5TEY,5TEY


Conserved Protein Domain Family
MT-A70

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pfam05063: MT-A70 
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MT-A70
MT-A70 is the S-adenosylmethionine-binding subunit of human mRNA:m6A methyl-transferase (MTase), an enzyme that sequence-specifically methylates adenines in pre-mRNAs.
Statistics
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PSSM-Id: 309971
View PSSM: pfam05063
Aligned: 11 rows
Threshold Bit Score: 200.357
Threshold Setting Gi: 74962031
Created: 24-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5TEY_B 186 FDVILLEPPLEEYYRETGIt-----ANEKCWTWDDIMKLEIDEIAAP-RSFIFLWCGSGEGLDL--GRVCLRKWGYRRCE 257 human
Q09800 234 PKCIIIDPPWPNKSVARSS------VYKVNRNLGYLKALPIQESLSK-TGVVAVWCTNKEKYVNfvKKVLFKKWNLTLVS 306 Schizosaccharomyces p...
Q09956 185 FDLIIADPPWFSKSVKRK--------RTYQMDEEVLDCLDIPVILTH-DALIAFWITNRIGIEEe-MIERFDKWGMEVVA 254 Caenorhabditis elegans
Q9VER8 155 YDLIVLDPPWRNKYIRRLKrak-peLGYSMLSNEQLSHIPLSKLTHP-RSLVAIWCTNSTLHQLalEQQLLPSWNLRLLH 232 fruit fly
Q9KIW1  10 YQCIIIDPPWFYRLRSKDKthr-nrIPYQPMRTPEILALPIPDLCDAgGCVLWLWFTNNHMIEA---AQCLQRWGFDLKT 85  Nostoc sp. PCC 7120
Q9HCE5 186 FDVILLEPPLEEYY--RETgi---tANEKCWTWDDIMKLEIDEIAAP-RSFIFLWCGSGEGLDL--GRVCLRKWGYRRCE 257 human
P41833 342 FSVVIADPAWNIHMn----------LPYGTCNDIELLGLPLHELQDEg--IIFLWVTGRAIELG---KESLNNWGYNVIN 406 Saccharomyces cerevis...
Q86U44 389 FAVVMADPPWDIHMe----------LPYGTLTDDEMRRLNIPVLQDDg--FLFLWVTGRAMELG---RECLNLWGYERVD 453 human
O82486 476 FGVVMADPPWDIHMe----------LPYGTMADDEMRTLNVPSLQTDg--LIFLWVTGRAMELG---RECLELWGYKRVE 540 thale cress
Q9VLP7 158 FDVILIEPPLEEYARAAPSvatvggAPRVFWNWDDILNLDVGEIAAH-RSFVFLWCGSSEGLDM--GRNCLKKWGFRRCE 234 fruit fly
5TEY_A 407 FAVVMADPPWDIHMe----------LPYGTLTDDEMRRLNIPVLQDD-G-FLFLWVTGRAMELG---RECLNLWGYERVD 471 human
5TEY_B 258 DICWIKTNkNNPgKTK--TLDPKavFQRTKEHCLMGIKGTVKRSTDGDFIha-----nvDIDLIITeePEIGNIEKPVEI 330 human
Q09800 307 TWTWLKITaFGE-PLF--DVYSN--MRKPWEQLLIGVTSEYTSVYSDKIP---------PTFTIIG--IPDYHSRKPSLK 370 Schizosaccharomyces p...
Q09956 255 TWKLLKITtQGD-PVYdfD---NqkHKVPFESLMLAKKKDSMRKFe------------lPENFVFAsvPMSVHSHKPP-L 317 Caenorhabditis elegans
Q9VER8 233 KLRWYKLStDHE-LIAp--PQSDltQKQPYEMLYVACRSDASENYGKd----------iQQTELIFsvPSIVHSHKPPLL 299 fruit fly
Q9KIW1  86 ILTWGKVTkDGT-KTH---LGVGhwLRNSTEHCALAVRGNVKAFAGQTSTtggtptltnQSTILHS--PRREHSRKPPEF 159 Nostoc sp. PCC 7120
Q9HCE5 258 DICWIKTN-KNN-PGKtkTLDPKavFQRTKEHCLMGIKGTVKRSTDGDFIha-----nvDIDLIITeePEIGNIEKPVEI 330 human
P41833 407 EVSWIKTNqLGR-TIV--TGRTGhwLNHSKEHLLVGLKGNPK------WInk-----hiDVDLIVS--MTRETSRKPDEL 470 Saccharomyces cerevis...
Q86U44 454 EIIWVKTNqLQR-IIR--TGRTGhwLNHGKEHCLVGVKGNPQ------GFnq-----glDCDVIVA--EVRSTSHKPDEI 517 human
O82486 541 EIIWVKTNqLQR-IIR--TGRTGhwLNHSKEHCLVGIKGNP-------EVnr-----niDTDVIVA--EVRETSRKPDEM 603 thale cress
Q9VLP7 235 DICWIRTN-INK-PGHskQLEPKavFQRTKEHCLMGIKGTVRRSTDGDFIha-----nvDIDLIISeeEEFGSFEKPIEI 307 fruit fly
5TEY_A 472 EIIWVKTNqLQR-IIR--TGRTGhwLNHGKEHCLVGVKGNPQ------GFnq-----glDCDVIVA--EVRSTSHKPDEI 535 human
5TEY_B 331 FHIIEHFCl----GRR-RLHLFGRDstIRPGWLTVGPT 363 human
Q09800 371 PFISRWFNcsaneSLP-VLEIFGRS--LTPNWITWGRE 405 Schizosaccharomyces pombe 972h-
Q09956 318 LDLLRHFGi---eFTE-PLELFARS--LLPSTHSVGYE 349 Caenorhabditis elegans
Q9VER8 300 SWLREHLLldkdqLEPnCLELFARY--LHPHFTSIGLE 335 fruit fly
Q9KIW1 160 FELVEKLCp----DMT-KLEIFARE--SRDGWDCWGDQ 190 Nostoc sp. PCC 7120
Q9HCE5 331 FHIIEHFCl----GRR-RLHLFGRDstIRPGWLTVGPT 363 human
P41833 471 YGIAERLAg---tHAR-KLEIFGRDhnTRPGWFTIGNQ 504 Saccharomyces cerevisiae S288c
Q86U44 518 YGMIERLSp----GTR-KIELFGRPhnVQPNWITLGNQ 550 human
O82486 604 YAMLERIMp----RAR-KLELFARMhnAHAGWLSLGNQ 636 thale cress
Q9VLP7 308 FHIIEHFCl----GRR-RLHLFGRDssIRPGWLTVGPE 340 fruit fly
5TEY_A 536 YGMIERLSp----GTR-KIELFGRPhnVQPNWITLGNQ 568 human
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