1NF2,4DWO,4ZEW,3L7Y


Conserved Protein Domain Family
Hydrolase_3

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pfam08282: Hydrolase_3 
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haloacid dehalogenase-like hydrolase
This family contains haloacid dehalogenase-like hydrolase enzymes.
Statistics
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PSSM-Id: 311955
View PSSM: pfam08282
Aligned: 66 rows
Threshold Bit Score: 155.081
Threshold Setting Gi: 74862782
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1NF2_C   5 FVFDLDGTL-LN-----DNLE-IS-EKDRRNIEKLS---------RKCYVVFASGRMLVSTLNVEKkYFK--RT---FPT 62  Thermotoga maritima
Q86KT5   6 IALDLDGTI-LN-----SNKQ-VS-ENSKRVLQYISkpefknidgEEVLVLLASGRAPYLVSPVEE-ALG--ID---CYL 71  Dictyostelium discoideum
Q97GE4   6 IFFDIDGTLlVH-----NGKEsTIpYSTKEALKKLKe--------KGHNLFICSGRPIRFAIQEFQ-EMV-------DGY 64  Clostridium acetobuty...
Q8XN14   8 VFFDVDGTL-IDcgkglYKPS----NKTKEAIKKLKe--------NGYLTILATGRPMSFVDDGLK-ELE--LD----GY 67  Clostridium perfringens
Q98Q20  11 IISDIDGTI-LP-----YGWKrVS-DKTVESFQKLKe--------NNYYTALATGREYVTIGDVLD-QVG--HS---DFF 69  Mycoplasma pulmonis
Q9CP34   3 FVFDLDGTI-CF-----DGKQ-IP-LNIQHALEQLMq--------KDHQLIFASARPIRDLLPLLNpKLQq------AML 60  Pasteurella multocida
Q8EW86 504 LVFDLDGTL-LN-----ENKR-VN-VETISAMQKAYq--------EGHELVIATGRSYQQTIDVVN-QVG--VV---RYA 561 Mycoplasma penetrans
Q8XM70   4 FVSDLDGTL-LN-----KDQV-IS-DYSKKELNRLIs--------TGVNFAIATARSPATVSDILD-GID--IK---TPV 61  Clostridium perfringens
Q7NAL6   8 VISDLDGTL-IRy---eNNKHiVE-PAAIHAIEKLAs--------RDITFTIATGRKQSDVVNLIK-TYN--LSgmvRYI 71  Mycoplasma gallisepticum
Q83FJ6   6 IALDIDGTV-LN-----HDGHtPS-EGIVAQLARLV---------REHYLVFASGRSTGDTLPVLE-SLGltQGampQFI 68  Tropheryma whipplei s...
1NF2_C  63 IAYNGAIVy---LPEEGVI-LNEKIP---PEVAKDIIEYIKPLN-VHWQAYI---DDVLYSEKD-------NEEIKSYAR 124 Thermotoga maritima
Q86KT5  72 IGYNGSICfgrkSEGRNTV-FSHSID---NSNLKAIFKYVEENN-LFLNIYG---DGIVYGIDKpe----lAEKPRRYSI 139 Dictyostelium discoideum
Q97GE4  65 ICCNGTYI----VYNGKCI-YNKLID---KDTLKYLIKEFCKLG-ISASFSG---AYNGYSYNM-------SSEKIHQMN 125 Clostridium acetobuty...
Q8XN14  68 IASNGTYI----ELNNEVI-LNDDIK---LEKLKEIMDYCVEHN-INFILEG---QKTSYVLNN---------DVAKKMV 126 Clostridium perfringens
Q98Q20  70 IGANGSFIy--dIKNKKEI-YSNYLN---FDNVKKFSKFFKANFnNDLMFVT---DDKWIHLSDin---hsHLDQSWFLA 137 Mycoplasma pulmonis
Q9CP34  61 IGGNGAIT----QVNKQIT-AQQPIS---SVAFTQIKQWIEEFD-LDYL------ADDLWDYSK--------------RL 111 Pasteurella multocida
Q8EW86 562 VMNNGALIy--dKENNKIFrNTDPLP---KDLIKYFFEIVFSKN-IPFLLYS---DLNVYMYNFtnd-dkkVFLPYINER 631 Mycoplasma penetrans
Q8XM70  62 VLMNGVIIf--dIEKKKYI-DVKEID---KESVKEIIKILQEYN-KTFFLYGi-kDDYLWVYHKdftydfeREYYEERCN 133 Clostridium perfringens
Q7NAL6  72 IACNGAVIy--dIEEEKII-QNSYLTkkvKTAVMKHVDAFKEMT-QDFLLFSydiNNNIYLYDPnkk-pneSLLKELTSY 146 Mycoplasma gallisepticum
Q83FJ6  69 ICCNGAVTl--kMENNEYV-RHRVISfdaSRTLEYIINTLPG---VELAVER---CDGVYMHTS-------------NFP 126 Tropheryma whipplei s...
