Conserved Protein Domain Family
CobT

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pfam06213: CobT 
Cobalamin biosynthesis protein CobT
This family consists of several bacterial cobalamin biosynthesis (CobT) proteins. CobT is involved in the transformation of precorrin-3 into cobyrinic acid.
Statistics
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Aligned: 62 rows
Threshold Bit Score: 138.883
Threshold Setting Gi: 123614520
Created: 4-May-2019
Updated: 18-Jul-2019
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFG84002                18 TARAERFKRATVGAVRAVGGNAATEVMFLNGPvapgVSVVGA--QVRLPQPAVGMSDADMTRLRGAADAAALRVRHHNEA 95  Komag...
jgi:Hbal_0789            5 ADQHEIFRSALAVTTAAMVADKNVEVGFSADG----GHASGD--RIVLNSPPRKLTAASAALARGEADMLALKKRHHDAK 78  Hirsc...
Q0BWH9                   5 TSPQELFKQALAATTKAMSAERDIEVGFGPDV-----GDQGT--RLVLRTPPVELAPELAARIRGEADALALRRAHHDAD 77  Hypho...
Q3V828                  10 LKEVQDFRDCVKRVVAMLSGK-QIPVAERGNEayvrYNRRGEpvLVNIPSIPDDASPTLMNAVRGFLDHEVAHILFTDPK 88  Yersi...
Q2G5P8                   4 ESPLDRFRSVLTGTARAISHDPEVEVAWTADA----PVQSGS--SMRVPMPGRALPAEQVAEARGHADSMALRLRHHNAA 77  Novos...
CCA93555                 4 ETPADRFKSVLAGASRAIAHEKEIEVNWTADA----PSSTGG--TFRVPMPGRNLPRGAAMQARGYADSFALKVRHHDDR 77  Novos...
Q2N909                   4 ESPLDSFKRALTGTARALAREPEIEVAWSADS----PSAQGR--NFRVPLPGRNLPPEQAAEARGFADSFALKLRHHNLK 77  Eryth...
BAI94941                 4 rSPLDAFKDVLSGAARSIARDAEVEVGFTADT----PHMAGK--AIKVPTPGRNLPADQVALARGYADANALRLRHHNAK 77  Sphin...
PRJNA213647:NX02_25810   4 rSPLDDFKAVLGGAARAIAREPEVELTFTADA----PLQSGR--HMKVPMPNRSLPAEQVAEARGFADGFALRLRHHDAA 77  Sphin...
ELS:G432_05690           4 QTPLEAFRQVLGGTARALSHEPEAEVGYAADA----PQAYGK--AIKVPMPARSLPAEQVAEARGFADGAALRLRHHNTA 77  Sphin...
EFG84002                96 VHAAAQPDAGE-AREIYDALEQARVESVGARYMSGMAANLQA---RLAQECAEAGFDDAGG-----GREMPSAMAFGLLA 166 Komag...
jgi:Hbal_0789           79 AFSANMPESEE-AVAIYEAAERARIDSIGAKAMDGVASNLDA---VLEERCERAEFMRIQE-----RTKISQADAIEFLL 149 Hirsc...
Q0BWH9                  78 AHLANRPQGDI-PRRVYEAAETARIESLGANAMAGTAGNLEA---VLDFRCRSTNFGMGAE-----DPDAVLAPALEFLL 148 Hypho...
Q3V828                  89 VAMKMRERGKApSTGLWNALEDVFIERRMGQVFNGTRRNLLAtqnLVIDKYFKGKVSEAVSichgnQRELFLKFFLCPVV 168 Yersi...
Q2G5P8                  78 LHGRNAPSEAL-ARACYDAVEQVRYEALGSNAYAGMRGNLDA---AVSMRMASDPISRAAK-----PEDVPLPTALALLL 148 Novos...
CCA93555                78 LHQRHAPAEPS-ARACYDAVETVRYEALGSNRYAGMRDNLDA---SLEARIASDPISRAES-----RDQVPLQSALALML 148 Novos...
Q2N909                  78 LHEANAPSDPV-ARACYDAVEQVRYEALGASGYEGIADNLDA---AVELRTASDPIARAQN-----DGDVPLQSALGLML 148 Eryth...
BAI94941                78 VHNSAAPADAT-ARAVYDAVEQARVEAIGSRAMEGVRANLNH---ALDLKLKSDPIRRARS-----ADEVPLSTALALKV 148 Sphin...
PRJNA213647:NX02_25810  78 LHARGAPSEAV-ARSVFDAIETARVEALGARSMAGVRANLGQ---ALDLKIRTDPITRARA-----RDEVPLSTALQLIV 148 Sphin...
ELS:G432_05690          78 LHARNAPAEAV-ARAAFDAVEQARVEAIGSRAMEGVRANLAH---ALDLRLKSDPLVRARS-----RDEVPLSSALGLLV 148 Sphin...
