3JCR,5GAN


Conserved Protein Domain Family
PRP1_N

?
pfam06424: PRP1_N 
Click on image for an interactive view with Cn3D
PRP1 splicing factor, N-terminal
This domain is specific to the N-terminal part of the prp1 splicing factor, which is involved in mRNA splicing (and possibly also poly(A)+ RNA nuclear export and cell cycle progression). This domain is specific to the N-terminus of the RNA splicing factor encoded by prp1. It is involved in mRNA splicing and possibly also poly(A)and RNA nuclear export and cell cycle progression.
Statistics
?
PSSM-Id: 336399
View PSSM: pfam06424
Aligned: 123 rows
Threshold Bit Score: 93.8473
Threshold Setting Gi: 149239466
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3JCR_G         13 APLGYVPGLGRGATGFTTRSDIGPARDaNdpvddrhappgkrtvGDQmkknqAADDDDEDLNDT-NYDEfng-yagSLFS 90   human
XP_001386957   11 PPPGYISGIGRGATGFTTSADTGSLQPg---------------fTIE-----NGEESDDNLAGEigd-------egAILA 63   Scheffersomyc...
XP_007375886   11 PPPGYIPGIGRGAVGFVTSVDTfnk-----------------glAVT-----QAEEDEEEVYDS-Ngan-----eeGILA 62   Spathaspora p...
XP_018213149   11 PPPGYIAGIGRGATGFTTQADLGSSRRlPags---------falEDE-----NNVDDDGRFLDA-DNDd------tGRFG 69   Ogataea polym...
XP_001483052   11 APKGYVAGIGRGATGFTTSADTGAVRIeDdiedd-----------------gpkiDDDS-----------------GLLA 56   Meyerozyma gu...
XP_002682714    5 PPPGYVAGIGRGATGFTTRSDIGPARLpSrftq-------pqgsSSN-----STTEEENEQETNqTFDEwsg-yggNILG 71   Naegleria gru...
XP_006687813   11 APAGYVAGVGRGATGFVTSADAGGLRSvRp-------------fEPS-----DSEDDNGDNNSL------------GLLG 60   Candida tenui...
CCE73277       11 APDGYIPGVGRGATGFTTSADSGGlafq-------------qglVLE-----SASEDDEAQNTNnd---------dGILG 63   Pichia farino...
XP_002493977   11 PPPGYVAGLGRGATGFTTQADVGTGRIvPa--------------SFS-----DEESDDEDFVDDrFKDAdetenglNGFK 71   Komagataella ...
XP_011276801   11 APIGYIAGIGRGATGFTTRADVGAGRLpP---------------------------QQRDIGSD-DEDNyqdvdedGLLG 62   Wickerhamomyc...
3JCR_G         91 --S-G-P-YEKDDEEADAIYAALDKRMDERRKERREQREKEEIE-----KYR----------MER-----PKIQQQFSDL 145  human
XP_001386957   64 --S-G-KnRDKEDEEADQIYEEIERKLQRRKVLKEEAVSEAENQ-----SYE--------------------IKSKFSDL 114  Scheffersomyc...
XP_007375886   63 --T-T-R-QDADDEEADRIYEQIDQRLQS--------KQKQEIT-----TVE----------KDN--------KVNFTDL 106  Spathaspora p...
XP_018213149   70 --S-----VSDDDGDADRIYDAIEAKLQRKKARPRKRAQKNALE-----DENkvqveeisigQSI-----RTIGEEFKEY 132  Ogataea polym...
XP_001483052   57 --RrG-K-GDAAEEEADKIYEDIERRLLEKKRKKNEQLVE-----------R----------PPS-----DDPVSQFVDL 106  Meyerozyma gu...
XP_002682714   72 rvT-G-V-EDEEDKEADSIWSAISQRMENKKKRKNVTENENQTSkyakySVL----------TSSldsqkPKIAATFSDI 138  Naegleria gru...
XP_006687813   61 ------G-QSKDDEEADRVYDEVERRLQKRHKNTSQLEVVQQDE-----E--------------------NQIAQQFTDL 108  Candida tenui...
CCE73277       64 --S-KkH-QDKDDLEADKVYEEIERKLMKKKGNKEPDEVTKKDDs-------------------------VGMKEQFSDL 114  Pichia farino...
XP_002493977   72 ------E-KDDSDNEADQVFAEIEERLKRRNKRKNEVQEDEEPL--------------------------DEIKKNFQEL 118  Komagataella ...
XP_011276801   63 ----DkT-LNKEDEEADEIYQEIDNRLKNRNKRRISPNDDATTT-------G----------NNGnddnlTKISNQFVDL 120  Wickerhamomyc...
3JCR_G        146 KRKLAEVTEEEWLSIPEVGDARNK 169  human
XP_001386957  115 KRSLSSISAEQWEALPEVGDITRR 138  Scheffersomyces stipitis CBS 6054
XP_007375886  107 KRDLARVSEEQWELLPEAGDITRR 130  Spathaspora passalidarum NRRL Y-27907
XP_018213149  133 KEKLSEVSAEDWLNLPDSGDFTKR 156  Ogataea polymorpha
XP_001483052  107 KRDLSQVTRDQWAALPEVGDLTRR 130  Meyerozyma guilliermondii ATCC 6260
XP_002682714  139 KEELKYLSKEEW-NIPEVSgsavn 161  Naegleria gruberi strain NEG-M
XP_006687813  109 KRHLAHVSQDEWANLPEASDFTKR 132  Candida tenuis ATCC 10573
CCE73277      115 KRALTNVSDFEWQNLPEAGDFTRR 138  Pichia farinosa CBS 7064
XP_002493977  119 KKNLTSISEEEWFNLPESGDLTRK 142  Komagataella pastoris GS115
XP_011276801  121 KKNLSSISEDQWANLPEVGDLTKR 144  Wickerhamomyces ciferrii
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap