3LLI,3GWL


Conserved Protein Domain Family
Evr1_Alr

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pfam04777: Evr1_Alr 
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Erv1 / Alr family
Biogenesis of Fe/S clusters involves a number of essential mitochondrial proteins. Erv1p of Saccharomyces cerevisiae mitochondria is required for the maturation of Fe/S proteins in the cytosol. The ALR (augmenter of liver regeneration) represents a mammalian orthologue of yeast Erv1p. Both Erv1p and full-length ALR are located in the mitochondrial intermembrane an d it thought to operate downstream of the mitochondrial ABC transporter.
Statistics
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PSSM-Id: 335893
View PSSM: pfam04777
Aligned: 336 rows
Threshold Bit Score: 58.0223
Threshold Setting Gi: 358331934
Created: 21-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3LLI_A       120 CSLWVLFHFLTVQAA-RQNVDHS----------QEAA----KAkevlpaIRGYVHYFFGCRDCASHFEQm----AAASMh 180 human
Q9VD62       412 CSLWTLFHYFTVLAAqMk---------------VYPPssvtIG------LYGLAKFFYDCKDGSMYFVK-----LAKRMn 465 fruit fly
Q8IMY4       424 CSLWVLFHYLSVESKk------------------LKPksvlLV------FLGYVRFFMNCKECDMKISE-----FKKLRp 474 fruit fly
XP_001780133 202 CGLWLLLHSLTVRVQeF------------------EAtfakLA------IEAFVDDFYKCDHCRDHFRNattrsQASSQ- 256 Physcomitrella ...
XP_002140597 401 CGVWILFHIWTVAVLhGAKTQINtknh--ylgpAITPqqvlNS------IKETVDNFFICKSCRDHFIS-----MFEHNe 467 Cryptosporidium...
XP_002778493 282 CGLWQLLHHLTLGVDrPYNGQKHqnd----ltgDRTGlaamTG------IKAIVSQYFACEECRRHFVE-----DYDKCl 346 Perkinsus marin...
XP_002286843 164 CGLWQLFHVISVGVVeYnmh-----------nePIPTrhasET------LRNYILHFFQCDVCRMHFLN-----QYDSCe 221 Thalassiosira p...
XP_002965433 292 CGLWLLFHALSVRV-------EDs-----------ESktaiQT------IRDFIASFFNCEDCRDHFLT-----MSTSAa 342 Selaginella moe...
XP_002951917 315 CGLWQMLHTMALRL-------PDlp------gaVGPAqsmmTF------LTLFNTHFFLCEPCQKHFGR-----ILSSPe 370 Volvox carteri ...
XP_002177501 591 CGFWKLLHVMTVGVAeHRGGKNLvatglrrdirVFAPmeaaDT------LREYMAHFFSCTECSKHFLV-----QYDQCd 659 Phaeodactylum t...
3LLI_A       181 r-----------------vGSPN---AAVLWLWSSHNRVNARLAGaPSe----DPQ---FP-KVQW 218 human
Q9VD62       466 ia---------------kvRTHD---EEILWLWEAHNEVNEKLAg--------DASgdpRFpKVQF 505 fruit fly
Q8IMY4       475 ia---------------nvTNDD---EQILWLWEAHNYVNKQLAg--------DSTedpKFpKIQF 514 fruit fly
XP_001780133 257 -------------------ISKR---DLVLWLWRIHNMITEVVAs-------eEHKtegNSsKL-W 292 Physcomitrella patens
XP_002140597 468 cdrlilvppenidnypikiEDAT---GLVFWLFRVHNAITTRVA---------IEStyrSIeQKQF 521 Cryptosporidium muris RN66
XP_002778493 347 ygrc----------vdgdsPTRE---ETVMWLWRFHNAVNGRVFa--------HRSpggDVrKAQW 391 Perkinsus marinus ATCC 50983
XP_002286843 222 ldvchr-------lsdkpsTSEHewrEFPMWLWETHNTVNDRLLr-------dRFFqngEPkANEW 273 Thalassiosira pseudonana CCMP...
XP_002965433 343 d----------------siNSRR---DLVLWFWRAHNQVNKRVGD-AEa---eSKTgdpKFpKQQW 385 Selaginella moellendorffii
XP_002951917 371 aa---------------avTDRR---ALALWLWRVHNEVNERLHG-IEtryghSTTgdpEFpKEQW 417 Volvox carteri f. nagariensis
XP_002177501 660 mnrrcgr-----latdahdATDSdwkELAKWLWEFHNDVSVHVLN-ER-----TDNkrkQMqQRTW 714 Phaeodactylum tricornutum CCA...
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