Conserved Protein Domain Family
Lycopene_cycl

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pfam05834: Lycopene_cycl 
Lycopene cyclase protein
This family consists of lycopene beta and epsilon cyclase proteins. Carotenoids with cyclic end groups are essential components of the photosynthetic membranes in all plants, algae, and cyanobacteria. These lipid-soluble compounds protect against photo-oxidation, harvest light for photosynthesis, and dissipate excess light energy absorbed by the antenna pigments. The cyclisation of lycopene (psi, psi-carotene) is a key branch point in the pathway of carotenoid biosynthesis. Two types of cyclic end groups are found in higher plant carotenoids: the beta and epsilon rings. Carotenoids with two beta rings are ubiquitous, and those with one beta and one epsilon ring are common; however, carotenoids with two epsilon rings are rare.
Statistics
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Aligned: 9 rows
Threshold Bit Score: 410.27
Threshold Setting Gi: 81721284
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q8LJ81 119 DLVIIGCGPAGLSLAAES-----AKKGLNVGLI--GPDLPFTNNYgVWEDEFKDLG------LESCIEHVWKDTIVYLDG 185 Japanese rice
Q38932 110 DLVVIGCGPAGLALAAES-----AKLGLKVGLI--GPDLPFTNNYgVWEDEFNDLG------LQKCIEHVWRETIVYLDD 176 thale cress
O65837 107 DLVVIGCGPAGLALAAES-----AKLGLNVGLV--GPDLPFTNNYgVWEDEFKDLG------LQACIEHVWRDTIVYLDD 173 tomato
Q9RI55  10 DVLVIGGGAAGLSLAHRLt---eNGTAPAMTLVepPDGPLRPAER-TWCYWGAAADg-----LEEAVGASWSVLRLHGAD 80  Streptomyces coelicolor
Q82PA6   5 DVAIVGAGAAGLSLAHRLacpvrGAPRISVVLLeaPPGPLRPPRR-TWCFWERGPGr-----YDAAVTASWQRLRVRAPG 78  Streptomyces avermitilis
Q93CI8   2 DIVFVGAGLANCLMAARLa---aQRPGLHMLLLeaGESV--GGNH-SWSCHDSDLTaaqrafLAPFQSYLWAGHGVHFPA 75  Xanthobacter autotrop...
Q9KIX3   6 DVIVIGGGLAGCLIALRLt---dARPDLRVVIIegSASI--AGNH-TWSFFGTDISsdqhawLGRLVGHRWPGYEVRFAE 79  Bradyrhizobium sp. OR...
Q9M424  83 DVIIIGAGPAGLRLAEHV-----SKYGIKVCCVdpSPLSMWPNNYgVWVDEFENLG------LEDCLDHKWPMTCVHIND 151 potato
Q38933  84 DLAIVGGGPAGLAVAQQV-----SEAGLSVCSIdpSPKLIWPNNYgVWVDEFEAMD------LLDCLDTTWSGAVVYVDE 152 thale cress
Q8LJ81 186 NKPIMIG---RAYGRVHRDLLHEELLRRCY-DAGVTYLSSKVDKIMESPD-GHRVVCCEGDR--EVLCRLAIVASGAASG 258 Japanese rice
Q38932 177 DKPITIG---RAYGRVSRRLLHEELLRRCV-ESGVSYLSSKVDSITEASD-GLRLVACDDNN--VIPCRLATVASGAASG 249 thale cress
O65837 174 DEPILIG---RAYGRVSRHFLHEELLKRCV-EAGVLYLNSKVDRIVEATN-GQSLVECEGDV--VIPCRFVTVASGAASG 246 tomato
Q9RI55  81 GGSVTVDpapFTYRMVRSADFERMVHGRLArTDGARLLRGTAESVRAVPAgTEVRCTLPGGRplTLYARRVFDSRPLPEL 160 Streptomyces coelicolor
Q82PA6  79 GRPIEGDitpLRYKMIRSDDFEALMAHDLAlSGGVQRVEATVEAVEGVPGgAEVYAYTAAGRplPVRARWVFDSRPLGSL 158 Streptomyces avermitilis
Q93CI8  76 FSRTLKG----GYATISSERMAEVMNERLC---AAIRTNARVAHVAPDHV------VLEGGE--RIDARAVVDGRG-PLA 139 Xanthobacter autotrop...
