3A4L


Conserved Protein Domain Family
KTI12

?
pfam08433: KTI12 
Click on image for an interactive view with Cn3D
Chromatin associated protein KTI12
This is a family of chromatin associated proteins which interact with the Elongator complex, a component of the elongating form of RNA polymerase II. The Elongator complex has histone acetyltransferase activity.
Statistics
?
Aligned: 19 rows
Threshold Bit Score: 252.217
Threshold Setting Gi: 146345494
Created: 3-May-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3A4L_A         6 LIILTGLPGVGKSTFSKNLAKILSK---------NNIDVIVLG-SDLIR------ESFP--VW-KEKYEEFIKKSTYRLI 66  Methanocaldococ...
Q86H29         3 LIVLSGPPCSGKTTRAKELYEHFTN---------LGKKVIIIN-EESLLi-----NKNEg-YK-DSLTEKMTRGSLKGAT 65  Dictyostelium d...
O46079         3 LVVITGLPASGKSTRARQLRDHFVE---------RGRKVHLISeNEAVPka--gfGKNS--HTgDSQKEKVVRSDLKSEA 69  fruit fly
Q7Q9K5         3 LIVITGLPRSGKTSRAKELEKYFTEl--------GKGPVHIVS-EADCIarsgcgVKES--FT-DTGKEKQIRASLKSEA 70  Anopheles gambi...
Q5I0L7         3 LVVVCGLPSSGKSRRTEELRRALTG---------EGRSVYVVD-DASVLg-----AQDStvYG-DSAGEKALRAALRAAV 66  Norway rat
Q58933         2 LIILTGLPGVGKSTFSKNLAKILSK---------NNIDVIVLG-SDLIR------ESFP--VW-KEKYEEFIKKSTYRLI 62  Methanocaldococ...
Q6LX62         2 LIILTGLPSVGKSTFSKAFSKKMAE---------KNIDNIILG-TDLIR------ESFP--VW-KESYEEFIRDSNNYLI 62  Methanococcus m...
Q9LMH0         3 LVVICGQPCSGKSIAAVTLAETLKEs-------eTKQSVRIID-EASFHl-----DRNQn-YA-NMPAEKNLRGKLRSDV 67  thale cress
CAP38298       3 LIIVTGHPASGKSTIVDRLAQKFSE---------SQKECQIIR-DDAYGs----fSRKN--YE-FANKEKDLRSWIRSEV 65  Caenorhabditis ...
XP_024513725   3 LVTITGFPCSGKSTRAQQLKQYFEKrlkepeydgPALEVVVVD-DESSHv-----PRST--YD-SSAQEKPGRASLFSNV 73  Cryptococcus ne...
3A4L_A        67 DSAL-KNYWVIVDDTNYYNSMRRDLINIAKKYNKNYAIIYLKAS-----------------LDVLIRRN-----IERGEK 123 Methanocaldococ...
Q86H29        66 DRNLsKDTVVISDSLNYIKGYRYELYCIARAAGTRLLVLYCNTP-----------------RDLAKKWN-----QERDQS 123 Dictyostelium d...
O46079        70 SRHLnQEDLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIP-----------------QEEAWTFN-----SQRTAP 127 fruit fly
Q7Q9K5        71 MKLLtKSTLVIMDGTNYIKGYRYEIFCMSKNARTTQCTVHCAMT-----------------VEQRNARR-----EEIVQS 128 Anopheles gambi...
Q5I0L7        67 ERRLsRQDVVILDSMNYIKGFRYELYCLARAVRTPLCLVYCIRPgwpsrglpvpgacessdPAVSVSWRpradyGEKTQA 146 Norway rat
Q58933        63 DSALkN-YWVIVDDTNYYNSMRRDLINIAKKYNKNYAIIYLKAS-----------------LDVLIRRN-----IERGEK 119 Methanocaldococ...
Q6LX62        63 KEALeNKFSVIVDDTNYYNSKRRDLMNIAKECDTNYVTIYLKAP-----------------LNLLLKRN-----IERGQK 120 Methanococcus m...
Q9LMH0        68 DRSVsTGEIVIVDSLNSIKGYRYELWCIARAAGIRYCVVYCDVD-----------------EAHCRQWN-----KERSDR 125 thale cress
CAP38298      66 QQNLtKNKVVICDGLNYIKGYRYELFLAAKMSKTTYCVIQVTPS-----------------SDTCHWLN-----EQKPEG 123 Caenorhabditis ...
XP_024513725  74 NRSLgTDTITIVDSANYIKGFRYQMYCAAREAHTRVATIHVVAP-----------------PDMCRKWH-----EKRGEC 131 Cryptococcus ne...
3A4L_A       124 -----------------------------------------------------IPNEVIKKMYEKFDEPGKKYKWDEPFL 150 Methanocaldococ...
Q86H29       124 v---------------------------------------------------aYSEKLLDELTNRFEVPNPKNRWDSPLF 152 Dictyostelium d...
O46079       128 delpgdserv----------------------------------qpvdnsdvpYTRETFDALCQRYEEPQSNNRWDSPLV 173 fruit fly
Q7Q9K5       129 sss------------------------------------------------geLDAETFDALCQRYEEPQDTSRWDRPLF 160 Anopheles gambi...
Q5I0L7       147 vgaveqraisplanggvptavpkeldpkdilpsnppavmtpeseksaepapcaFPPELLESLALRFEAPDSRNRWDRPLF 226 Norway rat
Q58933       120 -----------------------------------------------------IPNEVIKKMYEKFDEPGKKYKWDEPFL 146 Methanocaldococ...
