1Q8R


Conserved Protein Domain Family
RusA

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pfam05866: RusA 
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Endodeoxyribonuclease RusA
This family consists of several bacterial and phage Holliday junction resolvase (RusA) like proteins. The RusA protein of Escherichia coli is an endonuclease that can resolve Holliday intermediates and correct the defects in genetic recombination and DNA repair associated with inactivation of RuvAB or RuvC.
Statistics
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PSSM-Id: 336227
View PSSM: pfam05866
Aligned: 91 rows
Threshold Bit Score: 54.1688
Threshold Setting Gi: 504239075
Created: 26-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1Q8R_A        12 PSNNRYYRH-----NRGr--------tHVSAE-------GQAYRDNVARIIKNAM-L--DIGLA-------MPVK-IRIE 60
gi 123161363 157 PKARPRVTA-----NGT----------YLPSR-------YRIWRNQAEVEIYRQVsKl-NLEVS-------LPIQrAAIS 206
gi 503126651  12 SKSNFKLSN-----KSGq--------aWLPHKgky--skYAAYENYIAGIINQEYf---GPPLE-------ENLI-TILK 65
gi 524362232  15 SKSNFKLHN-----KDGr--------aILPYNtgkahdkYALYEEEIAYYARSQNp---TTILE-------ESLI-AILK 70
gi 493668718 164 PKARPRVTS-----NGT----------YLPPR-------YREWRNRAEVELYRQIsEr-NLTNR-------FPIRrAAVT 213
gi 504964731 217 PKARPRVTS-----NGT----------FLPKR-------YREWRLRAEGEIIMQVnQm-NPLPQ-------LPIErASVR 266
gi 504239075  13 pSINALYFT-----TKFgk-------rIRTKK-------AKEWFAAAEEIIAGAMeDq-GWETT-------EGTK-VVID 64
gi 502515786  10 pSVNHAYRTyvhpqTGQri-------rVLTSK-------AQKFRRDAAYLALRWRqEtgWTMPQ-------PGTK-VVLR 67
gi 159894191  11 pSINSQYVT-----VGNr--------rVLSRE-------AQAFKRQVKRQLALLQqRd-TISEQflalahqGYIA-LFLD 68
gi 524088042  11 pSVNHYLGY-----RAIikdgkplavsYVTPE-------TIRYKSKLREYIAEEVeKq-HWTLKpn---ktQHFY-VDTV 73
                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
1Q8R_A        61 CHMPD--RRRRDLDNLQKAAFDALt--KAGFWLDDAQ-VVDYRV-V--------KMPVTKgGRLELTI 114
gi 123161363 207 ISFCGkhRTNSDLDNLAGACLDALtlnGAGVLQDDRL--------ScipklnieYIPHIKkIGVWIEI 266
gi 503126651  66 LYFPN--KRMGDIHNYPKSICDGIe--KSGIILNDKQ-LKPFLIl---------DYIDKDnPRVEIEL 119
gi 524362232  71 VYYKSe-KRHPDTANITKSIFDGIe--KSGLIVNDAQ-IRRIITe---------EYYDKEnPRFELEf 125
gi 493668718 214 IRLFGnhRTNSDIDNLAGACLDALtlqGAGVLMDDRL--------SclpqlrveFIPDLPkTGVWIDI 273
gi 504964731 267 IILRGkhR--GDGDNAIGSVCDALv--GAGIFSADSL--------KqipfgswrHIPDGE-TGVKIQI 321
gi 504239075  65 IMTYWpdARKRDVDNQGKAIFDALe--HAGVFDNDRWaLPRYID----------FDIDRQnPRVECVI 120
gi 502515786  68 LWYFWpsRRRMDTHNREKVLLDAL---EGVLYPEDRWvLIQEMD----------FEVDRKrPRLEIEV 122
gi 159894191  69 FYFETp--lRRDLDGGLKITQDSI---CTSLGINDNR-VVDIHLvK--------RIDPLH-PRLEVEL 121
gi 524088042  74 FYFDRv---dRDSNNYFKVLLDAIt-eTKLIWMDDNVaLERVNR----------IYYDAKnPRIELTI 127
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