Q9KIX3  80 HAIRLST----AYLSMTSTRLRAEVEQRFP---ERILRDATAISATADHV------VLEGGR--TLRAPCVIDARG-GRP 143 Bradyrhizobium sp. OR...
Q9M424 152 HKTKYLG---RPYGRVSRKKLKLRLLNSCV-ENRVKFYKAKVWKVEHEEF--ESSIVCDDGK--KIRGSLVVDASG-FAS 222 potato
Q38933 153 GVKKDLS---RPYGRVNRKQLKSKMLQKCI-TNGVKFHQSKVTNVVHEEA--NSTVVCSDGV--KIQASVVLDATG-FSR 223 thale cress
Q8LJ81 259 RlleyevGGPRVCVQTAYGVEVEVENNPYDPSLMVFMDYRd---cFKDKFshpeqGNPTFLYAMPMSSTRIFFEETCLAS 335 Japanese rice
Q38932 250 KllqyevGGPRVCVQTAYGVEVEVENSPYDPDQMVFMDYRd---yTNEKVrsleaEYPTFLYAMPMTKSRLFFEETCLAS 326 thale cress
O65837 247 KflqyelGSPRVSVQTAYGVEVEVDNNPFDPSLMVFMDYRd---yLRHDAqsleaKYPTFLYAMPMSPTRVFFEETCLAS 323 tomato
Q9RI55 161 P------PARTCLLQHFRGWFVHTRTDRFDPAVADLMDFR-----VPQPA-----HGLAFGYVLPLAPDRALVEYTEFSR 224 Streptomyces coelicolor
Q82PA6 159 P------AARTTLLQHFHGWFVRSDLPVFDPGTVELMDFR-----TPQPP-----RGLSFGYVLPTGRRQALVEYTEFSP 222 Streptomyces avermitilis
Q93CI8 140 S------RHLDLGYQTFLGQELRMSRP-HGLTRPIIMDAR-----VEQL------GGYRFVYVLPLDDDTLLVEDTYYAD 201 Xanthobacter autotrop...
Q9KIX3 144 V------PGLALGFQKFLGLEVRLAAP-HGLDVPIVMDAT-----VAQS------DGYRFVYTLPLDPQRLLIEDTYYSD 205 Bradyrhizobium sp. OR...
Q9M424 223 Dfie-ydKPRNHGYQIAHGVLVEVDNHPFDLDKMVLMDWRdshlgNEPYLrvnnaKEPTFLYAMPFDRNLVFLEETSLVS 301 potato
Q38933 224 Clvq-ydKPYNPGYQVAYGIVAEVDGHPFDVDKMVFMDWRdkhldSYPELkernsKIPTFLYAMPFSSNRIFLEETSLVA 302 thale cress
Q8LJ81 336 KEAMPFDLLKKRLMSRLDA-MGVHIRKVYEEEWSYIPV--GGSLPNTDQK----NLAFGAAASMVHPATGYSVVRSLSEA 408 Japanese rice
Q38932 327 KDVMPFDLLKTKLMLRLDT-LGIRILKTYEEEWSYIPV--GGSLPNTEQK----NLAFGAAASMVHPATGYSVVRSLSEA 399 thale cress
O65837 324 KDAMPFDLLKKKLMLRLNT-LGVRIKEIYEEEWSYIPV--GGSLPNTEQK----TLAFGAAASMVHPATGYSVVRSLSEA 396 tomato
Q9RI55 225 AP-LTTEAYESALGHYCRDiLGLGELTVERTEQGVIPMtdARFPGRAGPA----VYRIGTAGGATRPATGYTFAAVQRHS 299 Streptomyces coelicolor
Q82PA6 223 AV-LPRSAYEAALRHYTRDiLHLPGLEIVSTETGVIPMtdAPFARQTAAS----VFRIGAAGGATRPSTGYTFAAVQRQT 297 Streptomyces avermitilis
Q93CI8 202 GPDLPADALRGRISAYAAA-QGWAVDYVVREEDGILPIalGGDINAFLAEtpsgVAPAGLRAGLFHPTTGYSLPDAMALA 280 Xanthobacter autotrop...
