3GZH,3BHG,4MX2,2QGA,4EFC


Conserved Protein Domain Family
ASL_C

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pfam08328: ASL_C 
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Adenylosuccinate lyase C-terminal
This domain is found at the C-terminus of adenylosuccinate lyase(ASL; PurB in E. coli). It has been identified in bacteria, eukaryotes and archaea and is found together with the lyase domain pfam00206. ASL catalyzes the cleavage of succinylaminoimidazole carboxamide ribotide to aminoimidazole carboxamide ribotide and fumarate and the cleavage of adenylosuccinate to adenylate and fumarate.
Statistics
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PSSM-Id: 337004
View PSSM: pfam08328
Aligned: 241 rows
Threshold Bit Score: 105.962
Threshold Setting Gi: 609234967
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3GZH_A       357 SRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHN-WEVLAEPIQTVMR------RYGIEKPYE 429 Escherichia col...
Q4UB18       277 SRMQRDLSDSSVLRNLGVAFAHSVVAYNSILSSLERMYFDESTSKLEIQEN-WNILSEPVQLNLK------MMGHMDAFE 349 Theileria annulata
XP_002784089  34 SRMQRDLTDSTVQRAVGSAFAHTIIAIDSTIKGLSKVMVSAPIANRELEDH-WAVTGEAVQTVMR------RYGLERPYE 106 Perkinsus marin...
XP_003882717 261 SRMQRDLSDSTVLRNVGVAFGHCLVAYESTKKGLGRVDVNRAAMLRELENH-WAVLGEPMQTVLR------KRGVRNAYE 333 Neospora caninu...
ACV64561     328 SRMQRDLSDSSAQRNIGAAIAYSYIAINSTLRGFRKISINPKTIEDDFEEA-WEVIAEAVQTVMR------KHGYCNPYE 400 Desulfotomaculu...
SCH66293     333 SRMQRDLSDSSSQRNIGLAFGYSLQAISETTNGLAKCVVNKDKLAADLNEK-WEVLAEPIQTMLR------KYGISDAYD 405 uncultured Clos...
XP_001611211 336 SRMQRDLSDSTVLRNVGVAFCHSYLAYLSILKAFSRISVNESRALEELDAN-WVVLSEPLQIHLR------MTGDASGYE 408 Babesia bovis T2Bo
WP_024268138 324 SEHQRDLSNSASGRFTVEILAGFAAAVKRMVKILSGMTVNMKGLQRNLENAgSSVLAEPAYILLS------SQGEADAHE 397 Spirochaeta sp....
WP_013337225 322 SRLQRDLSDSTIKRNIGLGIGHVILGVRRLNTVLSSINVNEDAISRDLNEH-WEVLSEAVQVRLR------ALGMADAYE 394 Vulcanisaeta di...
Q83FF1       328 SRLQRDLSDSSVQRNIGVALGHSLVAIDNLKRGLAGIRLNKNRLTEDLNNN-WEVIAEAVQTTIRaeilacKSNEANPYE 406 Tropheryma whip...
3GZH_A       430 KLKELTRGKRVDAEGMKQFIDGL--A-LPEEEK--ARLKAMTPANYI 471 Escherichia coli O157:H7
Q4UB18       350 KVLVFTRGFNPSKDEMLKFIEEN----CGKD----SRLLTLKLEEYl 388 Theileria annulata
XP_002784089 107 RLKEFTRGREIDATSMKEFTENIgrE-IGEDKPgvKGLENLTPQTYI 152 Perkinsus marinus ATCC 50983
XP_003882717 334 KLKSATRGQAIDKERMQDIVEACgaDlLPEDV---DALRSLTPATYT 377 Neospora caninum Liverpool
ACV64561     401 RLKEITRGKMIGKEEIRAFISSV--E-LPEEDK--MRLMELSPQKYI 442 Desulfotomaculum acetoxidans DSM 771
SCH66293     406 QLKELTRGKNISQEAIMEFAKGL--DvLSDEDR--QTLLDMTPASYI 448 uncultured Clostridium sp.
XP_001611211 409 KMLSLTRTGCVSKETMKDIISDNcgN------N--TDLKSLTPSKYI 447 Babesia bovis T2Bo
WP_024268138 398 IIRKFTLKAEQEEKSLSEVMKSD--KaVWEKIS--RRLEAvgvdnpd 440 Spirochaeta sp. L21-RPul-D2
WP_013337225 395 RALAIFRGSRMGMEDYKKALGEL--G-VNDD-----ILRGLSPDKYV 433 Vulcanisaeta distributa
Q83FF1       407 RLKDFTRNKKITKHTLDEFITNL--D-LSEHAK--KRLLELTPSKYT 448 Tropheryma whipplei str. Twist
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