3GDE,1VS0


Conserved Protein Domain Family
DNA_ligase_A_C

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pfam04679: DNA_ligase_A_C 
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ATP dependent DNA ligase C terminal region
This region is found in many but not all ATP-dependent DNA ligase enzymes (EC:6.5.1.1). It is thought to constitute part of the catalytic core of ATP dependent DNA ligase.
Statistics
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PSSM-Id: 309703
View PSSM: pfam04679
Aligned: 145 rows
Threshold Bit Score: 42.9636
Threshold Setting Gi: 81968711
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3GDE_A        442 RSHWLSSFELA----CLDp----vTGK--------LLKVgRVATGFTEEDLEELTEMFR------PLIVSqqGKKV---- 495
gi 122011646  510 EFDRITHFLMGlaqkIDKnq--ptNSV--------ILPFvKVGTGFTDNELSTIRNKLRn----hWIKKQ--KPNYipqn 573
gi 121979902  564 WTDHITHYLVA----VAK------KIDlqnpsnsiLVPFaKVGAGFTARDYADIKARMRdqwvrtNHSNK--TPSFiiqn 631
gi 395398610  487 QSGKINSFLCGlr-mDYTpk--dhSEK--------FQSFvRVGGGFTYFDRDIIRKETEgk--wlPWSSD--ALEYmela 551
gi 122163062  451 RGGEVAQFLVGlavpSDDns---yPKR--------FLSFcRVGTGLSDEELDALVTKLKphfrknEYPKK--PPRFyevt 517
gi 74840198   458 RRTYVNAFLVG----VAArt--tpRPE--------YLSVaKVSMGLGTLEWQQLNQTLRphwrtgPVDGG--DGGAvvqc 521
gi 74871650   484 KRTFVDSFLLG----VLQpappgsSNRp------eVFSIgVVAN--NTKQRGVLNHTLKph--whDVVNE--PPPLwfhy 547
gi 121935152  545 RGGAHSSFLCA----LLLnkdakpGDAdye---kcWSFF-KVGGGFSREDYAAIRGRTEgk--wkDWDPR--RPPPiiel 612
gi 156615336  469 RQGMVSHFLCA----VAVps--drRGEkp----sqFYSLcKVGSGYTMNELDELGQQLKphwqpfNQAKP--PKSVcftp 536
gi 156739291  481 RSGMLSHFLCA----VAEvp--spGEKpt-----vFHTLcRIGSGYTLKELYDLGVKLAkh--wkVYNKN--NPPAailc 545
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
3GDE_A        496 -------------EFI--PKYVF---------EVAYQEIQKSPkyesgyALRFPRFVRLRDDK 534
gi 122011646  574 wnpg---vndrpdvYInnPAHSIi-------fEVKAAEITKSNtfptdyTLRFPRCYKTRMDK 626
gi 121979902  632 wkpg---ekdkpdaYIlsPQNSLi-------lEIRATEIIQSSqyptnyTLRFPRFEKFRRDK 684
gi 395398610  552 gtkq---dfekpdmWIh-PKDSLv-------lQIKAAEVVVSNrfktnyTLRFPRLEKVRLDR 603
gi 122163062  518 nh-----skerpdVWIesPDKSViisitsdirTIKSEVFAAPY------SLRFPRIQRLRYDK 569
gi 74840198   522 g-------qtapdVWIa-PADSIt-------lQLRGSELVRSDsyaagyTIRFPRIVTVRPDK 569
gi 74871650   548 kpke---rsgcpdlWIe-PQNSVi-------lQVKAADLAPNGafftrkSLHFPRTEMKRDDK 599
gi 121935152  613 ggheqnrqherpdQWIh-PSDSVv-------lECKAASVEGSDkfrfnlTLRFPRFRMLRTDK 667
gi 156615336  537 gf------kekpdvWIe-PSKSKv-------vQIKAAEITPSEkyragfTLRFPRLECVRHDK 585
gi 156739291  546 g-------tekpeVYIe-PRNSVi-------lQVKAAEIVTSEmyktdcTLRFPRIERIREDK 593
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