5IRM


Conserved Protein Domain Family
NACHT

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pfam05729: NACHT 
NACHT domain
This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Statistics
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PSSM-Id: 310381
View PSSM: pfam05729
Aligned: 26 rows
Threshold Bit Score: 109.701
Threshold Setting Gi: 171677728
Created: 18-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IRM_A   83 DTVLVVGEAGSGKSTLLQQVHLLWATGQDFQe--fLFVFPFSCRQLQCVARPl----SVMTLLFEHCCWPDVGQQDvf-- 154  rabbit
Q9NPP4  163 SPCIIEGESGKGKSTLLQRIAMLWGSGKCKAltkfKFVFFLRLSRAQG---------GLFETLCDQLLDIPGTIRKqtf- 232  human
Q13075  464 SVMCVEGEAGSGKTVLLKKIAFLWASGCCPLlnrfQLVFYLSLSSTRPDE-------GLASIICDQLLEKEGSVTEmcv- 535  human
Q9R016  464 SVMCVEGETGSGKTTFLKRIAFLWASGCCPLlyrfQLVFYLSLSSITPDQ-------GLANIICAQLLGAGGCISEvcl- 535  house mouse
Q55138  133 RYLAIVGEAGSGKTIFLQHFAQGLWQRHQEGqa-hCLPIWLNPSRFKHR--------SIKDYLFGPWLQEAMALEE---- 199  Synechocystis sp. P...
O16302  458 LPIILQGENGCGKTSLMAKIATKIREWYDNSc--ePVVLLRFLGTSPDSSNIaplltSVCDQIASNYDESLKNSSPtels 535  Caenorhabditis elegans
Q99973 1162 RLSLVTGQSGQGKTAFLASLVSALQAPDGAKv--aSLVFFHFSGARPDQGLAltllrRLCTYLRGQLKEPGALPSTyr-- 1237 human
O08653 1175 RLSLVIGQAGQGKTAFLASLVSALKVPDQPNv--aPFVFFHFSAARPDQCLAfnllrRLCTHLHQKLGEPSALPSTyr-- 1250 Norway rat
Q9X8M7  254 DRVLLRGGAGSGKTTLVQWLAVAAAREGs------RVPFVLPVRRFAREGFP-----APDDFLHAVRHPLADRAPEgw-- 320  Streptomyces coelic...
Q9X8M9  267 DRVLLRGDAGSGKTTLVQWLAVTAARDGd------RVPYVLPLRTLTRAGALp----SPAAFLTAVGCPLTPPEgw---- 332  Streptomyces coelic...
5IRM_A  155 ---------qfLLDHPDRIL--------------LTFDGFDEFKFKFTDherhcsptdptsvqtlLFNLLQGNLLKNARK 211  rabbit
Q9NPP4  233 --------mamLLKLRQRVL--------------FLLDGYNEFKPQNCPe---------------IEALIKENHRFKNMV 275  human
Q13075  536 --------rniIQQLKNQVL--------------FLLDDYKEICSIPQV----------------IGKLIQKNHLSRTCL 577  human
Q9R016  536 --------sssIQQLQHQVL--------------FLLDDYSGLASLPQA----------------LHTLITKNYLSRTCL 577  house mouse
Q55138  200 -------------EIPPATWrdslllglqtgqfwLVLDGIDYTFTDPSQmsgaq------gsltwLKDSLAE--VPTTPV 258  Synechocystis sp. P...
O16302  536 klfqhfkkitnLATREKPLV--------------IIFDSLDLLSRIDGAhe-------------lL--WFPPSLPPFVKL 586  Caenorhabditis elegans
Q99973 1238 ---------slVWELQQRLLpksaeslhpgqtqvLIIDGADRLVDQNGQl---------------ISDWIPKKLPRCVHL 1293 human
O08653 1251 ---------glVWELQQKLLlksaqwlqpgqtlvLIIDGADKLVDHNGQl---------------ISDWIPKSLPRRVHL 1306 Norway rat
Q9X8M7  321 ---------vvRTLLAGRAL--------------LLVDGIDEAPEktrge-----------lrdrLRRLLRV--FSGNGC 364  Streptomyces coelic...
Q9X8M9  333 ---------aeRVLNAGRGL--------------VLVDGLDEIPAadrnr-----------trdwLLGLVRA--FPGNRW 376  Streptomyces coelic...
5IRM_A  212 VLTSRPDAVSA---FLRKYVRT----EFNLKGFSEEGIELYL-RKCHREP 253  rabbit
Q9NPP4  276 IVTTTTECLRH---IRQFGALT-----AEVGDMTEDSAQALI-REVLIKE 316  human
Q13075  578 LIAVRTNRARD---IRRYLETI-----LEIKAFPFYNTVCIL-RKLFSHN 618  human
Q9R016  578 LIAVHTNRVRD---IRLYLGTS-----LEIQEFPFYNTVSVL-RKFFSHD 618  house mouse
Q55138  259 LLSCRPDTRRN---DPRGLAGFt---RYQIEPLVYPDNVEIAiEDYFSAD 302  Synechocystis sp. PCC 6803
O16302  587 FASLTPGGSLIyskMQRLIEDKr--qYLMVPSLGKDLGFQVV-REWLSDK 633  Caenorhabditis elegans
Q99973 1294 VLSVSSDAG-----LGETLEQSqgahVLALGPLEASARARLV-REELALY 1337 human
O08653 1307 VLSVSSDSG-----LGETLQQSqsayVVALGSLVPSSRAQLV-REELALY 1350 Norway rat
Q9X8M7  365 LVTSRPSAVSEgwlSGGGLAEEdf-vELSLAPMSRDRVTRFI-RDWHSAA 412  Streptomyces coelicolor
Q9X8M9  377 LLTSRPTAVRPdwlAAEGFREL------ALTPMRQDDVATFV-RRWHAAA 419  Streptomyces coelicolor
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