5IC9


Conserved Protein Domain Family
Utp13

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pfam08625: Utp13 
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Utp13 specific WD40 associated domain
Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome. Pwp2 is capable of interacting directly with the 35 S pre-rRNA 5' end.
Statistics
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PSSM-Id: 337133
View PSSM: pfam08625
Aligned: 158 rows
Threshold Bit Score: 87.9256
Threshold Setting Gi: 209878107
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5IC9_B           5 EQTLENYIHAGAYRDAIVLALQLNHPGRLLNLFTNVVTTRn----------------pD----------------PDSLT 52
gi 122052273   803 KSQINSLMLENNYRESLALSIKLNNIKLTNDILQKFRNKVi----------------fQ----------------GQKLE 850
gi 121976042   944 QDNFKQLIRNQDYINAVKLAFRFNFVSKFHQALELMFHKKdfkneiiyseneikqikkN----------------NEEED 1007
gi 330801473   699 kQHLDTALRKKDYYGALKLALVLDQPNQTLNIFKSMY---------------------Y----------------DDETV 741
gi 1160574529  798 QQSLDTSLRQRDFKRALKLALILNQPRQSLNIFNMMM---------------------------------------ESEN 838
gi 470253736  1095 QQMLDTSLLKKDYSRSLKLALILNQPHQSLRIFQTIVMEQ------------------Dkq------------ieENNQD 1144
gi 514691283   655 DQELNNLIQSQEYAEAFRRAVNKN------RPRTLLRLLR------------------H----------------LRDAD 694
gi 294896524   743 DTRIQMLLLQGNHKEALDLALKLRRPGLMKTVLEDHAWKS------------------L----------------TTAME 788
gi 471229436   207 qdnyQQHLRNQDYLNAARVAFQYNFVSKFHQSLELLFNRQ------------------NfqneiiytvsdmqfqiNENNI 268
gi 156085591   663 rTQVESLDADGKYSEALCLALELRKPHMASKILKRRCTTQlfr-------------veK----------------DHEIE 713
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5IC9_B          53 GL-K-----AVDDVLAKLSDEQ-----I---FQLLLRLRDWNTNARTAPVAQRVLWALFKSHPANKLSSLSvkga----- 113
gi 122052273   851 ND-------PIDYIIERIREGD-----EkllNNLLNFIKIWITNRKDYLLANLFINKLLKELKIEQLLKVE--------- 909
gi 121976042  1008 EFeK-----NIRELVTNLIELD-----I---NKLLIYIRDLNTMQKSSKVAQRLLNYVIRSIPIDDYQEISkkfkvpkkp 1074
gi 330801473   742 GV-S-----VVESCVSRLYDNE-----I---IKCLRYIRDWNTNSKFITISHVVLNAIIVNFKPDHLSRLSl-------- 799
gi 1160574529  839 GE-D-----LIKSTLKKFGKLD-----I---VKILKFVRDWNTNSKFVPVSQIILRSIMTMYLPSEIIKIH--------- 895
gi 470253736  1145 NN-S-----LMKSVLSKLSTND-----L---LKCLKYIRDWNTNSRFVHVSQIVLYSILTLLKAEQLLSFEk-------- 1202
gi 514691283   695 EM-D-----EVEPCIQQLDIEQ-----I---TRLLSFIENWNFNSKTSREAHELLNIIITTTSHDHLLKIP--------- 751
gi 294896524   789 GE-EapmdlDIGSWVEGLKEED-----L---EALVDVCGRWQTTARNCDLAHSVMNEIFKRLPASRLYRIE--------- 850
gi 471229436   269 ND-E-----EIQNLILNFMQLD-----F---NKLLYYIRDMNTIQKYSKVAQKVLNYVIMNTHIDQFEGLSknfkkqekq 334
gi 156085591   714 GD-------LFQSWVKGMKKSTdikrmL---TVAFDFIQLWISKGSTSWMANCLLSELLKQFKPCELFVVE--------- 774
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
5IC9_B         114 --------------rghkSLNEVLDAIKVYTERHYKRIEELVDESYLVEYTL 151
gi 122052273   910 ------------------GLLETIDFLLYNLSHHQNRLTNLQEKSYLMDMIT 943
gi 121976042  1075 skkeqeeqtkipsdseksEFEQLLQVIISYSKRHAERMERFIKKSYYLDFVL 1126
gi 330801473   800 -----------------nEFPKLLESLIPYTDRHFQRIDRMLQKTYLIDFTI 834
gi 1160574529  896 ------------------ELPELLESLIPYNERHFQRLDRILQKTYLLDFTI 929
gi 470253736  1203 ------------------ELATLLESMIPYNEKHFNRVDRIIQKTYLLDYTI 1236
gi 514691283   752 ------------------NCAKTLDSLIAYSERHMRRIQQLTQKTAFLDYTH 785
gi 294896524   851 ------------------GIASFLDSFVAYGAKHLRRLEAHTSRAFLCDGIL 884
gi 471229436   335 kken-nkddkinnctpqqEFINMLEILISYSQRHGERMEKFIKKSYYLDLVL 385
gi 156085591   775 ------------------GMSNRIESLLAYQASHLTRFINLSEKSHLLDVLL 808
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