3WJ9,5K1H


Conserved Protein Domain Family
eIF2A

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pfam08662: eIF2A 
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Eukaryotic translation initiation factor eIF2A
This is a family of eukaryotic translation initiation factors.
Statistics
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PSSM-Id: 285825
View PSSM: pfam08662
Aligned: 21 rows
Threshold Bit Score: 242.943
Threshold Setting Gi: 74971582
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3WJ9_A    210 KTFFKADKVQFKWNALGTSLLVLTQt---EVDKSNKNYYGETNLYLLGITGQFDCRVDLDREGPIHDVCWNADSKEFGIV 286  Schizosaccharomyc...
Q7QCA3    192 KSFFQADKVDMMWNRKGTGLILMTSt---DVDTTGVSYYGKQALHYM-TPKGDSCGIQLKAEGPIHDVAWSPKSTEFCVV 267  Anopheles gambiae...
Q9VNX8    232 KSFFQADRVEMLWNKRGSGLLLLTSt---EVDKSGASYYGNQAVHFM-ATKGDTCSVPLSKEGPVHCVKWSPKATEFVVV 307  fruit fly
Q54QW1    363 KSIWGATDARFHWQNEGAYLCVKTDkvatGKTKKEKIPTTSFELFRTHEPNVPIESFEIQYA--IKAFSWEPRGKRICII 440  Dictyostelium dis...
P55884    507 RNLFNVVDCKLHWQKNGDYLCVKVD----RTPKGTQGVVTNFEIFRMREKQVPVDVVEMKET--IIAFAWEPNGSKFAVL 580  human
Q8IJL2    358 KSFDNLDTLTCLWSISGQYLIFLVNt---N-DTTNKSYGYLSNCYFCSLVSKNIHIKRINEQV-AQDVKWSNIRDEFLII 432  Plasmodium falcip...
Q4XDF0     10 RNFQHLDNLVCLYSITGKYIIFLVSt---N-DTTNTSYGYVSNCYYCSLVSKSVNIKKINTQV-AQDAKWSTISDEFLII 84   Plasmodium chabaudi
Q4Z3V1    341 KKFFNSDEIKLKWNKNGTSLLLQIHt---QVDKEKQSYYGSSNLYFIDTVKIKDVNI-MTNKGLIYDTIWSYNQNKFYVC 416  Plasmodium berghei
Q4N7W3    280 KEFDASEEGELFWNSKGTSVLFRTFa---NSVKGLSSYYGANSLYLINLNNSKFKTISTVNDGIIHDISWSQNGKDFLLL 356  Theileria parva
OAP14346  214 RSFFRCSSVQFSWNHGSTGLLVVVQs---DVDKTNQSYYGETKLHYLTIDGTHEGLVPLRKEGPVHDVQWSFSGSEFAVV 290  thale cress
3WJ9_A    287 YG--YXPA-KTAIFDN-R----ANVVSIIPPAPRNTLIFSPNSRYILLAGFGNLQGSIDI-FDAAn-NXKKITTVEAANC 356  Schizosaccharomyc...
Q7QCA3    268 YG--FMPA-RATLFNL-K----CDAVYDFEPDNRNSVFFNDFGNLVVFGGFGNLPGYIET-WDLV--RRKKLANFKAPDT 336  Anopheles gambiae...
Q9VNX8    308 YG--FMPS-KAALYNL-K----CDVVFDFGEGPRNCAYFNPFGNLIALAGFGNLPGAVEV-WDVS--KREKLANLKCADT 376  fruit fly
Q54QW1    441 HGefKMNM-FVSFFEV-Qkt-sVKLISKLENRKLNTIFWSPRGTLVLLANLGDT-GELEF-YNTQ--DCESYGTQEHLQC 513  Dictyostelium dis...
P55884    581 HG--EAPRiSVSFYHV-KnngkIELIKMFDKQQANTIFWSPQGQFVVLAGLRSMNGALAF-VDTS--DCTVMNIAEHYMA 654  human
Q8IJL2    433 EG--KSDN-IILLYDH-D----LNVKCKIYSQYKNTIKWGPFGNMIALGGFGNLAGDINFyYKEVdnSVSIIKKYREACT 504  Plasmodium falcip...
Q4XDF0     85 EG--KSDN-IIYLYDS-N----LNVKSKISAQYKNTIKWCSFGNMIALGGFGNLAGDIDFyYKEKnyNTTLIKQYREPCT 156  Plasmodium chabaudi
Q4Z3V1    417 KG--EIPA-DIVLHDK-N----GNIIHSYGKHKFNTLKLNYSEKLLLTGGFGNLSGDISI-WNTI--NKKEITKTKSSCA 485  Plasmodium berghei
Q4N7W3    357 KG--PMPA-EIDLYDGvT----GLKTLSFGKNNRNTVKRDPFDRLVLMGGFGNLRGEIDI-WDMK--TKKKISQSKSECS 426  Theileria parva
OAP14346  291 YG--FMPA-CVTIFDK-N----CKPLMELGEGPYNTLRWNPKGRVLCVAGFGNLPGDMAF-WDVV--NKKQLGSNKAEWS 359  thale cress
3WJ9_A    357 TYCEFSPDSQFLLTAVTSpRLRVDNSIKIWHITGAPXFYEEF---NELYQA 404  Schizosaccharomyces pombe 972h-
Q7QCA3    337 TLLEWNPAGDTFLTATTApRLRMSNGFKVWHYSGALLGEYSWa--GELLEV 385  Anopheles gambiae str. PEST
Q9VNX8    377 TVFEWHPNGEWFVTATTApRLRISNGFKVYHYSGALLHETMWpqgQELLGI 427  fruit fly
Q54QW1    514 TGVDWNPSGRYVTTFVSHwKVQTDTGFNIWSFNGDLVYSVLK---DRFFQF 561  Dictyostelium discoideum
P55884    655 SDVEWDPTGRYVVTSVSWwSHKVDNAYWLWTFQGRLLQKNNK---DRFCQL 702  human
Q8IJL2    505 VLCDWSYDGTLFMTASTYpRMKVENVFKIYTYEGTLVNSYNF---NELYDV 552  Plasmodium falciparum 3D7
Q4XDF0    157 VLCDWSTDGTLFMTASTFpRMKVENTFKIYTYEGDLVNNYSF---NELYDV 204  Plasmodium chabaudi
Q4Z3V1    486 VICEFFNDDKHFLTATTHpRLRVDNNIKIFKYNGLIVSKLDF---DELYNV 533  Plasmodium berghei
Q4N7W3    427 VSCEFSPDGMYFVTATTVpRMRVDCCFKIFSYSGKLVQRVDF---EELYHV 474  Theileria parva
OAP14346  360 VTSEWSPDGRYFLTASTApRRQIDNGMKIFNYDGKRYYKKMF---ERLYQA 407  thale cress
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