3GDE,1VS0


Conserved Protein Domain Family
DNA_ligase_A_C

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pfam04679: DNA_ligase_A_C 
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ATP dependent DNA ligase C terminal region
This region is found in many but not all ATP-dependent DNA ligase enzymes (EC:6.5.1.1). It is thought to constitute part of the catalytic core of ATP dependent DNA ligase.
Statistics
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PSSM-Id: 309703
View PSSM: pfam04679
Aligned: 145 rows
Threshold Bit Score: 42.9636
Threshold Setting Gi: 81968711
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3GDE_A        442 RSHWLSSFELA----CLDp----vTGK--------LLKVgRVATGFTEEDLEELTEMFR------PLIVSqqGKKV---- 495  Archaeoglobus...
Q3SE76        510 EFDRITHFLMGlaqkIDKnq--ptNSV--------ILPFvKVGTGFTDNELSTIRNKLRn----hWIKKQ--KPNYipqn 573  Paramecium te...
Q23RI5        564 WTDHITHYLVA----VAK------KIDlqnpsnsiLVPFaKVGAGFTARDYADIKARMRdqwvrtNHSNK--TPSFiiqn 631  Tetrahymena t...
O74833        487 QSGKINSFLCGlr-mDYTpk--dhSEK--------FQSFvRVGGGFTYFDRDIIRKETEgk--wlPWSSD--ALEYmela 551  Schizosacchar...
Q01KE4        451 RGGEVAQFLVGlavpSDDns---yPKR--------FLSFcRVGTGLSDEELDALVTKLKphfrknEYPKK--PPRFyevt 517  rice
Q7QFQ8        458 RRTYVNAFLVG----VAArt--tpRPE--------YLSVaKVSMGLGTLEWQQLNQTLRphwrtgPVDGG--DGGAvvqc 521  Anopheles gam...
Q9VYA5        484 KRTFVDSFLLG----VLQpappgsSNRp------eVFSIgVVAN--NTKQRGVLNHTLKph--whDVVNE--PPPLwfhy 547  fruit fly
Q0UCI9        545 RGGAHSSFLCA----LLLnkdakpGDAdye---kcWSFF-KVGGGFSREDYAAIRGRTEgk--wkDWDPR--RPPPiiel 612  Parastagonosp...
XP_001647535  469 RQGMVSHFLCA----VAVps--drRGEkp----sqFYSLcKVGSGYTMNELDELGQQLKphwqpfNQAKP--PKSVcftp 536  starlet sea a...
NP_001096593  481 RSGMLSHFLCA----VAEvp--spGEKpt-----vFHTLcRIGSGYTLKELYDLGVKLAkh--wkVYNKN--NPPAailc 545  zebrafish
3GDE_A        496 -------------EFI--PKYVF---------EVAYQEIQKSPkyesgyALRFPRFVRLRDDK 534  Archaeoglobus fulgidus
Q3SE76        574 wnpg---vndrpdvYInnPAHSIi-------fEVKAAEITKSNtfptdyTLRFPRCYKTRMDK 626  Paramecium tetraurelia
Q23RI5        632 wkpg---ekdkpdaYIlsPQNSLi-------lEIRATEIIQSSqyptnyTLRFPRFEKFRRDK 684  Tetrahymena thermophila SB210
O74833        552 gtkq---dfekpdmWIh-PKDSLv-------lQIKAAEVVVSNrfktnyTLRFPRLEKVRLDR 603  Schizosaccharomyces pombe 972h-
Q01KE4        518 nh-----skerpdVWIesPDKSViisitsdirTIKSEVFAAPY------SLRFPRIQRLRYDK 569  rice
Q7QFQ8        522 g-------qtapdVWIa-PADSIt-------lQLRGSELVRSDsyaagyTIRFPRIVTVRPDK 569  Anopheles gambiae str. PEST
Q9VYA5        548 kpke---rsgcpdlWIe-PQNSVi-------lQVKAADLAPNGafftrkSLHFPRTEMKRDDK 599  fruit fly
Q0UCI9        613 ggheqnrqherpdQWIh-PSDSVv-------lECKAASVEGSDkfrfnlTLRFPRFRMLRTDK 667  Parastagonospora nodorum SN15
XP_001647535  537 gf------kekpdvWIe-PSKSKv-------vQIKAAEITPSEkyragfTLRFPRLECVRHDK 585  starlet sea anemone
NP_001096593  546 g-------tekpeVYIe-PRNSVi-------lQVKAAEIVTSEmyktdcTLRFPRIERIREDK 593  zebrafish
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