2JRF


Conserved Protein Domain Family
p25-alpha

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pfam05517: p25-alpha 
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p25-alpha
This family encodes a 25 kDa protein that is phosphorylated by a Ser/Thr-Pro kinase. It has been described as a brain specific protein, but it is found in Tetrahymena thermophila.
Statistics
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PSSM-Id: 368481
View PSSM: pfam05517
Aligned: 72 rows
Threshold Bit Score: 98.4923
Threshold Setting Gi: 121968940
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JRF_A        11 EESFRKFAIHGdpKASGQEMNGKNWAKLCKDCKVADgKSVTGTDVDIVFSKVKGKSA-RVINYEEFKKALEELATKrfkG 89  human
A0CF04         6 QQVFLQFTAN------KPEMDGKTFAKVSKDCHLLD-KKLTSTDVDLIFAKIKPTPAaRSITYAQFEKGLQMMAEK---K 75  Paramecium tetr...
EGR31686       7 ETCFKAFTSG------KAEMDGKTFAKVTKDCHLQD-KKLTSTDVDLIFAKVKTSSAvRTITFKQFESGLSQIAAK---K 76  Ichthyophthiriu...
Q244Y3         6 EGVFKKFTGG------KIEMDGKTFAKFAKDTGLLD-KKLTATDVDLIFAKVKGSSAiRCINIRQFEEGINQFAAK---K 75  Tetrahymena the...
Q22LY3         4 SAAFKKFTNQ------RSTMDSKTFVNTLADSGIFN-FKITTHQSEQIFEKVKNSPNlRGINYQQFETCLSLVASQ---T 73  Tetrahymena the...
Q244Y1         6 EGVFKKFTAN------KADMDGKTFAKFAKDCGLLD-KKLTATDIDLIFAKVKTSSAvRTITFAQFEKGLDQMATK---K 75  Tetrahymena the...
CDI84153       4 KDAFNAYTKG------ADEMDGRTFTKILRDCKILD-SKVTGVDADLIFTKVKAKGA-KKITFAEFEEALRLVAAK---K 72  Eimeria acervulina
XP_001613902   2 ENAFYIYTKN------EADMDSRTFVKILKDAKLLS-KKLTAVDADLTFAKVKAKGA-KRINYDQFVEAVKHLVDK---H 70  malaria parasit...
Q8I557         2 ENAFYVYTKN------LPDMDSRTFVKILKDAKLLN-KKFTTVDADLIFAKVKSKGA-KRINYDQFLEAVKCIVEK---N 70  Plasmodium falc...
CBN76132       5 EQIFLDFTSFGagQSGSSEMDSAKFVKLAKDCKLVG-KNLSTTDLDLIFTKVKDKTA-KKINFDTFVEAVELISEK---L 79  Ectocarpus sili...
2JRF_A        90 KSKEEAFdaICQLVAGK--EPANV-GvtkaKTGGAVDRLTDTSRYTGSHKE----RFD-ESGKGKGIAGRQDILdDSGYV 161 human
A0CF04        76 GVGVQDV--HNQILNAG--GPHFQ-G----TKADAVKFHDDKNLYTGVHANggpsTIDkNHGGLNTI---CDR--SQADV 141 Paramecium tetr...
EGR31686      77 GVSVEDV--IKNITSAG--GPQFQ-G----TKADYVKFHDDKSQYTGVYANggptNVD--KDKISDISQTCNR--QAADV 143 Ichthyophthiriu...
Q244Y3        76 GISAQDL--REKVTASN--GPSYS-G----TKADAVRFHDDKSLYTGVYANggpsTIDiGSGKISDISQLCDR--TSADV 144 Tetrahymena the...
Q22LY3        74 GCTRQQI--EGLVLEYS---KKFT-T----KQADPSRFFYDKSTYTGVHTKggpsTLD--NNGYSQLSQLCDR--SSANV 139 Tetrahymena the...
Q244Y1        76 GISLDAL--KEKVTSAG--GPTFT-G----TKADAVKFHDDKSLYTGVYANggpsTVDiGNGKISDISQLCDR--TGADV 144 Tetrahymena the...
CDI84153      73 GVEVEAL--HAKLAEEGtqGPILT-G----TKADNVRFHDDKSTYTGVHKMggptTVDdGRVQFNDLSKICDR--SEYDV 143 Eimeria acervulina
XP_001613902  71 KLDYDQF--VEKLCNEAssGPILY-G----TKAANVRFHDDKSTYTGVHKMggptTVDkNKTHFSDISEITDR--SECNI 141 malaria parasit...
Q8I557        71 KLNYDKF--VETLCQEAskGPILY-G----TKTENVRFFDDKSTFTGVHKQggpsIIDkNKTQFSDLSEITDR--SEYDI 141 Plasmodium falc...
CBN76132      80 GKSKDDV--ILLIVSAK--GPTTGaA----TVADNVRFHDDKSTFTGVHNNggptNID---GHNVDMANQLDRS-EGADV 147 Ectocarpus sili...
2JRF_A       162 SAYKN 166 human
A0CF04       142 RGSQK 146 Paramecium tetraurelia
EGR31686     144 RGTLK 148 Ichthyophthirius multifiliis
Q244Y3       145 RGVKH 149 Tetrahymena thermophila SB210
Q22LY3       140 RGIKN 144 Tetrahymena thermophila SB210
Q244Y1       145 RGVKK 149 Tetrahymena thermophila SB210
CDI84153     144 RGVKK 148 Eimeria acervulina
XP_001613902 142 RGVNL 146 malaria parasite P. vivax
Q8I557       142 RGVKM 146 Plasmodium falciparum 3D7
CBN76132     148 RGVKE 152 Ectocarpus siliculosus
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