Q6LX62       121 -----------------------------------------------------IPNEVIKNMYEKFDTPGTKYAWDLPDI 147 Methanococcus m...
Q9LMH0       126 ge-------------------------------------------------dgYDDGIFEDLVRRFEKPERRNRWDSPLF 156 thale cress
CAP38298     124 e---------------------------------------------------rYSREIIDQLLMRYEKPDTKFRWEQPLF 152 Caenorhabditis ...
XP_024513725 132 s----------------------------------------------------YKQATFDNLIMRYEEPSSMVRWDSPLF 159 Cryptococcus ne...
3A4L_A       151 IID-----TTKDIDF----------------------NEIAKKL-----------IEKSKEIPKFYVLeENKN-KNNNIS 191 Methanocaldococ...
Q86H29       153 TLE-----PQHTLPH----------------------ELLFKTL-----------FEVQELRPNYATQ-SQSL-SPANFV 192 Dictyostelium d...
O46079       174 VVL-----PKDTLDM----------------------EAIYKAL-----------YESQPLPPNQSTY-NAPL-GTTNYL 213 fruit fly
Q7Q9K5       161 TVY-----GGEEMEL----------------------ARIHSAL-----------YEQAPLPPNLATQ-NMPL-SATNFL 200 Anopheles gambi...
Q5I0L7       227 TVVg----LEEPLPL----------------------AEIRSAL-----------FENRAPPPHQSTQ-SQPL-ASGSFL 267 Norway rat
Q58933       147 IID-----TTKDIDF----------------------NEIAKKL-----------IEKSKEIPKFYVL-EENKnKNNNIS 187 Methanocaldococ...
Q6LX62       148 TVD-----TTEKIDY----------------------NEILNEIle--------iNENKNLKIEEDKI-PKSE-PVESDL 190 Methanococcus m...
Q9LMH0       157 ELYpsrevIDKSSPV------------------------ILEAVtyltktvdsktQDVRILQPSIATQ-AARF-SEANSL 210 thale cress
CAP38298     153 EVKig--kAEKALPTeidddmsidleypaprfanifdDEIVEWI-----------CNGTQLTENQSTQ-TVPL-APTNFL 217 Caenorhabditis ...
XP_024513725 160 TVP-----WDEDPPF----------------------EDIWNAI-----------IKGDKKPPTSAVL-QRSK-PPPNTL 199 Cryptococcus ne...
3A4L_A       192 DKIDKETRKIVSEYIK----SKKLDKDK----------------------IKEVVELRKEF--LKKIKk-------MEEV 236 Methanocaldococ...
Q86H29       193 HELETKTQEITSVISDalqsSMVGDYIKvpgtekrv-------vihsklnLVELRNQRRQF--YKFAQ--------LHPP 255 Dictyostelium d...
O46079       214 FELDKIVQAIIKEILGav-kIKAFGQLRipgsrnpv-------kvatsmnALQLNRLRQKF--ITSTCha----sqTSPT 279 fruit fly
Q7Q9K5       201 FELDKSTQTIIDQIAAar-kIGLDGPVEipqagmra-------evpanmsVAQLNRHRRQF--LNYVKmh-----tNVSS 265 Anopheles gambi...
Q5I0L7       268 HQLDQATSQVLTAVMEaqksAVPGDLLTlpgttehl-------rftrpltLAELSRLRRQF--ISYTKm------hPNNE 332 Norway rat
Q58933       188 DKIDKETRKIVSEYIK----SKKLDKDK----------------------IKEVVELRKEF--LKKIKk-------MEEV 232 Methanocaldococ...
Q6LX62       191 VKIDSLTRNIVGNLIK----TGKIDKKD----------------------IKLLSEIRKSF--LKDCKki-----eSEKL 237 Methanococcus m...
Q9LMH0       211 YELDRATQEIINAIVEqqslGAAISRVTlgnelppi-------eicrpigLPELRRLRRTF--VKLMGqssl-sgpPLPT 280 thale cress
CAP38298     218 HELDRCTQDVVTVLLNaqrtAVRGQNLTipgasegsn----qvkflklrtLPELNRLRHQF--VNMSKk-------DPMS 284 Caenorhabditis ...
XP_024513725 200 QTLTATTSLINSSLLShltsLPNSTTFPipsppapsssslvlhlpakkitLSEMSRLKRQYetVQVKAqasgglaaAGNW 279 Cryptococcus ne...
3A4L_A       237 DADRVLKEFKDLLN 250 Methanocaldococcus jannaschii
Q86H29       256 QPHLIADSFVDFLN 269 Dictyostelium discoideum
O46079       280 PLEQVPHLFVQFIN 293 fruit fly
Q7Q9K5       266 DISKIPAIFVQFLN 279 Anopheles gambiae str. PEST
Q5I0L7       333 NLPQLANMFLQYLN 346 Norway rat
Q58933       233 DADRVLKEFKDLLN 246 Methanocaldococcus jannaschii DSM 2661
Q6LX62       238 DFEKIEKDFLDYLN 251 Methanococcus maripaludis S2
Q9LMH0       281 DADSAKRRFVDYLN 294 thale cress
CAP38298     285 DKEKIINGFVDFLN 298 Caenorhabditis briggsae
XP_024513725 280 TEGDVATGYVRFLE 293 Cryptococcus neoformans var. neoformans JEC21
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap