5YUD


Conserved Protein Domain Family
NACHT

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pfam05729: NACHT 
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NACHT domain
This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Statistics
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PSSM-Id: 399032
View PSSM: pfam05729
Aligned: 25 rows
Threshold Bit Score: 108.929
Threshold Setting Gi: 170936932
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5YUD_A    464 SVMCVEGETGSGKTTFLKRIAFLWASGCCPLlyrfQLVFYLSLSSITPDQ-------GLANIICAQLLGAGGCISEvcl- 535  house mouse
Q9NPP4    163 SPCIIEGESGKGKSTLLQRIAMLWGSGKCKAltkfKFVFFLRLSRAQG---------GLFETLCDQLLDIPGTIRKqtf- 232  human
CAP61591  294 RLLWINGDPGKGKTMLLCGIIDELKKSTPPG----LLSFFFCQATDSRINnatavlrGLIYLLVSQQPALISHVRRpydh 369  Podospora anserin...
Q13075    464 SVMCVEGEAGSGKTVLLKKIAFLWASGCCPLlnrfQLVFYLSLSSTRPDE-------GLASIICDQLLEKEGSVTEmcv- 535  human
Q55138    133 RYLAIVGEAGSGKTIFLQHFAQGLWQRHQEGqa-hCLPIWLNPSRFKHR--------SIKDYLFGPWLQEAMALEE---- 199  Synechocystis sp....
O16302    458 LPIILQGENGCGKTSLMAKIATKIREWYDNSc--ePVVLLRFLGTSPDSSniaplltSVCDQIASNYDESLKNSSPtels 535  Caenorhabditis el...
Q99973   1162 RLSLVTGQSGQGKTAFLASLVSALQAPDGAKv--aSLVFFHFSGARPDQGlaltllrRLCTYLRGQLKEPGALPSTyr-- 1237 human
O08653   1175 RLSLVIGQAGQGKTAFLASLVSALKVPDQPNv--aPFVFFHFSAARPDQClafnllrRLCTHLHQKLGEPSALPSTyr-- 1250 Norway rat
Q9X8M7    254 DRVLLRGGAGSGKTTLVQWLAVAAAREGs------RVPFVLPVRRFAREGf-----pAPDDFLHAVRHPLADRAPEgw-- 320  Streptomyces coel...
Q9X8M9    267 DRVLLRGDAGSGKTTLVQWLAVTAARDGd------RVPYVLPLRTLTRAGal----pSPAAFLTAVGCPLTPPEgw---- 332  Streptomyces coel...
5YUD_A    536 -----------sssIQQLQHQVL--------------FLLDDYSGLASLPQA----------LHTLITKNYLSRTCLLIA 580  house mouse
Q9NPP4    233 -----------mamLLKLRQRVL--------------FLLDGYNEFKPQNCPe---------IEALIKENHRFKNMVIVT 278  human
CAP61591  370 agkkmfegpnvwivLCEIFTSILqdpgl-----rmtyLIIDALDECVTDLPQ----------LLELITRTSCTSSPIKWI 434  Podospora anserin...
Q13075    536 -----------rniIQQLKNQVL--------------FLLDDYKEICSIPQV----------IGKLIQKNHLSRTCLLIA 580  human
Q55138    200 ----------------EIPPATWrdslllglqtgqfwLVLDGIDYTFTDPSQmsgaqgsltwLKDSLAE--VPTTPVLLS 261  Synechocystis sp....
O16302    536 klfq---hfkkitnLATREKPLV--------------IIFDSLDLLSRIDGAhe-------lL--WFPPSLPPFVKLFAS 589  Caenorhabditis el...
Q99973   1238 ------------slVWELQQRLLpksaeslhpgqtqvLIIDGADRLVDQNGQl---------ISDWIPKKLPRCVHLVLS 1296 human
O08653   1251 ------------glVWELQQKLLlksaqwlqpgqtlvLIIDGADKLVDHNGQl---------ISDWIPKSLPRRVHLVLS 1309 Norway rat
Q9X8M7    321 ------------vvRTLLAGRAL--------------LLVDGIDEAPEktrge-----lrdrLRRLLRV--FSGNGCLVT 367  Streptomyces coel...
Q9X8M9    333 ------------aeRVLNAGRGL--------------VLVDGLDEIPAadrnr-----trdwLLGLVRA--FPGNRWLLT 379  Streptomyces coel...
5YUD_A    581 VHTNRVRD---IRLYLGTS----------------LEIQEFPFYNTVSVL-RKFFSHD 618  house mouse
Q9NPP4    279 TTTECLRH---IRQFGALT----------------AEVGDMTEDSAQALI-REVLIKE 316  human
CAP61591  435 VSSRNWPD---IEEQLETAtqkarlslelnaesisTAVNAFIQNRIDQLA-SKTKHDA 488  Podospora anserina S mat+
Q13075    581 VRTNRARD---IRRYLETI----------------LEIKAFPFYNTVCIL-RKLFSHN 618  human
Q55138    262 CRPDTRRN---DPRGLAGFt--------------rYQIEPLVYPDNVEIAiEDYFSAD 302  Synechocystis sp. PCC 6803
O16302    590 LTPGGSLIyskMQRLIEDKrq-------------yLMVPSLGKDLGFQVV-REWLSDK 633  Caenorhabditis elegans
Q99973   1297 VSSDAG-----LGETLEQSqga-----------hvLALGPLEASARARLV-REELALY 1337 human
O08653   1310 VSSDSG-----LGETLQQSqsa-----------yvVALGSLVPSSRAQLV-REELALY 1350 Norway rat
Q9X8M7    368 SRPSAVSEgwlSGGGLAEEdf------------veLSLAPMSRDRVTRFI-RDWHSAA 412  Streptomyces coelicolor
Q9X8M9    380 SRPTAVRPdwlAAEGFREL-----------------ALTPMRQDDVATFV-RRWHAAA 419  Streptomyces coelicolor
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