Conserved Protein Domain Family
Pas_Saposin

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pfam09016: Pas_Saposin 
Pas factor saposin fold
Members of this family adopt a compact structure comprising five alpha helices. Charged and polar residues are exposed mostly on the surface, while most of the hydrophobic residues are buried inside the hydrophobic core of the helical bundle. The precise function of this domain is unknown, but it is has been shown to induce secretion of periplasmic proteins, especially collagenase.
Statistics
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PSSM-Id: 312534
View PSSM: pfam09016
Aligned: 5 rows
Threshold Bit Score: 113.846
Threshold Setting Gi: 490868410
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 81707314   1 MKALIYETLVNLANQDPEQHATIRQNLYEQLDLPFDKQLALYAGALGPASSGKLENHEAISNAVDSVVQLLEIPEH 76
gi 81726196   1 MKTLIYDTLISLASQEPEQHARIRQNLYEQLDLPFDKQLALYSCALGPASSGKLESSQGINNAVDCAVKLLETPER 76
gi 75352762   3 TTSLIYNTLTNLATAEPTQCAQIRQKLYDELNLSFDKKFALYSSVLGPVSAGRIDD---LNDAVNKARAILEDKNY 75
gi 490868410  3 TTTLIYDTLEGLSSAKPQQHAQIRQNLYNQLDLSFEKQLALYSSVLGPASAGRLTD---LDSAVMSARKIVGL-EN 74
gi 503634521  1 MKALIYETLISLANQDPEQHAKIRENLYEQLGLPLDKQLALYSRALGPASSGKLENDQAINNAVESAIKLLETPEH 76
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