Conserved Protein Domain Family
TraG_N

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pfam07916: TraG_N 
TraG-like protein, N-terminal region
The bacterial sequences found in this family are similar to the N-terminal region of the TraG protein. This is a membrane-spanning protein, with three predicted transmembrane segments and two periplasmic regions. TraG protein is known to be essential for DNA transfer in the process of conjugation, with the N-terminal portion being required for F pilus assembly. The protein is thought to interact with the periplasmic domain of TraN to stabilize mating-cell interactions.
Statistics
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PSSM-Id: 336864
View PSSM: pfam07916
Aligned: 62 rows
Threshold Bit Score: 120.918
Threshold Setting Gi: 81377823
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q6MB85         11 TIHTYGGGEILQKVFvaiamlsgeggMVfPLMFLCAA-LGFGFMVCQ---L---LVTLsf-----dRF---F---THYFV 72   Candidatus Pr...
Q2LU10         30 EYYTYNGFGAVVTAFqkislifsdngYR-ALFFTVTA-LGIFIAGAA---A---YFhLlkgarfspLS---W---AWPVG 95   Syntrophus ac...
WP_011734192   28 EFYVWGGHDAVVNAFgklalifgdnaYK-SLYFVVIT-AGLFFGGVT---V---FARLlgtgsgsvTT---W---IVPTL 93   Pelobacter pr...
WP_015722889   26 EYYTYGGFNPIVQAFtrvalifsdagYQ-GLITVMTI-MGVLAGSGA---WiarAATGarv---ipLT---W---TVPVL 91   Desulfobulbus...
WP_013009906    4 dFYVYGDFTSIVNAFkmvagifssnsYK-SWITILMI-FASAAFAFH---M---NMERafg---akMNdsvW---IKRLF 69   Denitrovibrio...
WP_011733875   30 EYYCYGSFGPVVSAFkliatifgnnsYQ-SLFYTVII-SAAVFTGLAvytK---IASGgqt---siLG---W---SVPMA 95   Pelobacter pr...
WP_013506095    2 EITIYGGFNTVTGIMqqialf-fsdssL-PMVFIAMFvAGVLGAGIN---E---FYSGiqr---gkST---IvaaLITCL 67   Desulfurispir...
WP_013908536    5 pitvhGEFETMRQVLvfisslvgssaYK-GGITAFFI-LALTLTMAT---G---MFDLlfgdqrslTS---W---VKLFF 70   Thermodesulfa...
WP_045346086    5 SIHSIGDSAFLEQILiavsmitgtgdFE-KMVSIGLL-LGVLMICIQ---S---VFqg------akQI---N---LQQVL 64   Enterobacter ...
WP_011078006    4 TIYTTGSAEFLEIMLnacamitgsgdAE-DLARIGAL-IGLFLLAFQ---A---VFnn-------qAI---T---FGKAG 62   Pseudomonas
Q6MB85         73 PFLVIYTAFIIPKTTIHIEDalHKPKIYK-VDHVPRLLAHFAEIASSIGYYATCGVEKAmhtVDDvkysqt--------- 142  Candidatus Pr...
Q2LU10         96 LGICLYLGLMVPTGNITIYD--PVLNRFQtVGRIPDGIVVVAGTLNKIERGLVDIISTSgtpqnfqdy-----------a 162  Syntrophus ac...
WP_011734192   94 IGIMVYLALVVPKGTIHVYD--PVYNKNQaVGGIPDGVVAVAGILNKIERGLVDIVTTAgdpLNYqsqagg--------- 162  Pelobacter pr...
WP_015722889   92 FGAVVYLAVFVPKGSLTVYD--PVLNRFQtVGDLPDAIVFTAGALNLIERGLVDIIDTAaapDAAysrta---------- 159  Desulfobulbus...
WP_013009906   70 WGMALYSIFMVPTVTMHIYD--PVKNRYEaVGGVPLGAGMIASVTSSASRELTDIIETAgspIMSandigf--------- 138  Denitrovibrio...
WP_011733875   96 IGIVMYIAFFVPKGSLQVYD--EVMNKTElVTQVPEGVVLVAGTFNLIERGLIEIVSTSgsiGSYqtqagg--------- 164  Pelobacter pr...
WP_013506095   68 LGLALSKVFIFNTGNLVIYDr--tSNQHAiISDVPDGLRIMYRLFNTLENFFVERWYTAshhPALdyrdnan-------- 137  Desulfurispir...
WP_013908536   71 VAIFLYAAFLSGSARVALYD--DVTGRSHvQGNIPPGIAAMMAIPNWVATEFEDLITSYl-aPSLpispfayeygikmig 147  Thermodesulfa...
WP_045346086   65 VGWILYACFFGPTTTVTIED--AYTGQVRvVANVPIGVGFAGGVISNVGYTITNLFETGygvivpnv------------t 130  Enterobacter ...
WP_011078006   63 LVLVLYMMFYGPTATTVIED--TVSSQVRvVDNVPLGPAFVGSVISTVAYGITKTTEQAfstpsmt-------------- 126  Pseudomonas
Q6MB85        143 --glifgSDTALDYRRF-QLT-NP-------------DLQKDFKEFSKQCVLYdla--lgRYSLKELk-tST---DLWKF 199  Candidatus Pr...
Q2LU10        163 ggigfdmLLKASGGHLK-IR--DQ-------------YIDESLKRYTKDCLFFelqrpgtSLSVNDVtssST---DFMSQ 223  Syntrophus ac...
WP_011734192  163 --kgflgLAQLTSIPLS-AV--DS-------------NLDASLRRYVRDCVSYalmnpnaNLTVDELrktTT---NFVSS 221  Pelobacter pr...
WP_015722889  160 ---ggigfKALEAVKGS-TPK-NN-------------HARTSMIRYVKDCVTFelmrpgtTLSLDDLrntST---DFLAN 218  Desulfobulbus...
WP_013009906  139 -gdgfelLAASSAMGQIgNMN-DH-------------FLAKSVYDYIEKC-FRqay-angDITDKDIw-tSN---NLLES 197  Denitrovibrio...
WP_011733875  165 --kgflgLYALTTRPLS-SKT-NI-------------YLEQNLNYYLKDCVTFavnnpasNLTIDELr-rTPa--SFSTS 224  Pelobacter pr...
WP_013506095  138 -gigfdmFLNASKVGGI-P-N-DP-------------LINRSLQRYWTDCVTFalkvpasNLTMAEMm-hGDapgGLIAS 199  Desulfurispir...
WP_013908536  148 esysgemATALANII-------DP-------------QMWESAGNYVRDCValla--areASYAKKLy-sGD---NPYRA 201  Thermodesulfa...
WP_045346086  131 eshfsetLKLLNDVRRR-AYDtGVftalnsangggyvDVRRSWNNYIRECTLTkvd--lnLMSLDELm-nRS---T-DSA 202  Enterobacter ...
WP_011078006  127 dyglfssLSTLSKVRDA-LRNpMAldgfqnyrksdgwDLPRSVNEYMTFCSLNpval-rtdKTLTDLy-rSP---GWAQV 200  Pseudomonas
Q6MB85        200 LKertstlgmiyycp-ptakggtkkeaceYLTCRQALEkfeplfskekayyakqeig--------------------knl 258  Candidatus Pr...
Q2LU10        224 YAqaanpavftv-------wysesdrtgtTMSCADAWTnlqgyfsdplnmgdtirfacanagfnadnageltkcteiisn 296  Syntrophus ac...
WP_011734192  222 LDkainpaiwtv-------yynaanpqgqTLTCTDAWT------------------------------------------ 252  Pelobacter pr...
WP_015722889  219 LSqavnpsvftv-------yydsahpegaTMSCTQAWN------------------------------------------ 249  Desulfobulbus...
WP_013009906  198 FSlnyrvfssvi--------ydnanpegvLYECADAYT------------------------------------------ 227  Denitrovibrio...
WP_011733875  225 LVkaanpaiytl-------ylsptdsqgdSLNCTDAWT------------------------------------------ 255  Pelobacter pr...
WP_013506095  200 FGkaqhpmlqtqf-----yqsndthksgtWMSCRDSWD------------------------------------------ 232  Desulfurispir...
WP_013908536  202 WSeainyffytytsldsngnplppgtpneSVSCKEAWDrldkyfqntrwqevvdkfctlmhygtda--tsisacrdtmst 279  Thermodesulfa...
WP_045346086  203 LRfnsqlygtrl-------ylstanpdgaDYTCTDGWVaistatanlsspvvvdalnsllgidt------stgdnaltkl 269  Enterobacter ...
WP_011078006  201 LSnqtssmfiy----------vydgtagtMKSCAEARSflnahlqnvytdvledilqkgfseevkt-nrmttgiqvqaat 269  Pseudomonas
Q6MB85        259 pltfqalthikqdsqT-------------L--------I--------------------------------SQ------- 278  Candidatus Pr...
Q2LU10        297 yasyveggaftipapN-------------F--------M--------------------------------RQ------- 316  Syntrophus ac...
WP_011734192  253 ---------------N-------------IksaltpasL--------------------------------TK------- 265  Pelobacter pr...
