Conserved Protein Domain Family
RNase_P_pop3

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pfam08228: RNase_P_pop3 
RNase P subunit Pop3
This family of fungal proteins form a subunit of RNase P, the ribonucleoprotein enzyme that cleaves the leader sequence of precursor tRNAs to generate mature tRNAs. The structure of Pop3 has been assigned the L7Ae/L30e fold. This RNA-binding fold is also present in human RNase P subunit Rpp38, raising the possibility that Pop3p and Rpp38 are functional homologs.
Statistics
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PSSM-Id: 254674
View PSSM: pfam08228
Aligned: 5 rows
Threshold Bit Score: 158.06
Threshold Setting Gi: 74582454
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74692658  13 KKKQVYKPILDNPYTNEAELWPHVREQSVVVELLLNAVLRPLRHAREl--gGAPPFEVHTGYNDVMERLG--CAESGTA- 87
gi 1730646   14 KRRQVYKPVLDNPFTNEAHMWPRVHDQPLIWQLLQSSIINKLIHIQSk---ENYPWELYTDFNEIVQYLSgaHGNSDPV- 89
gi 74606868  13 KRRQVYKPILENPFTNEAKLWPHVTDQKLVLELLEEKVLKRWKLLQDm---GNNEESITVGFNEIVDLLS---HGKDEY- 85
gi 74609622   3 KRGGRVIPVLEDPYSNEK--WPYCTPE--QLELLDTYMDKSVLRALKns-kPGEETGVVFDIAEILRVLQ---SESADV- 73
gi 74582454   7 KVKQTVKLVLRNPLSIS---WPIVDAN------TQEKLAQTLVQWLPashkDILDSKLTVGLNSVNELLErcCQNAKDVt 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74692658  88 ----LLFVCTRDgT-PAVLLSQVPLAAHVSALD----VAVVQLPCGTLARFDEHlpgtPHD---GMLLVPETAAVDPAFV 155
gi 1730646   90 ----CLFVCNKDpDvPLVLLQQIPLLCYMAPMT----VKLVQLPKSAMDTFKSV----SKY---GMLLLRCDDRVDKKFV 154
gi 74606868  86 ----MLFVCNKD-L-PSVLISQLPILCETSDHT----VTLVQLPRLSSAKFDDAf---RDVvhdGMCLVRTHAHYQ-DFA 151
gi 74609622  74 ----YVLALWND----SMLMRQLRLLVAVKN------VPLIPINKKINNKLLEHvg-dSYA---DVLLLKKTASLDQSLA 135
gi 74582454  78 qpavVFILHDQD----SMLVTHMPQLVANANFYgsskCRLVPLGFSAQALIAKKlg-lSRA---GAIAVQDDSPLWKYLK 149
                       170
                ....*....|....*..
gi 74692658 156 QKVRASVERRAIPWLEP 172
gi 1730646  155 SQIQKNVDLLQFPWLNA 171
gi 74606868 152 KMISTKVEPLSIPWLHS 168
gi 74609622 136 NLLDS-IEQPPTPFLEP 151
gi 74582454 150 DLVMN-IEEPQARWLSE 165
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