1G4F


Conserved Protein Domain Family
Sushi_2

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pfam09014: Sushi_2 
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Beta-2-glycoprotein-1 fifth domain
The fifth domain of beta-2-glycoprotein-1 (b2GP-1) is composed of four well-defined anti-parallel beta-strands and two short alpha-helices, as well as a long highly flexible loop. It plays an important role in the binding of b2GP-1 to negatively charged compounds and subsequent capture for binding of anti-b2GP-1 antibodies.
Statistics
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PSSM-Id: 312533
View PSSM: pfam09014
Aligned: 19 rows
Threshold Bit Score: 133.239
Threshold Setting Gi: 514730579
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1G4F_A         2 KASCKLPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFK-----EHSSlaFW 76
gi 597777038 263 RASCKVNIERGRILYKGQKIWIEDFKPNQVQHSEQVAVYCLDKERDCGFPAETHCIDGQLEIPGCFEepsklKYQL--KA 340
gi 637341966 263 RARCPISAQRSRVIYNGRKLWINEIPAGLVHHGETVKFFCRSQNKTCSFEAESQCFDGVLKTPDCYDeptylQYHL--FP 340
gi 348541779 263 KAPCKIGIDRGRILYKGKKMWIGDFNPNKVLHKDIVSVWCMNNARKCGYSVSTQCIDGRLVIPECYEepsgvNYNL--YA 340
gi 551512852 261 KAPCSVNIQRARILHNGKKIWMENFEPNRVLHLDIVSVYCMNQAMKCGYAVPTQCIDGTLNIPECFEepsalEYTL--KP 338
gi 25136571  270 RARCPVPAQRSRVIVGGVKRWPYDLTDGVVAHGENVTFFCKHPEKLCSFTATEVCVDGELKAPSCYLdptwlQFKL--YP 347
gi 597786229 201 RARCPIPAQRSRVLVGGEKRWPYDLTDGMVAHGEEVTFFCKHPEKHCSYTAAATCFDSRLTAPSCYLdptwfQYKL--YP 278
gi 658893835 261 RARCVIPAERSRVVIGGVKRWPFDVTDAMVPHGENVTFYCKHPKKQCSFTAAQACFDGKLQTPECYLeptwlQYKL--FP 338
gi 410929735 263 RAPCTVGIKRGRIFYNSQKLWIADLKPNRVLHGEHVAFYCLNKADRCGYPVASTCRDGNLPIPECFEepgkiEYNI--RA 340
gi 551512850 261 RAPCEVGIKRGRIFYNARKIWIEDLRPNRVLHGEHVAFYCKDKAEKCGYPVASTCNDGNLPIPDCYEqpgkiEYNL--RS 338
                         90
                 ....*....|
1G4F_A        77 KTDASDVKPC 86
gi 597777038 341 GTLPSEIRMC 350
gi 637341966 341 KRVVSEIPAC 350
gi 348541779 341 GSLPSEIQQC 350
gi 551512852 339 NSLPSEIDQC 348
gi 25136571  348 HRLVSEIDAC 357
gi 597786229 279 HRLVSEINTC 288
gi 658893835 339 HRLVSEIETC 348
gi 410929735 341 KTLPSEIEMC 350
gi 551512850 339 KNLPSEIRAC 348
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