 DNA binding domain.
Statistics
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PSSM-Id: 378173
View PSSM: pfam09382
Aligned: 120 rows
Threshold Bit Score: 64.1001
Threshold Setting Gi: 121976275
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4Q47_A         407 PPRVRDLTREAQMALSATIRTg-NRFGAAHLTDVLLGRETDKVLAqghHQ--LPTFGVGKEHDEKLWRSVLRQLVSLGYL 483  Deinococcus ...
jgi:Paes_0060  408 TREVTDCTREAQMLLSAIARTe-GRFGATHIIDIVMGSKNKKILElghDR--LKTYGVGKEKNKKFWRHLIDELLAQKMI 484  Prosthecochl...
BAF73206       398 QSEKVDITTASRMLLSTILRTe-QKFGLHYVIDVLRGSKEQRVLQnghDT--LSVYGIGEEYSKAQWMTIGDKLLELGAV 474  Sulfurovum s...
Q30P76         397 KEIRENITKEAQMILSAIYKTe-QKFGKNYIIDILRGSKEQKLLAnsaDK--LSVYGIGESRAKRVWYVILERLLELKIV 473  Sulfurimonas...
EGZ76138      1345 sTEMRDFTEIAFAAIEVVKSQ--QPITLGKLCDILMGKRKNe-----hGG--VCHFGIAKGSTQRELQRIVLQLNFHKAL 1415 Neurospora t...
BAF39273       465 TFETIDVTDIARAISRCVHDVn-QHVGSGKIVKVLRGSKAQDLSYl--NPesLPSFGMLDEVPEARIRDVLSQMATDGFL 541  Bifidobacter...
EDL46948       527 TDLGVDLSEELKTLLSCISSLr-GRTGVGVICKVLVKSKEACIVKkgyHN--IKEYGEGAHRSTSWWSAFIKVARNDKFV 603  malaria para...
Q4YR17         564 LDNISDLTKELKILLNCVISLk-GKTGISTICKILIKSSESNIIKkgyHT--IKEYGEGKHKPASWWSAFMKVCRNDQFV 640  Plasmodium b...
Q19546         629 SSSIVDVTTESKWLFQVINEMynGKTGIGKPIEFLRGSSKEDWRIkttSQ--QKLFGIGKHIPDKWWKALAASLRIAGYL 706  Caenorhabdit...
Q17G85         422 QDGNYDFSKDAEHLLKAVEAFg-GGTGLALPIALLRGSKSKKLHSs-yLK--NPLHGIGKTKDDEWWKALAVLLEREGFL 497  yellow fever...
4Q47_A         484 ---SADDH----F---GLRATGKS--RGILK--EGQKLLLRED 512  Deinococcus radiodurans R1
jgi:Paes_0060  485 ---AKAEG----Ly-pTLYLLEQS--VPVLK--GEARLEMVRV 515  Prosthecochloris aestuarii DSM 271
BAF73206       475 ---EIG------Ef-kVYKLTNFG--VEVIK--GAHGIKLKKE 503  Sulfurovum sp. NBC37-1
Q30P76         474 ---YLG------Ef-sVLKLTQEA--AETLR--GKKEIFIRAS 502  Sulfurimonas denitrificans DSM 1251
EGZ76138      1416 g--EDNIMngagMpitYYITGPEA--GAYLY--NGKRLMLPVP 1452 Neurospora tetrasperma FGSC 2509
BAF39273       542 tiaEGRLP--------IVGFGPRA--AETVA--PEFHYDIKKI 572  Bifidobacterium adolescentis ATCC 15703
EDL46948       604 ---KETLVyskdVsylSVGVTPKG--EAFIKdsGQ-KYTVRLP 640  malaria parasite P. vivax
Q4YR17         641 ---EELLNysndMgyiSIGITKKG--EDFIN--SDRKYIIPLP 676  Plasmodium berghei
Q19546         707 gevRLMQM----KfgsCITLSELG--ERWLLtgKEMKIDATPI 743  Caenorhabditis elegans
Q17G85         498 a--KTKVPntfnKfavIYKIGSTPlaKKWLAtpNR-KLLMKPT 537  yellow fever mosquito
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