1FPZ


Conserved Protein Domain Family
CDKN3

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pfam05706: CDKN3 
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Cyclin-dependent kinase inhibitor 3 (CDKN3)
This family consists of cyclin-dependent kinase inhibitor 3 or kinase associated phosphatase proteins from several mammalian species. The cyclin-dependent kinase (Cdk)-associated protein phosphatase (KAP) is a human dual specificity protein phosphatase that dephosphorylates Cdk2 on threonine 160 in a cyclin-dependent manner.
Statistics
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PSSM-Id: 203311
View PSSM: pfam05706
Aligned: 3 rows
Threshold Bit Score: 313.497
Threshold Setting Gi: 81895574
Created: 23-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1FPZ_A   1 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCT 80  human
Q810P3   1 MKPPISIQASEFDSSDEEPVDEEQTPIQISWLPLSRVNCSQFLGLCALPGCKFKDVRRNIQKDTEELKSYGIQDVFVFCT 80  house mouse
Q16667   1 MKPPSSIQTSEFDSSDEEPIEDEQTPIHISWLSLSRVNCSQFLGLCALPGCKFKDVRRNVQKDTEELKSCGIQDIFVFCT 80  human
1FPZ_A  81 RGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHSYGGLGRSCLvAACLLLYLSD 160 human
Q810P3  81 RGELSKYRVPNLLDLYQQYGIVTHHHPIPDGGTPDIGSCWEIMEELATCLKNNRKTLIHCYGGLGRSCL-AACLLLYLSD 159 house mouse
Q16667  81 RGELSKYRVPNLLDLYQQCGIITHHHPIADGGTPDIASCCEIMEELTTCLKNYRKTLIHCYGGLGRSCLvAACLLLYLSD 160 human
1FPZ_A 161 TISPEQAI 168 human
Q810P3 160 SISPQQAI 167 house mouse
Q16667 161 TISPEQAI 168 human
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