1M1J


Conserved Protein Domain Family
Fib_alpha

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pfam08702: Fib_alpha 
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Fibrinogen alpha/beta chain family
Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).
Statistics
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PSSM-Id: 312286
View PSSM: pfam08702
Aligned: 71 rows
Threshold Bit Score: 149.994
Threshold Setting Gi: 768942638
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1M1J_E        67 AGGCKHPLDELGVLCPTGCELQTTLLKQEKTVKPVLRDLKDRVAKFSDTSTTMYQYVNMIDNKLVKTQKQRKdNDIILSE 146 chicken
XP_016083774  61 qDWPFCTDDDWTYKCPSGCRLKGLIDETSQDFTNRITKLRNLLFEHQRSNKDSSSVTREMLELIRGDLVSGNeNDNLFGQ 140 platypus
XP_002716943  50 ADWPFCADDDWNQKCPSGCRMKGLIDEMNQDFTDRMNKLRNSLFDYQKNNKDSSSVVTNIMEYLRGNLATANnYDTTYNQ 129 rabbit
XP_003499519  49 TDWPFCSDEDWNHKCPSGCRMQGLIDEVNRDFINRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANnFDNTYGQ 128 Chinese hamster
XP_012660869  51 SDWPFCSDDDWNNKCPSGCRMKGLVDEVNQDFTNRINKLRNALFDYQKNNKDSNSLTRNIMEVLRGDFAKANnYDNAYNQ 130 small-eared galago
XP_011358657  50 TDWPFCSDEDWSQKCPSGCRMQGLIDEVNLDFTNRINKLKNALLNYQKNNKDSSSVTRNIMEILRGDFASGNhNDNTYNQ 129 large flying fox
XP_014964813  53 TGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTGRINKLRDSLFNYQKTNKDSNTLTKNIVEILRGDFAKANnNDNTFNQ 132 mouflon
XP_003476871  50 TGWPFCSDDDWNLRCPSGCRMQGLIDEVNQDFTNRIKKLKDSLFNYQKNNKDSSTY-RNIMEILRGKLSKDNnHDNTYNQ 128 domestic guinea...
XP_007496272  49 TDWPFCSDDDWTYKCPSGCRIKGLMDETNEDFTNRVTKIRNLLFDHQRNNKDSSSVTRNIMELLRGNMANDNtNNNALNQ 128 gray short-tail...
XP_003773168  50 ANWPFCSDEDWTYKCPSGCRIQGLIDETNEDFTNRITKIRNSLFDYQKNNKDSSSVSRNIMEILRGNTANDFnNGNSFGQ 129 Tasmanian devil
1M1J_E       147 YNTEMElHYNYIKDNLDNNIpSSLRVLRAVIDSLHKKIQKLENAIATQTDYCRSPCVASCNIP 209 chicken
XP_016083774 141 VSEDLRrRIETLKRKVSDQA-QRIINLQSSVRDQLVEMKRLEVDIDIKVRSCKGSCNRAYQYe 202 platypus
XP_002716943 130 VSEELRrRIEVLQRKVIEKV-QHIKLLQNNVRAQLIDMKRLEVDIDIKIRSCQGSCNRVLshe 191 rabbit
XP_003499519 129 VSEELRrRIEVLKRKVVEKA-QQIQVLQNNVRTQLIDMKRLEVDIDIKIRSCKGSCSRGVARE 190 Chinese hamster
XP_012660869 131 VSEDLRsRIEVLKRKVIEKV-QHIKLLQNNVRSQLVEMKRLEVDIDIKIRSCKGSCSRALVHQ 192 small-eared galago
XP_011358657 130 VSEDLRsRIEVLRRKVTEQV-QHIQLLQNNVRAQLVDMKRLEVDIDIKIRSCQGSCSRAVVRQ 191 large flying fox
XP_014964813 133 VSEDLRsRIEILRRKVIEQA-QHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALehk 194 mouflon
XP_003476871 129 VSEDVRsRIETLRRKVIEKA-QQIQLLQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRALsre 190 domestic guinea pig
XP_007496272 129 VTEDLRrRIEVLKRKVTEQV-QNIVSLQTNIRNQLVEMKRLEVDIDIKIRSCKGSCSRSLdre 190 gray short-tailed opossum
XP_003773168 130 VSDDLRrRIETLKVKVIEQV-QKIVSLQNSIRNQLVQMKQLEVDIDIKIRSCKGSCSRSLare 191 Tasmanian devil
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