Q9KIX3 206 GGELPEQVLHQRIARYALA-KGWQIAEIIRAEQGVLPVilAGDPSGLVSKpd-sPPRVGLAALLVHPTTGYSLPDAVRVA 283 Bradyrhizobium sp. OR...
Q9M424 302 RPVLSYMEVKRRMVARLRH-LGIKVRSVIEEEKCVIPM--GGPLPRIPQN----VMAIGGNSGIVHPSTGYMVARSMALA 374 potato
Q38933 303 RPGLRMEDIQERMAARLKH-LGINVKRIEEDERCVIPM--GGPLPVLPQR----VVGIGGTAGMVHPSTGYMVARTLAAA 375 thale cress
Q8LJ81 409 PRYASVISDILRNRvypgeylpgtsqssSPSMLAWRTLWPQERKRQRSFF-LFGLALIIQLNNEGIQTFFETFFRLPKWM 487 Japanese rice
Q38932 400 PKYASVIAEILREEttkq-------insNISRQAWDTLWPPERKRQRAFF-LFGLALIVQFDTEGIRSFFRTFFRLPKWM 471 thale cress
O65837 397 PKCASVLANILRQHysknml--tsssipSISTQAWNTLWPQERKRQRSFF-LFGLALILQLDIEGIRSFFRAFFRVPKWM 473 tomato
Q9RI55 300 G----AIAAALR----------------DGHDRVPAPHGRRARAMDAVLLrALD-----TGRIDGPRFFTDLFRRVPAER 354 Streptomyces coelicolor
Q82PA6 298 R----AVAAALCR---------------GRRPLPPPAHSARSRAMDAVLLrALD-----SGRIGGAAFFARLFSRVPMER 353 Streptomyces avermitilis
Q93CI8 281 D----SVSALADLS--------------GPALSAAVRSHAAAAWNGRGFFrLLNRMLFRAADPERRYAILQRFYGLSEDL 342 Xanthobacter autotrop...
Q9KIX3 284 DLLTARLAQRGALS--------------SADARETIDGYGRTIWRRRGYYrFLNRMLFKAAEPSERHRILARFYGLDQAL 349 Bradyrhizobium sp. OR...
Q9M424 375 PVLAEAIVKGLGstrm--------irgsQLYHRVWNGLWPLDRRCIGECY-SFGMETLLKLDLKGTRRLFDAFFDLDPKY 445 potato
Q38933 376 PIVANAIVRYLGSPssns------lrgdQLSAEVWRDLWPIERRRQREFF-CFGMDILLKLDLDATRRFFDAFFDLQPHY 448 thale cress
Q8LJ81 488 WRGFLGSTLSSVDLILFAFY---MFTIAPNQMRM 518 Japanese rice
Q38932 472 WQGFLGSTLTSGDLVLFALY---MFVISPNNLRK 502 thale cress
O65837 474 WQGFLGSSLSSADLMLFAFY---MFIIAPNDMRK 504 tomato
Q9RI55 355 LLRFLDGTTSLREEWGIGLR---TPVRPMLRTAA 385 Streptomyces coelicolor
Q82PA6 354 LLRFLDGCTHLHEDLSIGVH---TPVLPMLRSAa 384 Streptomyces avermitilis
Q93CI8 343 IARFYADRLTLADKARILSG---RPPVSVFRALS 373 Xanthobacter autotrophicus Py2
Q9KIX3 350 IERFYAARIQPQDKLRVFMHmlmKPPIPISSALA 383 Bradyrhizobium sp. ORS 278
Q9M424 446 WQGFLSSRLSVKELAILSLC---LFGHGSNLTRL 476 potato
Q38933 449 WHGFLSSRLFLPELLVFGLS---LFSHASNTSRL 479 thale cress
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