6EM3


Conserved Protein Domain Family
Mak16

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pfam04874: Mak16 
Mak16 protein C-terminal region
The precise function of this eukaryotic protein family is unknown. The yeast orthologues have been implicated in cell cycle progression and biogenesis of 60S ribosomal subunits. The Schistosoma mansoni Mak16 has been shown to target protein transport to the nucleolus.
Statistics
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Aligned: 140 rows
Threshold Bit Score: 54.5517
Threshold Setting Gi: 0
Created: 6-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6EM3_3   138 APKVKRREQNRERKALVAAKIEKAIEKELMDRLKSGAY-G-DkPLNV---------DEKVWKKIMGqMe----------- 195 Saccharomyces cerev...
EGF84351 132 KKKVERREARREAKAEAAARLDMSIEKELLDRLRKGVY-GsDgIINE---------SQEAFTKALDeIe----------- 190 Batrachochytrium de...
EEZ98340 137 QRNIERREKIRERKALIAARIEKGVEKTLVERLKKGVY-Q-D-LYNI---------PQTAFEDAL--------------- 189 red flour beetle
Q4YB75   138 KKKTERRNKIREGKALKAANILNTVETELINRLNTGVY-G-N-LYKFltpkkkvknKESELTKIFSqIevnnmgkkkkkh 214 Plasmodium berghei
CDI82996 138 KKKTERREAAREKKALVAAHIEDVIEDELLKRLHQGVY-G-D-LYNE--------------------------------- 181 Eimeria acervulina
ESS34463 138 KQKTERREKAREKKAEVAAHLEDVIESELLKRLQQGVY-G-T-LYNF---------ESEKTAEA---------------- 189 Toxoplasma gondii VEG
EGD76264 139 NKKVERREARRELKALRAAHINKVIEKELLDRLKDGTYeG---VYNF---------PENAFNSALDkEg----------- 195 Salpingoeca rosetta
GAA27323 137 NRKLERREARREKKALRVARVERTVEQKLLERLRASTS-SkE-IYNI---------DQSAFEKAL--------------- 190 Clonorchis sinensis
CDS33397 119 NKKSERRELRREEKALRVAKLSRTVENELLERLRAATS-SkE-IYNI---------DQSAFKKAL--------------- 172 Hymenolepis microstoma
CDS40710 137 NKKSERRELRREEKALRVAKLSRTVENELLERLRAATS-SkE-IYNI---------DQSAFEKAL--------------- 190 Echinococcus multil...
6EM3_3   196 eENSqDEEEDWDEEeesddge--veyvaddGEGEYV--------------DVDD----LE 235 Saccharomyces cerevisiae S288C
EGF84351 191 ---EmHEQDEDELEde------------deEEEEFVsdm--------sedDVAD----LE 223 Batrachochytrium dendrobatidis JAM81
EEZ98340 190 -RENeVESETEETEkeme--------iegeDEGEFVpadt------ddesENEVdsdsgq 234 red flour beetle
Q4YB75   215 lDEEmEEIEEEDDDgd--------------------------------edETDDdgdedd 242 Plasmodium berghei
CDI82996 182 -HRLtKETTQEEKEtpevtt----akaaetGAIRFEaaaet----deeefASSD----FE 228 Eimeria acervulina
ESS34463 190 -EADqEEEEVKQDKaekrgvvafeeedeeeELSEYSesegsedfdfdesdEEED----IE 244 Toxoplasma gondii VEG
EGD76264 196 -EADeEPEDMDEEDeedeee----kqadpmAADEFVaeyee-----deedETKD----ME 241 Salpingoeca rosetta
GAA27323 191 -ETEeITDDEFEAEseeee------mmeddEEVVYTsase-------eeeEIEDlaqeee 236 Clonorchis sinensis
CDS33397 173 -ETEeLNEEVEEEDvsed---------egeEEVVYTsgse------leetDIEDlevpev 216 Hymenolepis microstoma
CDS40710 191 -EIEeLGEPKEKEE-----------------EVIYTsasel-----deeeDLEDlgviQE 227 Echinococcus multilocularis
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