4H6U


Conserved Protein Domain Family
Acetyltransf_16

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pfam05301: Acetyltransf_16 
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GNAT acetyltransferase, Mec-17
Mec-17 is the protein product of one of the 18 genes required for the development and function of the touch receptor neuron for gentle touch. Mec-17 is specifically required for maintaining the differentiation of the touch receptor. The family shares all the residue-motifs characteristic of Gcn5-related acetyl-transferases, though the exact unction is still unknown.
Statistics
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PSSM-Id: 336093
View PSSM: pfam05301
Aligned: 37 rows
Threshold Bit Score: 219.742
Threshold Setting Gi: 168025715
Created: 21-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4H6U_A        12 NALFPERISVLD-S-------N-------LSAGRKa-----------HGr--pDPlpQVTTVIDELGKASSKAQQLPAPI 63
gi 74958956    8 RPILGPQLVRLD-P-------Mrvk-------------------------qlqDP--IVYEAIDNLAKLSAHCLQLRTPL 52
gi 74966631    8 STIFTDNIQRLT-R-------TdllkygpKR----------------------YW--AVAQSIDCLGEMSSKFHGWKRVI 55
gi 255083454   8 agLTPGGVSVWT-R-------D-------AI--VRl-----------PPd--eYR--AISALIDEAGARSARAQGLPAPI 55
gi 302797915  12 sgpqGARVTIWD-G-------Q-------KL--GRl-----------NPa--eKE--DMRRVIDDMGRLSAQAQKLKVPI 59
gi 313228861   8 SDVLPQNITAFR-QeeisrlnY-------SLPRRYhsaydsrrgaavVHs--kGE--KIQLIIDRLGKKSAEAQSLGSSI 75
gi 541043213 398 eyfedaPIQRLDlN-------T-------LKRLNPr----------------kCW--PVQRAIDGMGALSAEAQGLKRAL 445
gi 168025715  13 tftevPKITAWN-S-------Y-------QL-MNLm-----------RGk--dGE--EMQIIINYMGELSAIAQGLRGPI 61
gi 541048958   8 TPLLGPSLVRLD-A-------Mavk-------------------------qlqDA--RLYSAIDELALLSAKAMQLRQPL 52
gi 328721130   9 SNSHVGQVLKIN-N-------T-------LTAEGY------------ENnhelRN--NLRLIIDEIGKSSAIAQHLEFPI 59
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4H6U_A        64 TSAAKL-QA--NR--HHLYLL--KDG-EQn--GgRGVIVGFLKVGYKKLFLLDQ-RGAHLETE-PLCVLAFY------VT 125
gi 74958956   53 TTCEKL-IN--SD--STLYLSw-KYD-EEe--K-VSRLMGFAKVGRKKLFLYDS-QMQTYEGE-ILCLLDFY------VH 114
gi 74966631   56 TMYDKI-VDhdEE--QTTYIMw-EKV-NGs----KSILKGLLRVGYKTLYLTDN-E-QNQYMEkAMCILDFF------VV 118
gi 255083454  56 TSTDRL-L---ED--QRLYLAc-SDA-TRprgG-PSVLVGILKVGPKRLFVAKP-SGGMEEME-PCCVLDFY------VH 118
gi 302797915  60 TDYERI-RL--GS--QALYLLt-SSG-PSk--D-VILVKGLLKVGQKNLFIRKE-CGALVEIN-PLCVLDFY------VH 121
gi 313228861  76 TSFLQMtVG--NE--QSIYIL--RES-E--------LVLGFIKVGFKPLFIMDQ-NGNQSETR-PLCVLDFF------VM 132
gi 541043213 446 TSYDKL-VD--SDdgQVLYLMwkKDP-NRe--N-TSIVIGLLKIGYKCLYLVDA-TMKTFKTT-PLCILDFY------VH 510
gi 168025715  62 TSVDRL-LQ--SF--QKIYLL--TSSvPGn-sG-HILAQGILKVGQKHLFIRRTpNAPLVEIS-PLCVLDFYagtgayVI 131
gi 541048958  53 TTCEKL-VS--AD--NVLYLLw-EKD-EQt--S-MSRLLGMLKVGRKQLFLYDR-QMKTYEGE-LMALLDFY------VH 114
gi 328721130  60 TSAQKL-LN--SD--HVIYMM--TEQ-NTp--A-NFAVIGFLKMGWKKLFIYNK-QDTCSETL-VYCMLDFY------IY 120
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
4H6U_A       126 ETLQRHGYGSELFDFMLKHKQVEPAQMAY------DRPSPKFLSFLEKRYDLRNSVPQVNNFVVFAGFF 188
gi 74958956  115 FSCQRQGVGQQILDYMFSQEHTEPYQLAL------DNPSVTLLGFMSQKYGLIKPVWQNTNFVVFEELF 177
gi 74966631  119 PTEQRSGNGFKMFDEMLKAENVTVDQCAF------DKPSAALQQFLEKYYDRKDLVWQSNKYALCSNFF 181
gi 255083454 119 ESSQRGGWGSLLFDAFLQREDRHPARLAY------DRPSPKLVAFMAKHHNLRAFAKQNNNFVVFDEYW 181
gi 302797915 122 VSCQRIGLGRQIFDAMLVHTKKLAYQIGY------DRPSQKLLSFLAKHYNLKRFYPQANQFVIYNAYF 184
gi 313228861 133 EAYQRRGCGRRLFEFMLQDLSLHPAQLAI------DRPSTKFKSFLRKHYNLVGSVPQINNFVIFDGFF 195
gi 541043213 511 DTLQRMGNGHSLFECMLQHEGSPVERIAI------DKPSDSLLQFMNKYYALTDPLWQSTNYVVYAPFF 573
gi 168025715 132 QVHARAGEEEAMSAWVRLSSFPSPVPVPVeitsnyDKPSNKLLSFMSKYYNLRSYNDQANQFVVYNDYF 200
gi 541048958 115 FSLQRQGYGKKLFDFMLQCERVSAHEVAL------DNPTVTLLAFMAKHYGLTDAVWQNTNFVVFPQLF 177
gi 328721130 121 ESKQRQGYGKRLIEYMLQDMKLHARHLVM------DKPTTNLLQFMLKNFQLSKLVNQGNNFAIYEDFF 183
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