EFG84002               167 RA---------------RMTGQPVPASMQMTMQRWQDELPAAVLQALDAMVARQDSQVDFARAARQLLVACD------LI 225 Komag...
jgi:Hbal_0789          150 RE---------------RLTGKPLPSAAEHVADFWRADLEKRASGSLEALEKAMSDQSKFADAVRRLLTDLD------MS 208 Hirsc...
Q0BWH9                 149 RE---------------KLTGRPLPESAKRVADVWREKVEANAGKALDALTGQLHDQAEFARTIRSIIRDLT-------- 205 Hypho...
Q3V828                 169 RAwdgqspfidfmeehwHLIDKPVALLKEHGIDV------------AVRNMSNTEDCVKVAAAIAQIMQDMKdkpegkLP 236 Yersi...
Q2G5P8                 149 RE---------------KLTGQVAPASTQTGMAMVRSWIESKVGNDFEGLALSLDDQRAFQQLALDMLQHLD------LT 207 Novos...
CCA93555               149 RE---------------KLTGQPIPEIARPGVDMIRDWIEEKAGGDIEALADSIGDQQAFQNLSLDMLQHLE------LT 207 Novos...
Q2N909                 149 RE---------------QLTGKPIPERARAGVELVREYIESRTGSDFEDLAGSLEDQKAFQSLALDMLRHLE------LT 207 Eryth...
BAI94941               149 RE---------------RLTGQAAPKDVRAGLAMVDQWIEDKAGADLDALAMAIDDQRAFQKLTSAMLEHLQ------LI 207 Sphin...
PRJNA213647:NX02_25810 149 RE---------------RLTGEAPPAAAEPGLAMVRQWIEDKGGADLDALGLVADDQGAFARLATRLLEDLE------LV 207 Sphin...
ELS:G432_05690         149 RE---------------RLTGQPVPESARQGLALVRDWIEEKAGHDLDALGLALDDQAAFARLATRLLEDLE------LV 207 Sphin...
EFG84002               226 eqEIDPQAEDEDGSATAQSDESDASDApeepnpqEQDSPAEEEAPGLQMQMSQGTGMGEDe-----------------QD 288 Komag...
jgi:Hbal_0789          209 --DEISPAEESEDQGEEVEDAEDTDEAed----qTENSGDEQSESQGSEEFDEEEGESDT-------------------- 262 Hirsc...
Q0BWH9                 206 ----ASDLPGDEAESEDDAPSEETDEQqnq--sgDDDTQTEEQMGASAEQLEAGETEDLE------------------GE 261 Hypho...
Q3V828                 237 elKSSAKKPSKSKDESEETPESGDDPShsesapkRTKGEDDDKEEQEDDASEEEDSGDSDlpdsldkdlpihdkeisdTE 316 Yersi...
Q2G5P8                 208 ------QSASDQDEDTEEDEGEQQEDEge----eEPSTSDDQEQQPSEVAGDTSEGDEDSe-----------------SE 260 Novos...
CCA93555               208 raEEIEQPPEDSDDLDGDDETEQD----------EDGADAGEEQQPSEMAAEPSQGDDEGe-----------------SE 260 Novos...
Q2N909                 208 -------DPTDQPDSADNEDGEDEDGQdeqedesDDETGGDEQPSPAEMAGEQTEGDAEG-------------------E 261 Eryth...
BAI94941               208 ----DADVPPETDDSEPQEEGEEEEQSqed--gdSGEDQAGDSDALAEARAEDQGGDTED------------------GE 263 Sphin...
PRJNA213647:NX02_25810 208 ---EGELTPDDDEGGEDQDGGEDDESDdq---tdDADENEGGAEGDVEMRAEPQDGEQQD------------------GE 263 Sphin...
ELS:G432_05690         208 ---EGEMTPDDEQEAGEEGEGDDQDEGedg--edQQDDGSGQSDAPMEARAEASEDAEDD------------------GE 264 Sphin...
EFG84002               289 NGEQNGAASGSEEA 302 Komagataeibacter hansenii ATCC 23769
jgi:Hbal_0789          263 ESESAMAMEAEADM 276 Hirschia baltica ATCC 49814
Q0BWH9                 262 EANVSVDQDADLDA 275 Hyphomonas neptunium ATCC 15444
Q3V828                 317 SKYTEAGEDESGDT 330 Yersinia pestis
Q2G5P8                 261 QEVEQNDDAADADM 274 Novosphingobium aromaticivorans DSM 12444
CCA93555               261 SEGEASDDMQEAEE 274 Novosphingobium sp. PP1Y
Q2N909                 262 AETEAGEEVADGEL 275 Erythrobacter litoralis HTCC2594
BAI94941               264 TEYSDEFDADSEEg 277 Sphingobium japonicum UT26S
PRJNA213647:NX02_25810 264 SDSQQDDAEGDSDA 277 Sphingomonas sanxanigenens DSM 19645 = NX02
ELS:G432_05690         265 SVDMDEDSLSEMES 278 Sphingomonas sp. MM-1
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