WP_015722889  250 ---------------QlrplyaatsnygeA--------I--------------------------------RK------- 267  Desulfobulbus...
WP_013009906  228 ---------------N-------------Ist----rlM--------------------------------SP------- 236  Denitrovibrio...
WP_011733875  256 ---------------A-------------I--------VadmtpaelsgnmetvctelgydvsdaaqfnqcKQ------- 292  Pelobacter pr...
WP_013506095  233 ---------------Nir----------pY--------I--------------------------------TNpanftqs 247  Desulfurispir...
WP_013908536  280 vfsryvingltvspeN-------------I--------A--------------------------------KN------- 299  Thermodesulfa...
WP_045346086  270 tdslqamgatttssiD-------------Y--------L--------------------------------KA------- 289  Enterobacter ...
WP_011078006  270 dqaiqslalssksaqD-------------Y--------V--------------------------------LT------- 289  Pseudomonas
Q6MB85        279 -----------------------------Q----------------------L------------------MM------- 282  Candidatus Pr...
Q2LU10        317 -----------------------------V----------------------Y------------------MA------- 320  Syntrophus ac...
WP_011734192  266 -----------------------------N----------------------I------------------YSvctnlgy 276  Pelobacter pr...
WP_015722889  268 -----------------------------V----------------------CskayfdpdnsaelttcrnLI------- 289  Desulfobulbus...
WP_013009906  237 -----------------------------T----------------------F------------------TE------- 240  Denitrovibrio...
WP_011733875  293 -----------------------------AvtdakdtvglsaltldefvkqvF------------------IK------- 318  Pelobacter pr...
WP_013506095  248 rdricasagvdindplqlqsceqkinqhiQ----------------------F------------------IS------- 280  Desulfurispir...
WP_013908536  300 -----------------------------V----------------------F------------------AG------- 303  Thermodesulfa...
WP_045346086  290 -----------------------------A----------------------V------------------LE------- 293  Enterobacter ...
WP_011078006  290 -----------------------------S----------------------L------------------IA------- 293  Pseudomonas
Q6MB85        283 ------------H------------VLADS-------------------------------------------------- 288  Candidatus Pr...
Q2LU10        321 ------------E------------VLNDMl------------------------------------------------- 327  Syntrophus ac...
WP_011734192  277 dvtdaaavtqckT------------VLNNV-------------------------------------------------- 294  Pelobacter pr...
WP_015722889  290 ------------N------------ATMTF-------------------------------------------------- 295  Desulfobulbus...
WP_013009906  241 ------------N------------VMYKFcsqsgfnvsntseyqackdkftglvdsfatdigfsitlsnyvasafiarq 296  Denitrovibrio...
WP_011733875  319 ------------N------------RLDSS-------------------------------------------------- 324  Pelobacter pr...
WP_013506095  281 ------------NgqvtgglghfnaLMNLA-------------------------------------------------- 298  Desulfurispir...
WP_013908536  304 ------------K------------VFYSFlssld--------------------------------------------- 314  Thermodesulfa...
WP_045346086  294 ------------P------------LYYEAa------------------------------------------------- 300  Enterobacter ...
WP_011078006  294 ------------P------------IFNDSr------------------------------------------------- 300  Pseudomonas
Q6MB85        289 ---FSpe---------------------------kFAQERAHLQQNST-----YQAAGFTAAKGIVYMRVLFEALIYTSF 333  Candidatus Pr...
Q2LU10        328 --lDAnp--------------------------dlAVKGLASRSIMTG-----GLGMGIVANEWLPVARAVITAVAIGLI 374  Syntrophus ac...
WP_011734192  295 ---NSgtglgaasiddflrq-ayisqrleeifrsgNATGATNYQFLLN-----ASGAMKAANEWLPILKAALTAIAVGLL 365  Pelobacter pr...
WP_015722889  296 ---ATgtavpperllqqrqiaeilysfyfqddpetAVLMESDRRITAS-----GLGVGLTMNEWIPVIRAILTAIAIGVI 367  Desulfobulbus...
WP_013009906  297 ylmGGvna------------------------gtqNAIDIAKSMATAA-----NTVAGGVADEYIPKLQGMIITILIATF 347  Denitrovibrio...
WP_011733875  325 ---YQsgn------------------------tqvV----SNYQFLTN-----VSGSMKSFNEYYPVLRGVLTAVAIALI 368  Pelobacter pr...
WP_013506095  299 ---RStfe------------------------vtkIGGDHAINRFIQQdftvkGIGAIMGSSGYMGEARYAMFAIVGAMS 351  Desulfurispir...
