6OZG,3GA2


Conserved Protein Domain Family
Endonuclease_5

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pfam04493: Endonuclease_5 
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Endonuclease V
Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or that is damaged by a variety of agents.
Statistics
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PSSM-Id: 427979
Aligned: 141 rows
Threshold Bit Score: 169.94
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6OZG_B          21 NELRKKIKLTPYEGEP----EYVAGVDLSFpgkeEG--LAVIVVLEYPSFK-ILEVVSERG-EITFPYIPGLLAFRQG-- 90  Thermotoga ma...
Q10348          18 IELKGMLQLIPKFQSLne-iRYVVGLDISFdkssPKa-VSALVIYDLEQRM-IIYKDYLCIeKLEEDYVPGFLSFREI-- 92  Schizosacchar...
XP_001568876   162 STFARQLPAL----------TFVGGVDISFipgtNDg-VACLAILRYPSME-LVKTYLHRC-TLREPYVSGFLSFREI-- 226
EFA80646       301 lkmAASVVKTNSNNLKlsdlKYIGGVDISFaknnKIdaCASIVVIEYPSLK-VVYESYKMV-KLTQPYIAGYLAFREI-- 376
XP_004358966   333 ldktnrVKKLPNGQLn---iKYVAGSDISFakgnKIdaCASIVVMEYPSLK-VVYESYKMI-KLTQPYIAGYLAMREV-- 405
EAY07837        15 TEMVVQIDNTKHLDNV----RYVAGADLTVeddlM---VGCLVVIDMENIDtPVYSKCTVV-NVDVPYIPGLLCFREG-- 84 
A8A9B8          13 RKLSELVKEEDCFDPEa--vEAVGGLDVSYkgdvG---VSALSLIDYKTLR-PLKHYYVVA-RVPIPYVPGFLAFREA-- 83  Ignicoccus ho...
WP_015232175    25 ilFSKKINLNDFINIRdienKVIAAVDASYtkndLG--IGVAIAFEYPSYN-IIDCELIAR-KVCIPYIPGLLAFREMyl 100 Caldisphaera ...
jgi:Igag_1924   15 IELSKRVVIEEIDLNRv---DIIAGLDVSYrgniG---VATAIAYNIKKMK--EECSVSVGgKVEIPYIPGLLAFREA-- 84 
imbp:Hbut_1565  14 KRLSRRIVSSLKPMDTas-iRRIVGLDAAYskryGGvaIAALTTR---DGQ-LLTYSVALG-EPPLQYIPGLLAFREA-- 85 
6OZG_B          91 --PLFLKAWEKLRT----K---P-DVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLY--------G----TFK- 147 Thermotoga ma...
Q10348          93 --KWYLPLLNHIPHqf------riDIILVDGNGVLHPVGFGLACHLGVLLNLPVVGVAKNYLHcvglteslDahreTLKk 164 Schizosacchar...
XP_001568876   227 --QPVCELIDAVRAelleTqtlP-QVLVVDGNGVLHPRRCGLATHLGIVLDIPTIGCSKKMLRvdg--lgrDavetALAt 301
EFA80646       377 --PHLLPLWNDLKRn--aPylvP-QVMVLDGNGINHMRGLGAACHLGVMIDCPTIGVAKQLLVchg--vtnEliedQFNq 449
XP_004358966   406 --DHLVALWQSLKRt--hPqftP-DIMVVDGNGVNHMRGMGLACHLGILIDCPTLGVAKNLLVchg--iteEyldeQFDy 478
EAY07837        85 --PVVLQMLDEFNQantgI---KiDLIIVDGNGEWHTRGLGLASYVGLKSNIPACGVSKTFFYvgeg-cpqPkdvqKMAq 158
A8A9B8          84 --PLHLTLIKKVKG--------Y-DLLLVDGHGRTHPRGLGIASHVGVTSGVPTVGVAKRRLV--------G-------- 136 Ignicoccus ho...
WP_015232175   101 isTPLLKLLKKVK---------P-QVLFVDGHGYAHPRFAGIATHIGIVFDIPTIGIAKKKLV--------G-------- 154 Caldisphaera ...
jgi:Igag_1924   85 --PLMIKALIKLKE----EcieP-DILMVNGHGIAHPRRLGIASHLGVVMDMPSIGIAKSFLY--------G----YID- 144
imbp:Hbut_1565  86 --PLFYTALRLLDS--------NyDLVVVDGHGISHPRRAGIASHIGIAIAKPSIGVAKKKLY--------G----HEQi 143
6OZG_B         148 MPEDKRCSW-----SYLY-------DgeEIIGCVIRTKEGS---------APIFVSPGHLMDVESSKRLIKAFTLpGR-R 205 Thermotoga ma...
Q10348         165 HVLKKTTDH-----PILIhsi--dqSs-EILGAAVWTSSNSk--------RPVYVSIGNQMNLEQSIQLVQKCSS-SHsR 227 Schizosacchar...
XP_001568876   302 LSEAESSTSslpciVPLLgt----sLptQLYGYAVHNHLNSv-------kKCIYVSPGHCVGFAVATALVITML--RY-R 367
EFA80646       450 RGNSAT--------IEMRns----mNn-ELLGYAMKNVDS----------ENIYISPGHKMDAKLALEIAKATLN-NR-P 504
XP_004358966   479 ATLGEA--------VQMKsd----qTn-ELLGYCTYNNEN----------ERLYISPGHKIDAYTALQVYEQTTK-TH-N 533
EAY07837       159 DKCPEKGDY-----YVLDytts---ndrYIKCAVMRTTDSHp-------fNPIYVSSGHLCDLDSVVSVIKKLC--RF-R 220
A8A9B8         137 -EEERCGER-----ECLV-------HegKVVAYVIRRGK-----------QKLYVSVGHCVSLETAYQIVKRLTVr---R 189 Ignicoccus ho...
WP_015232175   155 --------------EEVV----------ENNELYLRFKDRLvskillinnKKIYVSPGNKISLENSFNITKLMIG-KF-N 208 Caldisphaera ...
jgi:Igag_1924  145 ----FIDGS-----KVII-------VdgRIVGYVVK--KNR---------NEIYVSAGHKIAPHQALKISLETWLdNH-R 196
imbp:Hbut_1565 144 VSEDCK--------PPCIagyvvdeDtgEKLAAIVRTGRSKk--------SRLYVSPGAYTDLDSATTIVLELLEaRKtP 207
6OZG_B         206 IPEPTRLAHI 215 Thermotoga maritima
Q10348         228 VPEPIRQADI 237 Schizosaccharomyces pombe 972h-
XP_001568876   368 IPEPIRAADL 377
EFA80646       505 IPEPTFQADK 514
XP_004358966   534 LPEPTYIADH 543
EAY07837       221 EPEPTRLADR 230
A8A9B8         190 LPEPIAWADR 199 Ignicoccus hospitalis KIN4/I
WP_015232175   209 LPIPIYLADK 218 Caldisphaera lagunensis
jgi:Igag_1924  197 FPEPIYLADM 206
imbp:Hbut_1565 208 LPAPTYHADR 217
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