Conserved Protein Domain Family
Yip1

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pfam04893: Yip1 
Yip1 domain
The Yip1 integral membrane domain contains four transmembrane alpha helices. The domain is characterized by the motifs DLYGP and GY. The Yip1 protein is a golgi protein involved in vesicular transport that interacts with GTPases.
Statistics
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PSSM-Id: 309843
View PSSM: pfam04893
Aligned: 206 rows
Threshold Bit Score: 34.3119
Threshold Setting Gi: 122512324
Created: 17-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121724216   15 VITAPDELFYLKSQYKNyegv-------------ltsiFFTAFLGLILGIYLKd---------------------iIVTI 60
gi 82179633    79 FDIDTYQVLDRIRGSIIpipgrnfvrn-hlknspdlygPFWICATLVITVTIMgnlgtytilhdqadyqyspefhkLSVA 157
gi 82105831    81 FDIETHHVKERIIGSMTpwpgknfirv-ylrrnpdlygPFWICTTLVFAIAISgnisnfltnlgkpnyrytpefrkVTIA 159
gi 75042045    86 FDVDTYQVFDRIKGSLLpipgknfvrl-yirsnpdlygPFWICATLVFAIAISgnlsnflihlgektyryvpefrkVSIA 164
gi 81883841    83 FDVDTSQVLDRIKGSLLphpghnfvrh-hlrnrpdlygPFWICATLAFVLAVTgnltlvlaqrrdpsihyspqfhkVTIA 161
gi 82182100    82 FNVDTVQVLDRIKGSVMplpgrnfikh-hirsnpdlygPFWICVTLVFSLAISgnlstflsemgnpeyhyrpqfhrVSIA 160
gi 74633374    91 FDVDAKEVGDKIVQAVNplsgggqsstyfldqpadlygPFWIASTLIFALFFAntlvgliknss--gekfsyefglITAN 168
gi 74625942    56 FNVETKDVVQRCIHTLIptvnffdvv----ddrpdlygPFWITTTVIQALFFSnsiteyaryat-ghgtsgysikkLISA 130
gi 74616668    96 FDVDTSSVLQRCWAALYpranfldvl----egnpdlygPFWIATTVVLILFLGgtisdylaqtg--keafaydfrlLSGA 169
82_pfamImport   1 FQIDLTQFKKRLSAVLTfrndhnses---nedntdlygAVWITATVVMINFTMsrglnfiisd----viegvktgeDIDR 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121724216   61 GIivcAIILV-------LLNNIIHSIITSIiariLG-------GTGNLLNLFNLISYT---SVLDIFFIFVLSIFSFKP- 122
gi 82179633   158 GVaiySYAW--------AVPLGLWGFLQWRkgvs------pevGVYSFMETVCIYGYSlsaYIPATVLCVV--------- 214
gi 82105831   160 ATaifTYAW--------LVPLALWGFLFWRnnkv------mslVTYSFMETVCTYGYSlaiYIPAVVLWIF--------- 216
gi 75042045   165 ATtiyAYAW--------LVPLALWGFLMWRnskv------mniVSYSFLEIVCVYGYSlfiYIPTAILWII--------- 221
gi 81883841   162 GItiyCYAW--------LVPLALWGFLRWRqgtr------ermGLYTFLETVCVYGYSlfvFIPTVVLWLI--------- 218
gi 82182100   161 AVtvfLYAW--------LVPLGVWGFLTWRqsve------rqiNGYTFLETVCVYGYSlfiYIPTSVLWTI--------- 217
gi 74633374   169 AAltySYTF--------LVPGALFLLLNYWdiga------tspHLSKLVNLIAVYGYSqcvWVLICAGNIILPVWLPVG- 233
gi 74625942   131 ASiiyGYTT--------IIAVLLWGILVWNk------------CNPKLLDCLCLYGYAnivWLPVSLATPPFGLLSTL-- 188
gi 74616668   170 AGliyGYTF--------VLPVALYLALRYFg-----------sESANLLECWALYGYSnliWIPVALISWS--------- 221
82_pfamImport  74 ASqfkKLLHSiwlfygyTFGVPFITMQVLN----RDehsernrSFKSVPELISVYGYAnliWIPVCVILNILDMSKrlrt 149
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 121724216  123 --LiFIPIYILVSLWklVINTLAVHSEYELGYGRSFLAAYGIIILIIT 168
gi 82179633   215 --------PHETFRWilILVAMSLSSLVLLLAFWPHIQRD--NKVVVI 252
gi 82105831   217 --------PYEWLKWcsIVVALCLSGSVLVMTFWPAVRDD--HPKIIV 254
gi 75042045   222 --------PQKAVRWilVMIALGISGSVLAMTFWPAVRED-NRRVALA 260
gi 81883841   219 --------PVQWLQWlfGALALALSAAGLVFTLWPVVRED-TRLVAAA 257
gi 82182100   218 --------PFNWLQWllIVVAMVISGSVLVITFWPAVRDD-TKLTAFA 256
gi 74633374   234 --F-----WINLVGWvlTTVGFLSSGWFLLKALYFPVKQNSPHLHLRV 274
gi 74625942   189 --------ASHIVKYvlTGIGLLISIVFLTRNLYPICQQA-GSNLCKL 227
gi 74616668   222 --------PITILNWvfVGVGFGVSVAFLLRNLYPVLSAT-DRQTSKV 260
82_pfamImport 150 vqaiQWAIVALGWAQssYFLNSQISSNNNTE----------TQSNGKF 187
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