5ME0


Conserved Protein Domain Family
IF2_N

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pfam04760: IF2_N 
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Translation initiation factor IF-2, N-terminal region
This conserved feature at the N-terminus of bacterial translation initiation factor IF2 has recently had its structure solved. It shows structural similarity to the tRNA anticodon Stem Contact Fold domains of the methionyl-tRNA and glutaminyl-tRNA synthetases, and a similar fold is also found in the B5 domain of the phenylalanine-tRNA synthetase.
Statistics
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PSSM-Id: 335887
View PSSM: pfam04760
Aligned: 102 rows
Threshold Bit Score: 31.2693
Threshold Setting Gi: 500502572
Created: 25-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
5ME0_W          1 MTDVTIKTLAAERQTSVERLVQQFaDAGIR-KSADDSVSAQEKQTLIDHLNQK 52
gi 2506776     63 pNYISVNKLANLLNCRVERLIKDLtALGFEnITTTYILSKEYVELILQEYNFa 115
gi 6016315     93 PAVLSVASFANLLQIPTRRILRDLnRLGIKdVFPEYLITYEYSSLLAEEYGFD 145
gi 121927506  349 PEFISVSNLAIALGQKIDVFVSQLeELGFEeVSKDNILTGETAALVAQEYGFE 401
gi 81829398    40 TEPLSVIEFATKINKPLTAILKHYfNQGLL-LNQNTLLTEEQMGELCLEFGFD 91
gi 81828484    34 TGPMTINEFSKKIKKQAKDVILHFfKQGKM-YNANQIINEEEIAELCLEFDYE 85
gi 189028305  334 PKEIRLYEFAEKIKKQPSEIISKLfALGLM-TTKNDFLDEDAIEILGAEFDID 385
gi 145344213  427 TDGMAIEDLTELLATTQAQIIKTLfMKGIA-VQMGQLLDKEAVIAVAEDMEVE 478
gi 500502572   32 TNRTSLGEFAEKIKMNANDLIKRFlLRGKF-YQINHILEEEEIAEICMEKGLD 83
gi 154278443  237 PEFITVGNLADVLGVRPADFLSRLaDFGFEeATYSHILDAETAGLIASEFNFT 289
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