5ME0


Conserved Protein Domain Family
IF2_N

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pfam04760: IF2_N 
Click on image for an interactive view with Cn3D
Translation initiation factor IF-2, N-terminal region
This conserved feature at the N-terminus of bacterial translation initiation factor IF2 has recently had its structure solved. It shows structural similarity to the tRNA anticodon Stem Contact Fold domains of the methionyl-tRNA and glutaminyl-tRNA synthetases, and a similar fold is also found in the B5 domain of the phenylalanine-tRNA synthetase.
Statistics
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PSSM-Id: 335887
View PSSM: pfam04760
Aligned: 102 rows
Threshold Bit Score: 31.2693
Threshold Setting Gi: 148292005
Created: 25-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5ME0_W          1 MTDVTIKTLAAERQTSVERLVQQFaDAGIR-KSADDSVSAQEKQTLIDHLNQK 52   Escherichia coli BW2952
P25038         63 pNYISVNKLANLLNCRVERLIKDLtALGFEnITTTYILSKEYVELILQEYNFa 115  Saccharomyces cerevisiae S288c
O59683         93 PAVLSVASFANLLQIPTRRILRDLnRLGIKdVFPEYLITYEYSSLLAEEYGFD 145  Schizosaccharomyces pombe 972h-
Q2GQL9        349 PEFISVSNLAIALGQKIDVFVSQLeELGFEeVSKDNILTGETAALVAQEYGFE 401  Chaetomium globosum CBS 148.51
Q6MTQ0         40 TEPLSVIEFATKINKPLTAILKHYfNQGLL-LNQNTLLTEEQMGELCLEFGFD 91   Mycoplasma mycoides subsp. mycoides SC s...
Q6KID8         34 TGPMTINEFSKKIKKQAKDVILHFfKQGKM-YNANQIINEEEIAELCLEFDYE 85   Mycoplasma mobile 163K
A7I3V0        334 PKEIRLYEFAEKIKKQPSEIISKLfALGLM-TTKNDFLDEDAIEILGAEFDID 385  Campylobacter hominis ATCC BAA-381
XP_001416631  427 TDGMAIEDLTELLATTQAQIIKTLfMKGIA-VQMGQLLDKEAVIAVAEDMEVE 478  Ostreococcus lucimarinus CCE9901
WP_011949850   32 TNRTSLGEFAEKIKMNANDLIKRFlLRGKF-YQINHILEEEEIAEICMEKGLD 83   Mycoplasma agalactiae
XP_001540035  237 PEFITVGNLADVLGVRPADFLSRLaDFGFEeATYSHILDAETAGLIASEFNFT 289  Ajellomyces capsulatus NAm1
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