6ND4,5IC9


Conserved Protein Domain Family
Utp13

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pfam08625: Utp13 
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Utp13 specific WD40 associated domain
Utp13 is a component of the five protein Pwp2 complex that forms part of a stable particle subunit independent of the U3 small nucleolar ribonucleoprotein that is essential for the initial assembly steps of the 90S pre-ribosome. Pwp2 is capable of interacting directly with the 35 S pre-rRNA 5' end.
Statistics
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PSSM-Id: 400791
View PSSM: pfam08625
Aligned: 149 rows
Threshold Bit Score: 89.0958
Threshold Setting Gi: 209556101
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6ND4_R        585 EQSLQNYMSKGDWTNAFLLAMTLDHPMRLFNVLKRALgesrsr---------qdteegKIEVIFNe---------eLDQA 646  Saccharomyces...
XP_011680799  119 KQQLSNLMHSKKFTKALRLAITLDQPFKALGIIRTIL----------------------EEPDGEa---------qLAIT 167  purple sea ur...
XP_002606134  637 EQELSNLIHEGRFLKAIGLAITLEQPYRVLTIVTDIL----------------------KKPEGKs---------qLEKT 685  Florida lancelet
EKC37300      738 EQQLSNLLHKKKYLRAIGLAITLEQPFRVLNIIKEIL----------------------YNPDGKt---------eLEKT 786  Pacific oyster
XP_011602176  667 QQELSNLLQEKKYLKALGLAISLDQPHTVLTVIKAIRq--------------------TEDSSEL-----------LEKT 715  torafugu
XP_006637433  661 QQELSNLLHEKKYLRALGLAISLNQPHTVLRVIKEI----------------------RGEEEGQe---------qLDRT 709  spotted gar
O18215        656 DQTLTNLLSQKRYSEALVFALTLAKPFCAFKVINALMa--------------------EETPEe------------LGSA 703  Caenorhabditi...
1_pfamImport    1 DQTLTNLLSQKRYKEALVFALTLAKPYCAFKVISALIsd------------------eSEEELGL--------------A 48  
EEA06146      788 ITQVDVLIKQNNLIEALNLALDLNLQLKTFQALEKILqpkfnnffssksldgsynlsnYQDKIELarieqieyiggLKEW 867  Cryptosporidi...
XP_001610205  663 RTQVESLDADGKYSEALCLALELRKPHMASKILKRRCttqlf------------rvekDHEIEGDl----------FQSW 720  Babesia bovis...
6ND4_R        647 ISILNDEQL-----ILLMKRCRDWNTNAKTHTIAQRTIRCILMHHNIAKLSEIPGMVKIVDAIIPYTQRHFTRVDNLVEQ 721  Saccharomyces...
XP_011680799  168 ITKLRPDQI-----ESVLRFAQTWNMNSKHCHVAQCVLGIIFRSQDPDDLAKFPGVKDILEGLMPYTDRHFQRLSRMLQQ 242  purple sea ur...
XP_002606134  686 LKKLREDQI-----DAVLKFVVQWNTNSRNCHQAQAVLSIILKNFPPDQLAQFPSIKTAIEGLVPYTERHFQRLNRLLQQ 760  Florida lancelet
EKC37300      787 LQKLRVDQI-----DSVLRFAGEWNTNSRHCHEAQFVLNTVFKTYPPEEILKFPNIKSTMEAFIPYTERHFQRMNRLLQQ 861  Pacific oyster
XP_011602176  716 VLKLRVDQK-----EALLRYCGVWNTNAKNCQDAQVVLQVLLTHVPPEELLQYQGARTHLEGLVPYTERHMQRIGRLLQA 790  torafugu
XP_006637433  710 VLKLRQDQK-----EALLGYCVVWNTNARNCQEAQAVIQALLRHLSPEQLLQCKGLRSALEGLLPYTERHFQRIGRLLQA 784  spotted gar
O18215        704 IRRLDTRQI-----EILLQFTVKWNTNSRTSSVAQRVLYEIVHIVDPEELVSMPGAYGYIESFLPYTQRHMDRLDRAKQD 778  Caenorhabditi...
1_pfamImport   49 ISRLDTRQT-----EILLQFCVKWNTNSRTSHVAQRVFFEIIHLVNPDDLIGMPNAFSYIESLLPYTQRHMDRLDRARQD 123 
EEA06146      868 FRQLSVNQI-----AIILKFTLEWVTIPKTVWLANTVMIFILCTINPSVLYKVEGFTQISAAFRAYNEKYKSRWLSLDQK 942  Cryptosporidi...
XP_001610205  721 VKGMKKSTDikrmlTVAFDFIQLWISKGSTSWMANCLLSELLKQFKPCELFVVEGMSNRIESLLAYQASHLTRFINLSEK 800  Babesia bovis...
6ND4_R        722 SYILDYALVEM 732  Saccharomyces cerevisiae BY4741
XP_011680799  243 AMFVQYTWQVM 253  purple sea urchin
XP_002606134  761 AMFVEYTWQQM 771  Florida lancelet
EKC37300      862 AMFLEFTWSCM 872  Pacific oyster
XP_011602176  791 SMFLNYMWQKM 801  torafugu
XP_006637433  785 SMFLDYMWQHM 795  spotted gar
O18215        779 VSLFDFVWRQM 789  Caenorhabditis elegans
1_pfamImport  124 VSLFDFVWKQM 134 
EEA06146      943 AYLLDYLFLPN 953  Cryptosporidium muris RN66
XP_001610205  801 SHLLDVLLGYN 811  Babesia bovis T2Bo
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