3H32,1EI3,1M1J


Conserved Protein Domain Family
Fib_alpha

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pfam08702: Fib_alpha 
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Fibrinogen alpha/beta chain family
Fibrinogen is a protein involved in platelet aggregation and is essential for the coagulation of blood. This domain forms part of the central coiled coiled region of the protein which is formed from two sets of three non-identical chains (alpha, beta and gamma).
Statistics
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PSSM-Id: 370076
View PSSM: pfam08702
Aligned: 78 rows
Threshold Bit Score: 149.598
Threshold Setting Gi: 768942638
Created: 4-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3H32_B        62 AGGCLHADPDLGVLCPTGCQLQEALLQQERPIRNSVDELNNNVEAVSQTSSSSFQYMYLLKDLWQKRQKQVKdNENVVNE 141 human
XP_016083774  61 qDWPFCTDDDWTYKCPSGCRLKGLIDETSQDFTNRITKLRNLLFEHQRSNKDSSSVTREMLELIRGDLVSGNeNDNLFGQ 140 platypus
XP_002716943  50 ADWPFCADDDWNQKCPSGCRMKGLIDEMNQDFTDRMNKLRNSLFDYQKNNKDSSSVVTNIMEYLRGNLATANnYDTTYNQ 129 rabbit
RLQ77142      31 TDWPFCSDEDWNHKCPSGCRMQGLIDEVNRDFINRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANnFDNTYGQ 110 Chinese hamster
XP_023369206  51 SDWPFCSDDDWNNKCPSGCRMKGLVDEVNQDFTNRINKLRNALFDYQKNNKDSNSLTRNIMEVLRGDFAKANnYDNAYNQ 130 small-eared galago
XP_011358657  50 TDWPFCSDEDWSQKCPSGCRMQGLIDEVNLDFTNRINKLKNALLNYQKNNKDSSSVTRNIMEILRGDFASGNhNDNTYNQ 129 large flying fox
XP_014964813  53 TGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTGRINKLRDSLFNYQKTNKDSNTLTKNIVEILRGDFAKANnNDNTFNQ 132 mouflon
XP_003476871  50 TGWPFCSDDDWNLRCPSGCRMQGLIDEVNQDFTNRIKKLKDSLFNYQKNNKDSSTY-RNIMEILRGKLSKDNnHDNTYNQ 128 domestic guinea...
XP_007496272  49 TDWPFCSDDDWTYKCPSGCRIKGLMDETNEDFTNRVTKIRNLLFDHQRNNKDSSSVTRNIMELLRGNMANDNtNNNALNQ 128 gray short-tail...
XP_023361678  49 ANWPFCSDEDWTYKCPSGCRIQGLIDETNEDFTNRITKIRNSLFDYQKNNKDSSSVSRNIMEILRGNTANDFnNGNSFGQ 128 Tasmanian devil
3H32_B       142 YSSELEkHQLYIDETVNSNIpTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIP 204 human
XP_016083774 141 VSEDLRrRIETLKRKVSDQA-QRIINLQSSVRDQLVEMKRLEVDIDIKVRSCKGSCNRAYQYe 202 platypus
XP_002716943 130 VSEELRrRIEVLQRKVIEKV-QHIKLLQNNVRAQLIDMKRLEVDIDIKIRSCQGSCNRVLshe 191 rabbit
RLQ77142     111 VSEELRrRIEVLKRKVVEKA-QQIQVLQNNVRTQLIDMKRLEVDIDIKIRSCKGSCSRGVARE 172 Chinese hamster
XP_023369206 131 VSEDLRsRIEVLKRKVIEKV-QHIKLLQNNVRSQLVEMKRLEVDIDIKIRSCKGSCSRALVHQ 192 small-eared galago
XP_011358657 130 VSEDLRsRIEVLRRKVTEQV-QHIQLLQNNVRAQLVDMKRLEVDIDIKIRSCQGSCSRAVVRQ 191 large flying fox
XP_014964813 133 VSEDLRsRIEILRRKVIEQA-QHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALehk 194 mouflon
XP_003476871 129 VSEDVRsRIETLRRKVIEKA-QQIQLLQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRALsre 190 domestic guinea pig
XP_007496272 129 VTEDLRrRIEVLKRKVTEQV-QNIVSLQTNIRNQLVEMKRLEVDIDIKIRSCKGSCSRSLdre 190 gray short-tailed opossum
XP_023361678 129 VSDDLRrRIETLKVKVIEQV-QKIVSLQNSIRNQLVQMKQLEVDIDIKIRSCKGSCSRSLare 190 Tasmanian devil
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