Conserved Protein Domain Family
Auto_anti-p27

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pfam06677: Auto_anti-p27 
Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)
This family consists of several Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) sequences. It is thought that the potential association of anti-p27 with anti-centromere antibodies suggests that autoantigen p27 might play a role in mitosis.
Statistics
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PSSM-Id: 310936
View PSSM: pfam06677
Aligned: 120 rows
Threshold Bit Score: 36.7581
Threshold Setting Gi: 74858559
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 74684927  116 SISNLLLKGYSLLGENCP--NpsCrGIPLVGYPrkadgskdGR-KMCVSCG 163
gi 541049034  61 KMGDLLLRGYTMLNAYCD--I--C-SGILMEDRq-------GV-RVCVTCD 98
gi 353236822  10 sLGEYLLKGWTLTNDPCP--K--C-FVPRMRAPays--nepKN-LICVNCD 52
gi 298715132 125 aMGEKLLQGWTMLAEECE--TagC-CFPLMRDRg-------RV-TRCVACD 164
gi 754345637  15 KLGEFLLRGHRMQNAYCL--D--C-NTVLMLDLs------tNR-EHCVHCD 53
gi 449550115  10 KLGEYMLKGWILTDDICS--Q--CaKIPLMRAPn------pPVsWFCAACD 50
gi 599402588  11 iLGRYMLQGWTLTDVNCPksD--CiGCPLMRSKa-------GS-EFCARCD 51
gi 953442587  11 TLGHYMLQGWTLSDRICS--KpgCpGVPLMTKA--------SQ-QFCARCD 50
gi 597926720  10 KLGEYMLKGWILTDTSCP--TpgC-RIPLMRSPngt---tpQT-YFCANCD 53
gi 527294518  10 KLGEYMLKGWVLTDKSCP--K--CsRVPLMRSPsg-----pTV-HFCANCD 50
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