5IRM,6B5B


Conserved Protein Domain Family
NACHT

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pfam05729: NACHT 
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NACHT domain
This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Statistics
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Aligned: 27 rows
Threshold Bit Score: 110.088
Threshold Setting Gi: 170936932
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5IRM_A     83 DTVLVVGEAGSGKSTLLQQVHLLWATGQDFQe--fLFVFPFSCRQLQCVARPl----SVMTLLFEHCCWPDVGQQDvf-- 154  rabbit
Q9R016    464 SVMCVEGETGSGKTTFLKRIAFLWASGCCPLlyrfQLVFYLSLSSITPDQ-------GLANIICAQLLGAGGCISEvcl- 535  house mouse
Q13075    464 SVMCVEGEAGSGKTVLLKKIAFLWASGCCPLlnrfQLVFYLSLSSTRPDE-------GLASIICDQLLEKEGSVTEmcv- 535  human
Q55138    133 RYLAIVGEAGSGKTIFLQHFAQGLWQRHQEGqa-hCLPIWLNPSRFKHR--------SIKDYLFGPWLQEAMALEE---- 199  Synechocystis sp....
O16302    458 LPIILQGENGCGKTSLMAKIATKIREWYDNSc--ePVVLLRFLGTSPDSSNIaplltSVCDQIASNYDESLKNSSPtels 535  Caenorhabditis el...
Q99973   1162 RLSLVTGQSGQGKTAFLASLVSALQAPDGAKv--aSLVFFHFSGARPDQGLAltllrRLCTYLRGQLKEPGALPSTyr-- 1237 human
O08653   1175 RLSLVIGQAGQGKTAFLASLVSALKVPDQPNv--aPFVFFHFSAARPDQCLAfnllrRLCTHLHQKLGEPSALPSTyr-- 1250 Norway rat
Q9X8M7    254 DRVLLRGGAGSGKTTLVQWLAVAAAREGs------RVPFVLPVRRFAREGFP-----APDDFLHAVRHPLADRAPEgw-- 320  Streptomyces coel...
Q9X8M9    267 DRVLLRGDAGSGKTTLVQWLAVTAARDGd------RVPYVLPLRTLTRAGALp----SPAAFLTAVGCPLTPPEgw---- 332  Streptomyces coel...
CAP61591  294 RLLWINGDPGKGKTMLLCGIIDELKKSTPPG----LLSFFFCQATDSRINNAtavlrGLIYLLVSQQPALISHVRRpydh 369  Podospora anserin...
5IRM_A    155 ------------qfLLDHPDRIL--------------LTFDGFDEFKFKFTDherhcsptdptsvqtlLFNLLQGNLLKN 208  rabbit
Q9R016    536 -----------sssIQQLQHQVL--------------FLLDDYSGLASLPQA----------------LHTLITKNYLSR 574  house mouse
Q13075    536 -----------rniIQQLKNQVL--------------FLLDDYKEICSIPQV----------------IGKLIQKNHLSR 574  human
Q55138    200 ----------------EIPPATWrdslllglqtgqfwLVLDGIDYTFTDPSQmsgaq------gsltwLKDSLAE--VPT 255  Synechocystis sp....
O16302    536 klfq---hfkkitnLATREKPLV--------------IIFDSLDLLSRIDGAhe-------------lL--WFPPSLPPF 583  Caenorhabditis el...
Q99973   1238 ------------slVWELQQRLLpksaeslhpgqtqvLIIDGADRLVDQNGQl---------------ISDWIPKKLPRC 1290 human
O08653   1251 ------------glVWELQQKLLlksaqwlqpgqtlvLIIDGADKLVDHNGQl---------------ISDWIPKSLPRR 1303 Norway rat
Q9X8M7    321 ------------vvRTLLAGRAL--------------LLVDGIDEAPEktrge-----------lrdrLRRLLRV--FSG 361  Streptomyces coel...
Q9X8M9    333 ------------aeRVLNAGRGL--------------VLVDGLDEIPAadrnr-----------trdwLLGLVRA--FPG 373  Streptomyces coel...
CAP61591  370 agkkmfegpnvwivLCEIFTSILqdpgl-----rmtyLIIDALDECVTDLPQ----------------LLELITRTSCTS 428  Podospora anserin...
5IRM_A    209 ARKVLTSRPDAVSA---FLRKYVRT---------------EFNLKGFSEEGIELYL-RKCHREP 253  rabbit
Q9R016    575 TCLLIAVHTNRVRD---IRLYLGTS----------------LEIQEFPFYNTVSVL-RKFFSHD 618  house mouse
Q13075    575 TCLLIAVRTNRARD---IRRYLETI----------------LEIKAFPFYNTVCIL-RKLFSHN 618  human
Q55138    256 TPVLLSCRPDTRRN---DPRGLAGFt--------------RYQIEPLVYPDNVEIAiEDYFSAD 302  Synechocystis sp. PCC 6803
O16302    584 VKLFASLTPGGSLIyskMQRLIEDKr-------------qYLMVPSLGKDLGFQVV-REWLSDK 633  Caenorhabditis elegans
Q99973   1291 VHLVLSVSSDAG-----LGETLEQSqg-----------ahVLALGPLEASARARLV-REELALY 1337 human
O08653   1304 VHLVLSVSSDSG-----LGETLQQSqs-----------ayVVALGSLVPSSRAQLV-REELALY 1350 Norway rat
Q9X8M7    362 NGCLVTSRPSAVSEgwlSGGGLAEEdf------------vELSLAPMSRDRVTRFI-RDWHSAA 412  Streptomyces coelicolor
Q9X8M9    374 NRWLLTSRPTAVRPdwlAAEGFREL-----------------ALTPMRQDDVATFV-RRWHAAA 419  Streptomyces coelicolor
CAP61591  429 SPIKWIVSSRNWPD---IEEQLETAtqkarlslelnaesiSTAVNAFIQNRIDQLA-SKTKHDA 488  Podospora anserina S mat+
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