5KNW,1OWX


Conserved Protein Domain Family
RRM_3

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pfam08777: RRM_3 
Click on image for an interactive view with Cn3D
RNA binding motif
This domain is found in protein La which functions as an RNA chaperone during RNA polymerase III transcription, and can also stimulate translation initiation. It contains a five stranded beta sheet which forms an atypical RNA recognition motif.
Statistics
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PSSM-Id: 337198
View PSSM: pfam08777
Aligned: 14 rows
Threshold Bit Score: 92.4125
Threshold Setting Gi: 74855304
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5KNW_A     18 GvivkII--STEPLPgRKQVRDTLAAIS---EVLYVDLLEGDTECHARFKTPED-AQAVINAYTE-------INKKHCWK 84   human
Q6K6X2    330 G----LSgkANSPIS-REDLKEAFKKFG---TVRYVDFSIGDESGYLRFEDSKA-AEKARMSAVLade-gglIVKDHIVT 399  Japanese rice
Q54TG6    229 GvilcFKg-VGKGLH-RGDIKEIFSQYG---EVQFVGYNSDEENGSVRYKTAES-CKRAIESLTEtk----kEIGGQIPT 298  Dictyostelium dis...
Q7PWI4    261 GacvfMEg-LGKETT-RESIKEAIRALDetlEFAYIDYQKGDASGYVRFNKQDA-GKQLLEKLTDkk----lKIDDAEVT 333  Anopheles gambiae...
Q17EQ5    250 GacvhLAg-FNKETS-RETIKETILKLDeslEVAFIDYQKTDSEGTVRFAADDA-GKKFMEKLTDsk----iQIDEEEIT 322  yellow fever mosq...
Q7ZWE3    429 GvivkIS--YNQPLPsKRCIKDMLSELS---PVAYVDLLDGDTEGHVRFKSSED-AQKVIKARFEf-------QKKYNWN 495  zebrafish
Q4G0J3    454 GvivkII--STEPLPgRKQVRDTLAAIS---EVLYVDLLEGDTECHARFKTPED-AQAVINAYTEi-------NKKHCWK 520  human
O01806    230 GlilaVDg-LGPDST-IDSIKTFFKLHG---SVGYVAHENGGKTAEIRFNNDSEgAQKAWDNAVAagtdgkvILQEAELS 304  Caenorhabditis el...
1OWX_A     18 GcllkFSgdLDDQTC-REDLHILFSNHG---EIKWIDFVRGAKEGIILFK--EK-AKEALGKAKDann-gnlQLRNKEVT 89   human
CAF96679 1532 GvivkIT--DSKALPaRSRIKDALSRLS---PVAYVDVLEGDAEGHVRFHSPED-ARAACEGRAAl-------QKELGWR 1598 spotted green puf...
5KNW_A     85 LEILSGDHEQRYWQKILVDRQAKL--NQPREKKR 116  human
Q6K6X2    400 LEPVTGEAEKDYWNTIRGIQGKYK--DNRSYKGR 431  Japanese rice
Q54TG6    299 YNLLEGEEEKKEWEKIIERKKNAA--KNGGFKKG 330  Dictyostelium discoideum AX4
Q7PWI4    334 ADLLVDEKETEYLKKIAEEQAKRK--VNAKNKGR 365  Anopheles gambiae str. PEST
Q17EQ5    323 ARLLEGDEEKEFLRKVVKDQQARRqaSNARNKGR 356  yellow fever mosquito
Q7ZWE3    496 LELLSGDHERRYWQKILVDRQAKL--NTPREKKR 527  zebrafish
Q4G0J3    521 LEILSGDHEQRYWQKILVDRQAKL--NQPREKKR 552  human
O01806    305 ARVLDGEEEEKYWTEFNARKNQRQggGRGGRGGR 338  Caenorhabditis elegans
1OWX_A     90 WEVLEGEVEKEALKKIIEDQQESL--NKWKSKGR 121  human
CAF96679 1599 LEVISGEREQRYWQKILVDRQVKL--NRPREKKR 1630 spotted green pufferfish
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