1Y56,1LVL,1EBD,4H4T


Conserved Protein Domain Family
Pyr_redox_2

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pfam07992: Pyr_redox_2 
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Pyridine nucleotide-disulphide oxidoreductase
This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.
Statistics
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Aligned: 64 rows
Threshold Bit Score: 100.085
Threshold Setting Gi: 73535574
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1Y56_A               109 VDVAIIGGGPAGIGAALELQQ-YLTVALIEERGWLGGDMWL-K--GIKQEGFNKD------SRKVVEelvgk-lnenTKI 177  Pyroco...
O50134                24 WDVIIIGAGPAGYTAAIYAARfGLDTIIITKD--LGGNMAItD--LIENYPGFPEgisgseLSKKMYdqvk---kygVEV 96   Pyroco...
ELP57807               7 LDLVIIGAGPAGLTAAIYAIR-AKLNTLVLENELVGGQIREtY--TVENFPGFNVisg-adLADKMEehaas-igvnIDQ 81   Clostr...
P52213                 5 YDIAIIGSGPAGLAAALYGARaKMKTLLL-EGMKVGGQIVItH--EVANYPGSVPeatgpsLIGRMEeqvee--fgaeRV 79   Peptoc...
Q9ZL18                 2 IDCAIIGGGPAGLSAGLYATRgGVKNAVLFEKGMPGGQITGsS--EIENYPGVKEvvsgldFMQPWQeqcfrfglkhEMT 79   Helico...
P81433                 7 KKIIILGSGPAGYTAAIYSSRaNLNPLLI-TGINKGGQLMNtN--EIENWPGDFKkitgpeLMNRMHehslk--fkteIV 81   Buchne...
O29966               170 TDVLVIGGGPGGMSAAINAGKyGAKVLLVDENPFLGGQLVKqThrFFGSAKERAGtrg-ikIAGILEeelnsienveVRR 248  Archae...
rhodo:RCAP_rcc02529  143 KSVAVVGAGPAGLACAHRLAMlGHEVTVYDARLKPGGLNEY----GIAAYKAPGGfaa-----------------reVAW 201  Rhodob...
Q46811               551 HPVAVIGAGPAGLAAGYFLARaGHPVTLFERE--ANAGGVVkN--IIPQFRIPAEliq-----------------hdIDF 609  Escher...
O67845               154 FRVAVIGAGPAGLSCAHELAKkGHEVHVY--EALPKPGGVMyY--GIPNARLDKSiie-wevKR-LEkl-------gIKF 220  Aquife...
1Y56_A               178 YLETSALGV-FDKg-EYFLvpv--vrgDKLIEILAKRVVLATG-AidSTMLFennDMP--GV------FRRDFALEVMNV 244  Pyroco...
O50134                97 IID-EVIRIdPAEcaYYEGpcnfvvktANGKEYKAKTIIIAVG-A--EPRKL---NVP--GEke--ftGRGVSYCATCDG 165  Pyroco...
ELP57807              82 FSNIEKIKL-SDDe-KIIE--------TEDVIYKVKALIIATG-A--KSRRL---PIP--EEek--lhGKVIHYCELCDG 141  Clostr...
P52213                80 MDN--IVDVdFTD--KIKVl------kGAKGEYKAKAVIVATG-A--SPKLA---GCP--GEke--ltGKGVSYCATCDA 139  Peptoc...
Q9ZL18                80 AIQ--RVSK-KGS--HFVIl------aEDGKTFEAKSVIIATG-G--SPKRT---GIK--GEse--ywGKGVSTCATCDG 138  Helico...
P81433                82 YDN--IISVeFKKk-PFFLl-------GEYNKYTCDAVIIATG-A--NPRYL---GLS--SEnk--fkGKGISTCAVCDG 141  Buchne...
O29966               249 ETR--VFGIyNGEagAYQRlnd---deGKLLRIKAKKIVVATG-AyeRTLIFennDLP--GVy----gAGGVQTLMNVYG 316  Archae...
rhodo:RCAP_rcc02529  202 LLQIGGIAVlENW--KLGRngs-----vaDLLAEHDAVFLGMGlA--GVNAL---TIP--GAehatpaTEFIAHLRQAGD 267  Rhodob...
Q46811               610 VAA-HGVKFeYGCspDLTIeq--------lkNQGFHYVLIATG----TDKNS---GVKlaGDnq--nvWKSLPFLREYNK 671  Escher...
O67845               221 FYG----YL-IGK--NITLqel---------reKYDAVFIAVG-A--GRGKL---GLP--GDhlk-gvYSAIDFLMRVNL 275  Aquife...
1Y56_A               245 WEVAPGR----------KVAVTG------------SKA---DeVI-----------QELERW---------GIDYVhIPN 279  Pyroco...
O50134               166 PLFVGKE-----------VIVVGggntalqealylHSIg-vK-VTlvhrr----dkfrADKIlqdr-fkqaGIPAIlNTV 227  Pyroco...
ELP57807             142 ALYQGKD-----------LVVVGggnsaveaaiflTKYa-rN-ITivhqf----dylqAQKYsqdelfkhkNVKIIwDSE 204  Clostr...
