Conserved Protein Domain Family
SPT16

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pfam08644: SPT16 
FACT complex subunit (SPT16/CDC68)
Proteins in this family are subunits the FACT complex. The FACT complex plays a role in transcription initiation and promotes binding of TATA-binding protein (TBP) to a TATA box in chromatin.
Statistics
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PSSM-Id: 337143
View PSSM: pfam08644
Aligned: 89 rows
Threshold Bit Score: 113.386
Threshold Setting Gi: 906373026
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q61E63        528 IFVDRKYDSVIVPIFGIPVPFHISMIKNCSQSVEGDFTYLRINFATPGSQ--VG-KDN-AQfp--hPLAHFMKELTFRAS 601  Caenorhabditi...
Q6C931        537 VHVDTRSQSIILPINGRPVPFHINTYKSGSKTDEGDYVYIRLNLSSPGQI--AG-SKKdAPqvfedPDAQFLRSITFRSR 613  Yarrowia lipo...
Q6BXE5        558 IHVDYKNQTIILPICGRPVPFHINSFKNGSQNEEGDFTYLRLNFNSPGAGgnVS-RRAeLPye-dsPENSFLRSVTLRSR 635  Debaryomyces ...
Q756A7        550 IHVDWKNQTFILPIYGRPVPFHINSYKNGSKNEEGEYTYIRLNFHSPGTGgvSK-KTEeLPye-dsPDHQFVRSLTLRSK 627  Eremothecium ...
XP_002836351  538 IVVDAKSQTIIVPVFGRPVPFHIATLKNASKTDEGDWTYLRINFLSPGQG--VG-RKDdLPfe--dPNAHFVRSLTYRST 612  Tuber melanos...
XP_011111880  550 IVVDVKAQTIILPIFGRPVPFHISTIKNVSKNEEDPFTHLRINLVSPGQG--VG-KKDeLPle--ePSAHFVRSLSYRST 624  Dactylellina ...
XP_018212903  545 IHIDSKNQTIILPICGRPVPFHINAFKNGLKTEEGEYTHLKLNFNSPGVA--VT-KKEeLPye-pgEDKQFIRSLTFRSK 620  Ogataea polym...
XP_011277524  536 IHVDHRTNTIIIPISGRPVPFHINAFKNGSKTEEGDYTYLRLNFNSPGAGgnTT-KKDeIPye-ddPKKEFLRSLTLKSK 613  Wickerhamomyc...
XP_002490662  547 ISIDPKAQTIILPICGRPVPFHINSFKNGSKNEEGDYMYIRLNFNSPGMG--SSvKKTeLPye-dgDDKEFVRSLTFRST 623  Komagataella ...
XP_013059070  497 IKVDRRAFSVIIPVFGAAVPFHIDVIKTATKTIEDGIGYLKISFYQP---------DRdVP-----TSANNLLSLVIKDT 562  Nematocida pa...
Q61E63        602 NIKEhhsdatppssnLSTAFRQIKEMQKRFRTEEAEEREKDGAVKQDKLILSQNKLNPKLKDLLIRPNI---IQKRITGS 678  Caenorhabditi...
Q6C931        614 HVEH-----------MNDVFKQIQDLKKASTKKEAEKKEMEDVVAQDSLVEVRARRPLKLDAVFVRPAP---DGKRVAGT 679  Yarrowia lipo...
Q6BXE5        636 DHQR-----------MVDVYKAIQDLKKDAVKREQEKKQMADVVSQANLVELKGSRVKKLDQVFIRPQP---DTKKIGGV 701  Debaryomyces ...
Q756A7        628 DGDR-----------MADIFKQITELKKESTKREQERKVLADVVEQAKLVENRTGRTKRLDQIFVRPSP---DTKRVPGT 693  Eremothecium ...
XP_002836351  613 DNDR-----------MAEICAAIQDMKKNAVKREQERKEMEDVVTQDNLVEIRNRRPQRLGDIYVRPAL---EGKRVPGE 678  Tuber melanos...
XP_011111880  625 DRNR-----------MAEISQAIQDMKKQALKRDQEKKEMEDVVTQDNLIEIKNRRPQRLPDVYVRPAL---DGKRVAGD 690  Dactylellina ...
XP_018212903  621 DNER-----------MSEVLKKITEMKKDAVKRESEKREQADVVTQASLIEVN--RPKRLDNVFVRPTP---DTKRLPGN 684  Ogataea polym...
XP_011277524  614 DGEH-----------MSKVYKEITDLKKESVKRETEKKAMADVVAQAKLIEAKPGRLRRLDNVFARPSP---DTKRVGGS 679  Wickerhamomyc...
XP_002490662  624 NKER-----------MSEVFKAITELKKTAVKRDQERKTMEDVVAQAQLVEFKG-RPKKLENVFVRPAP---DSKRVTGT 688  Komagataella ...
XP_013059070  563 QENV-----------M-TAWKEINNLKKEEEETEEEIEEGEQE----DLQEIAGRVE-TLQNVFMRCDHrmgTKKNVANT 625  Nematocida pa...
Q61E63        679 LEAHTNGFRY 688  Caenorhabditis briggsae
Q6C931        680 LEIHQNGLRY 689  Yarrowia lipolytica CLIB122
Q6BXE5        702 LQIHENGLRY 711  Debaryomyces hansenii CBS767
Q756A7        694 VFIHENGIRY 703  Eremothecium gossypii ATCC 10895
XP_002836351  679 VEIHQNGLRY 688  Tuber melanosporum Mel28
XP_011111880  691 IEIHQNGLRY 700  Dactylellina haptotyla CBS 200.50
XP_018212903  685 ITIHQNGIRY 694  Ogataea polymorpha
XP_011277524  680 LSIHENGLRY 689  Wickerhamomyces ciferrii
XP_002490662  689 LFIHQNGIRY 698  Komagataella pastoris GS115
XP_013059070  626 VELHKNGLRY 635  Nematocida parisii ERTm1
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