2ZZF,1NYQ,3WQY,1TJE,2E1B,3KEW


Conserved Protein Domain Family
tRNA_SAD

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pfam07973: tRNA_SAD 
Click on image for an interactive view with Cn3D
Threonyl and Alanyl tRNA synthetase second additional domain
The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Statistics
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PSSM-Id: 336886
View PSSM: pfam07973
Aligned: 208 rows
Threshold Bit Score: 30.8746
Threshold Setting Gi: 29839437
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2ZZF_A 704 IRVVKI-EDWDVQACGGTHLPSTGLVGPIKIL-------R-------TERIQDGVERI 746 Pyrococcus horikoshii
Q7NBT5 100 VNLATVdN-HHYYLPMAQLVDNTKLVKAFNFQsvggayfK-------GDKDNLVMVRL 149 Mycoplasma gallisepticum str. R(low)
Q7V8D2 169 IKLYRH-Q-EYTDMCRGPHVPNTRHLRTFKLMkvsgaywR-------GDSNKTMLQRI 217 Prochlorococcus marinus str. MIT 9313
Q7V287 169 INLYKH-EE-YIDMCRGPHVPNTCHLRHFKLLklsgsywR-------GNSENESLQRI 217 Prochlorococcus marinus subsp. pastoris str...
Q87Q70 171 PGLYHH-EE-YIDMCRGPHVPNMGFCQHFTLLnvagaywR-------GNSDNKMLQRI 219 Vibrio parahaemolyticus RIMD 2210633
P0A8M3 170 pgLYFH-EE-YVDMCRGPHVPNMRFCHHFKLMktagaywR-------GDSNNKMLQRI 218 Escherichia coli K-12
Q8D3C0 169 LYIYHQ-E-QYVDLCTLPHVPNIKFCMFFKIQkisgaywK-------GNKKNKMLQRI 217 Wigglesworthia glossinidia endosymbiont of ...
Q883H9 169 MGLYYH-E-EYVDMCRGPHVPNTRFLKSFKLTklsgaywR-------GDAKNEQLQRV 217 [Pseudomonas syringae] pv. tomato str. DC3000
Q6L1H3 201 ATVYRE-GD-YYEFCRGPHVPSTGFIKAFKLLsiasttyN-------GEINGKRMIRI 249 Picrophilus torridus
1TJE_A 170 pgLYFH-EE-YVDMCRGPHVPNMRFCHHFKLM-------KtagaywrGDSNNKMLQRI 218 Escherichia coli
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