P52213               140 DFFEDME-----------VFVIGggdtaveeamflTKFa-rK-VTivhr---raelRAAKSIqeka-fkneKLNFMwNTV 202  Peptoc...
Q9ZL18               139 FFYKNKE-----------VAVLGggdtaveeaiylANIc-kK-VYlihrr----dgfrCAPItlehaknnsKIEFLtPYV 201  Helico...
P81433               142 FFYKNKE-----------IAVVGggntaieetlylSNFv-kK-IYlihrrnnfkaeKILIDRllki-vktkKVILHlNST 207  Buchne...
O29966               317 IKPGNMG------------LIVGsgnvgliltyqlMQAg-vNvAAiveam-----prigGYFvhaakvrrlGVPIYvRHT 378  Archae...
rhodo:RCAP_rcc02529  268 LATVPVGr---------RVVVIGggmtavdaavqaKLLg-aEtASivyrr--sqaeMPASAHeqeh-aqknGVRIVpNAA 334  Rhodob...
Q46811               672 GTALKLGk---------HVVVVGagntamdcaraaLRVpgvEkATivyrr-slqemPAWREEyeea--lhdGVEFRfLNN 739  Escher...
O67845               276 YKANEFPkkgvpvelgkRTVIIGggftavdcaitaNRLg-vE-THvvyrr--tretSSARQEewdh-lmeeGVKIHwLTQ 350  Aquife...
1Y56_A               280 VKRVEGNEKv---------Er--VIDMNNHE---------------YKVDALIFADGRRPDINPIt---QAGGKLRf--- 327  Pyroco...
O50134               228 VTEIKGTNKves----vvlKn--VKTGETVE---------------KKVDGVFIFIGYEPKTDFV----KHLGITd---- 278  Pyroco...
ELP57807             205 IRNIVGENEie------kiVvenVKTKQKTE---------------LKADGVFVYIGYEPKTEL-----FKDSINIn--- 255  Clostr...
P52213               203 IEEIKGDGIves-----avF---KNRETGEVtefv-------apeeDGTFGIFVFIGYDPKSAL-----VEGKLELd--- 259  Peptoc...
Q9ZL18               202 VEEIKGDASgvs----slsIk-nTATNEKRE---------------LVVPGLFIFVGYDVNNAVLkqedNSMLCECd--- 258  Helico...
P81433               208 IEDILGNNKgvth---lliKnknLKEKKKLK---------------IAVSGLFVAIGYIPNTDI-----FTDQLKMk--- 261  Buchne...
O29966               379 ILKAIGRKSvegaviaqldDrwqPIPGTEKE---------------IKCDFICVAVGLSPTHELL----YQAGCEMkfvp 439  Archae...
rhodo:RCAP_rcc02529  335 PVAIRKDDQgye----vefAr--TETQGGKLvqld-------dtlrIKADQIFTAIGQTLGP-------VPEGLTIt--- 391  Rhodob...
Q46811               740 PERFDADGTl---------TlrvMSLGEPDEkgrrrpv-etnetvtLLVDSLITAIGEQQDTEAL----NAMGVPLd--- 802  Escher...
O67845               351 PVEVIGNEKgev----vglKcikMELGEPDEsgrprpvpvpnsehiIECDSVIFAIGQRANPIAY----EGSGIKTt--- 419  Aquife...
1Y56_A               328 rRGYYspVLDEYH-----RI-KDGIYVAGS--AVSIKPHYANYLEG 365  Pyrococcus horikoshii OT3
O50134               279 eYGYI--PVDMYM-----RTkVPGIFAAGDi-tNVFKQIAVAVGQG 316  Pyrococcus horikoshii
ELP57807             256 kWGYI--ETDENM-----ETnIKGVFAAGDvrSKLIRQLTTAVSDG 294  Clostridium pasteurianum DSM 525 = ATCC ...
P52213               260 eTGYI--PTDDNM-----KTnVEGVFAAGDirVKSLRQVVTATADG 298  Peptoclostridium litorale
Q9ZL18               259 eYGSI--VVDFSM-----KTnVQGLFAAGDirIFAPKQVVCAASDG 297  Helicobacter pylori J99
P81433               262 -DGYI--KIKKGThgnytQTnIPGVFAAGDviDHVYRQAITSSASG 304  Buchnera aphidicola str. Sg (Schizaphis ...
O29966               440 eLGGIvpLRTRFN-----ETsVKGLYVAGDv--aGIEEATAAIMEG 478  Archaeoglobus fulgidus
rhodo:RCAP_rcc02529  392 -GGKI--EIDAQG-----RTgMAHVWAGGDcaTGGEDLTVTAVAQG 429  Rhodobacter capsulatus SB 1003
Q46811               803 kNGWP--DVDHNG-----ETrLTDVFMIGDv-qRGPSSIVAAVGTA 840  Escherichia coli K-12
O67845               420 kWGTI--EVNERY-----ETnLEGVFAGGDv-iNGGDRVVVALAHG 457  Aquifex aeolicus
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