1NF2_C 125 HSNVDYRVEPNLSELVSKMGTTKLL-----LIDTPERLDEL--KEILSERFKDVV------KVFKSFPTYLE--IVPKNV 189 Thermotoga maritima
Q86KT5 140 MTGATYKLIPSYSTLPEDFTPAKCLi----ILDDDKECDQL--LETMRPLFPTLSlvksncMNKDYKQYYVE--FLEHGV 211 Dictyostelium discoideum
Q97GE4 126 RFYKTENPYILDNWNIEEIEANNVDv----FFKNNEHMEKC--IKYLEHK-----------LIFNTHKPYLSadVSFKNW 188 Clostridium acetobuty...
Q8XN14 127 ENFSLPEESFTGDWTEEELSANKLVi----VDNNKDDFKDI--FERFKDEFV---------FMQHPGHSSYD--MYRRGC 189 Clostridium perfringens
Q98Q20 138 NHKDKFKDIADKSINKEKISILTI------VSKDENVYNEC--KGFIEKNCPEI-------EINTKWSSGFF--VSSKGT 200 Mycoplasma pulmonis
Q9CP34 112 RQPHSIEHKIDPAKLAQNRPLSAIQhpiktILLNLTQTQFLflKQQLTHLEVNLIe-----HSEENGRFNLD--ITAKHI 184 Pasteurella multocida
Q8EW86 632 TIDISGMSIDELFKYLNNNNIDLFNlcahcEALTEEDWVQM--FKYYKEDLKLC-------NLTSALKGSID--IYGASI 700 Mycoplasma penetrans
Q8XM70 134 KKLKSFKKVENYLDILDDNQIINFVffednKLIAHELFEKIlkVKGVTGNCYK--------DIYNEGAFFLD--VYNEEA 203 Clostridium perfringens
Q7NAL6 147 EGSFSSNNYIYIDDLNERDDLIKLI-----FFYNRSSMTED--ITDYLAKFIKLTkid-tnDCVVVSPMSFE--LNSADC 216 Mycoplasma gallisepticum
Q83FJ6 127 LDYLHDKRILSSVSEIVHTPPARVV-----VYEASIDASEI--AKRFESRC----------INFNNAWGYWD--IMPPGV 187 Tropheryma whipplei s...
1NF2_C 190 DKGKALRFLRERMNWKKEEIVVFGDNENDLFMFEEA----GLRVAMENAIEKVKEASDIVTLTNND-SGVSYVL 258 Thermotoga maritima
Q86KT5 212 NKGTSVIDFCKAKSIDSSKVVAFGDAENDNEMLEQS----GLGICLANGTDITKSIANKVSQYTNDqDGVAREL 281 Dictyostelium discoideum
Q97GE4 189 DKSKGIEYLVKYMKRDMKDTMAFGDGKNDITMLKTV----NIGIAMGNAVDEVKNKADMVTDSAAD-DGIYNAL 257 Clostridium acetobutylicum
Q8XN14 190 TKAHGIEHLIKELGLSDKDTYAFGDGENDIEMFQRV----KYGIAMGDAHETLIPHAYKQTENVPN-EGIYKAL 258 Clostridium perfringens
Q98Q20 201 NKLSAAKALSTHLNSSIDQVMAFGDSENDIEMIKGV----GHGIAVANALDSVKKVAKLVVGPANK-DGVFHYL 269 Mycoplasma pulmonis
Q9CP34 185 NKYYTLTTYI-----GQAKYVAFGNDMNDIELLQHA----DYSVCVGDFAPLRKLANTHLFANPAD---IAQKI 246 Pasteurella multocida
Q8EW86 701 SKYIGYLKLKEMINCFDDDVYFFGDSNNDYDLMSHL----ENGVAMGNANPRLKAISKYVIGDNNS-TAIADFI 769 Mycoplasma penetrans
Q8XM70 204 SKANGIKFLA--DYVEHSKVITFGDGENDVPMFEIA----DECYALENASAGLKAIATGIIGNNND-DAVVRFL 270 Clostridium perfringens
Q7NAL6 217 NKGNAVLELNKILKKDLAKTLSIGDSFNDIPMFKVT----GVSVTLESSHREVQNNATNVLDVKAS-DVVADAI 285 Mycoplasma gallisepticum
Q83FJ6 188 NKSTGLSFVQQSLCVSGDMVVSAGDGFNDIEMLEWTksigGRSFAMGQAPARVKQAALKVIGTVYD-GGLAKEL 260 Tropheryma whipplei str. Twist
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