WP_013908536  315 -------------------------------psveAARIASFARAQAE-----LSGKGIVAQEWLPVMKTIFYILACSLI 358  Thermodesulfa...
WP_045346086  301 --aGRyqdlq--------------------dygsaLMVNQAIQQRNTQ-----WAAEQSMFMTVVRPMLTFFEGFIYAIT 353  Enterobacter ...
WP_011078006  301 --vDAmnhwq--------------------eqraaMALRESLNQQEIQ-----WAGKGDSFKHYMRPMIAFFEGMLYAMT 353  Pseudomonas
Q6MB85        334 LFVLPLSLLPS-GIKILMNWAWSVVWIQFWPPFYAILNYLASIVAKHTt-----AgiadglaekglsiftsvGIENFAND 407  Candidatus Pr...
Q2LU10        375 PILVIFIPTPL-AGKALGLVAGMFIWLTAWGVTDAITHGIATDYAYGVfeyvrqNalgf---------aavmNMPDASLK 444  Syntrophus ac...
WP_011734192  366 PFLALFIPTPLiG-KAVGIIAGFFIWLTAWGVTDAIVHQFAVDYANQAy-----Etvrqnkl----gmdalyFFPDQTVK 435  Pelobacter pr...
WP_015722889  368 PFLVLFLPTPIvG-KAASVLLGFFVFLSTWGVTDAVIHGAAMDYAARGf-----Eevrqsnl----gvyalaALPSVSTK 437  Desulfobulbus...
WP_013009906  348 IIVALFVYMAP--VDAFKWYIGMWIWVIMWFVVDAILNVNVQAHAYEVf-----Rdirstgv----glnsmfYTGSDTLK 416  Denitrovibrio...
WP_011733875  369 PILIIFLPTPMsG-KIASILFGFFIWLTAWGVVDAILHGFAMEYANSVf-----Sqvrnegl----gldalyFFPNASVK 438  Pelobacter pr...
WP_013506095  352 CVLMLLWPTPVfG-KAFAGIIYLWGFIFFWAIGDAIAHKIAVDRAFDLy-----Aelratggt--igintlfHIPSETAK 423  Desulfurispir...
WP_013908536  359 PLALIFIGT---GTGPVKFLAGIFLWWAVWCGMDALMYCLWISRADGIfqv-vsDgarlg-------lhgleELWFLSSK 427  Thermodesulfa...
WP_045346086  354 PIIAFIIVMGSfGLQLAGKYVQTILWIQLWMPVLSIINLFVHTAASNEmsslsagg--------lnsmyalsSTGDVLQH 425  Enterobacter ...
WP_011078006  354 PFLAFALLLGGpGLSILGKYLVLPLAVGLWMPLLSIVNAFTLWYAGSQmeavfnGydptgsg---famlqlmDIDKAIGK 430  Pseudomonas
Q6MB85        408 TFALAGYL----T----L-S----VP----FLSYV---LLQ-GGLSQFVQLAGTLTSPAQSAA 449  Candidatus Protochlamydia amoe...
Q2LU10        445 ALSMFGLI----R----TsG----IM----LATVItgmLVRfGGH-ALAMMAGTISGTVQSQG 490  Syntrophus aciditrophicus SB
WP_011734192  436 ILGMFGTL----R----M-SgmmlAT----VITGM---LIRfGGH-AMAMMAGSLGSQVQSAG 481  Pelobacter propionicus
WP_015722889  438 MLAMFGVI----RsagiM-L----AS----LFSMM---LIRfGGH-ALAMLAGNLSAIVQGAG 483  Desulfobulbus propionicus
WP_013009906  417 VLAMYSNA----R----W-I----SMslasVISFG---IIKmGGSAAFASMTSALGQQYRSSA 463  Denitrovibrio acetiphilus
WP_011733875  439 ALAMFGTL----R----M-SglvlST----ALTGM---LVKfGGNAI-TQMGSSLQGHIAAAG 484  Pelobacter propionicus
WP_013506095  424 ALGVFGQMraysM----L-V----AT----IITGF---LFK-VSSPGMAQLGSRIGGAMSdig 469  Desulfurispirillum indicum
WP_013908536  428 AFALLGGM----R----SfG----FM----LAGAFvytVFRfGGS-VMAHFASAMVGSLSSGA 473  Thermodesulfatator indicus
WP_045346086  426 WIATGGML----A----A-A----TP----VISLF---IVT-GSTYAFTSLASRISGSDHVDE 467  Enterobacter hormaechei
WP_011078006  431 ALGIGGLL----A----A-S----VP----PLALF---IVS-GSAMVANSIMSQMTAGEKFKS 472  Pseudomonas
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