5KNW,1OWX


Conserved Protein Domain Family
RRM_3

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pfam08777: RRM_3 
Click on image for an interactive view with Cn3D
RNA binding motif
This domain is found in protein La which functions as an RNA chaperone during RNA polymerase III transcription, and can also stimulate translation initiation. It contains a five stranded beta sheet which forms an atypical RNA recognition motif.
Statistics
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PSSM-Id: 337198
View PSSM: pfam08777
Aligned: 14 rows
Threshold Bit Score: 92.4125
Threshold Setting Gi: 74855304
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5KNW_A         18 GvivkII--STEPLPgRKQVRDTLAAIS---EVLYVDLLEGDTECHARFKTPED-AQAVINAYTE-------INKKHCWK 84
gi 75324043   330 G----LSgkANSPIS-REDLKEAFKKFG---TVRYVDFSIGDESGYLRFEDSKA-AEKARMSAVLade-gglIVKDHIVT 399
gi 74855304   229 GvilcFKg-VGKGLH-RGDIKEIFSQYG---EVQFVGYNSDEENGSVRYKTAES-CKRAIESLTEtk----kEIGGQIPT 298
gi 74800882   261 GacvfMEg-LGKETT-RESIKEAIRALDetlEFAYIDYQKGDASGYVRFNKQDA-GKQLLEKLTDkk----lKIDDAEVT 333
gi 122068844  250 GacvhLAg-FNKETS-RETIKETILKLDeslEVAFIDYQKTDSEGTVRFAADDA-GKKFMEKLTDsk----iQIDEEEIT 322
gi 82241469   429 GvivkIS--YNQPLPsKRCIKDMLSELS---PVAYVDLLDGDTEGHVRFKSSED-AQKVIKARFEf-------QKKYNWN 495
gi 121945944  454 GvivkII--STEPLPgRKQVRDTLAAIS---EVLYVDLLEGDTECHARFKTPED-AQAVINAYTEi-------NKKHCWK 520
gi 74956147   230 GlilaVDg-LGPDST-IDSIKTFFKLHG---SVGYVAHENGGKTAEIRFNNDSEgAQKAWDNAVAagtdgkvILQEAELS 304
1OWX_A         18 GcllkFSgdLDDQTC-REDLHILFSNHG---EIKWIDFVRGAKEGIILFK--EK-AKEALGKAKDann-gnlQLRNKEVT 89
gi 47213526  1532 GvivkIT--DSKALPaRSRIKDALSRLS---PVAYVDVLEGDAEGHVRFHSPED-ARAACEGRAAl-------QKELGWR 1598
                          90       100       110
                  ....*....|....*....|....*....|....
5KNW_A         85 LEILSGDHEQRYWQKILVDRQAKL--NQPREKKR 116
gi 75324043   400 LEPVTGEAEKDYWNTIRGIQGKYK--DNRSYKGR 431
gi 74855304   299 YNLLEGEEEKKEWEKIIERKKNAA--KNGGFKKG 330
gi 74800882   334 ADLLVDEKETEYLKKIAEEQAKRK--VNAKNKGR 365
gi 122068844  323 ARLLEGDEEKEFLRKVVKDQQARRqaSNARNKGR 356
gi 82241469   496 LELLSGDHERRYWQKILVDRQAKL--NTPREKKR 527
gi 121945944  521 LEILSGDHEQRYWQKILVDRQAKL--NQPREKKR 552
gi 74956147   305 ARVLDGEEEEKYWTEFNARKNQRQggGRGGRGGR 338
1OWX_A         90 WEVLEGEVEKEALKKIIEDQQESL--NKWKSKGR 121
gi 47213526  1599 LEVISGEREQRYWQKILVDRQVKL--NRPREKKR 1630
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