Conserved Protein Domain Family
CITED

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pfam04487: CITED 
CITED
CITED, CBP/p300-interacting transactivator with ED-rich tail, are characterized by a conserved 32-amino acid sequence at the C-terminus. CITED proteins do not bind DNA directly and are thought to function as transcriptional co-activators.
Statistics
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PSSM-Id: 309576
View PSSM: pfam04487
Aligned: 18 rows
Threshold Bit Score: 195.396
Threshold Setting Gi: 597763123
Created: 19-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888137    1 MAEHIMMPMNHGsagg-------glhgYRMGMN---------G-----PSP-HGHQPSLRTLPNGQLMHYSrgpQnSMEV 58
gi 82185831     1 MADH-MMAMNHSrfqdgtn--glhhpaHRMGMgqfsn-------hhhhPQQ-----HTFNSL-MGEHMHYG---PgNINA 61
gi 82112902     1 MAEH-MMAMNHGrfpdgag-glhhhpaHRLGMgqfaa-------phhhQHQ-QQQPHAFSAL-MGDHIHYG---AgNMNA 66
gi 1033365762   1 MADH-MMAMNHGrfpdgtn-gmhhhpaHRMGMgqfpt-------hhhqQQQ-Q---HAFSAL-MSDHIHYG---GgNMSA 63
gi 731221565    1 MADH-MMAMNHGrfadgtn-glhhhpaHRMGMgqfps-------phhhQQQ-QPQ-HAFNAL-MGEHIHYG---AaNMNA 65
gi 973215960    1 MADR-MMSMNHGrfsesangihphhptRRMAMgqfsnplhhqqqqqppPQQ-QQQ-HGYNGL-MGEHLHYG---GgNVNS 73
gi 54400592     1 MVDR-MMAMNHGrfpdavn--ghqhsaRRMGMgqfs---------nalPQQqH-----YNVI-MGDHMHYA---GgNINA 59
gi 551488851    1 MGDHMMMSMNHSsagt-------glhgYRMGMN---------GglqagHQQ-HANQQGMRALPNGQMMHYGg-nQaSMEA 62
gi 432882833    1 MAEHMMIPMTHA---------------FRMGLN---------G-----GPQ-HNGQSGLRSLPNGQVMHYGrnhQnNMEA 50
gi 597759220    1 MADHMMMPMNHGsagg--------lhgYRMGMN---------G-----HPQ-HAGQPGLRAVPNGQMMHYSrgpQgSMEP 57
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888137   59 AMRQR-NAMNGI--MNSQVngqmsgghPHQMQQANMMYASPNq----Qpqghpqsqhh------------hmhpqnqhpQ 119
gi 82185831    62 NNSIR-HAIVTGn-VNGg--------hPNGSMAPASRFn----------------------------------------S 91
gi 82112902    67 SGGVR-HAMGPGg-VGGg--------hPAGSMPPPARFSg---------------------------------------S 97
gi 1033365762  64 NAGIRqHAMGPGn-VSGg--------hPPGTMPPTARFSn---------------------------------------S 95
gi 731221565   66 TSGIR-HAMGPGt-VNGg--------hPPSALAPAARFNn---------------------------------------S 96
gi 973215960   74 NHGVR-HSMGPGn-VTGv--------hPNSSLAPSARYs----------------------------------------S 103
gi 54400592    60 NNGIR-HSMATGnnINGg--------iPNGNLP--ARFn----------------------------------------S 88
gi 551488851   63 AIRQR-QGMVGGp-MNGQLnga--qmgHHQMTSGNMMYNgqpqqqqqhhhpqqqqqqhhmhpqqhqqqaphpqqqqqqqq 138
gi 432882833   51 AMRHR-PAMVGPggMGGPVngaamtnhHQQMMSGNMIYNGQSlqqqqqqqhhhhhmht------qqqqqqqqqqqgghpQ 123
gi 597759220   58 AMRQR-LGIGPM--MNGQVagqmgtghHPQMQTSGMMYGNQQqgahlQpqhhmhpqts------------qqhpqqqhpQ 122
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123888137  120 QYMGsgGLSASQ--QLMASMHLQKLNTPYHG-HP-----------LGPMNGHHMGNV--QHRMGPAQLAGMQm------- 176
gi 82185831    92 PFMG---PVPNQgaQLTASMQLQKLNNQYFThHPyphnh--yipeLHPA--NQINGTnqHFRDCNPKHSTGmpp------ 158
gi 82112902    98 QFMA--APVGSPggQLSASMQLQKLNNQYFShHPyphgh--yvpdLHPGG-HPLSGGgqHFRDCNPKHGGGGsglp---- 168
gi 1033365762  96 QFMA--PTVAPQagPLTASMQLQKLNNQYFShHPyphnh--ympdMHPAS-HQLNGAnqHFRDCNPKHSNTSgstssgav 170
gi 731221565   97 QFMG--PPVASQggSLPASMQLQKLNNQYFNhHPyphnh--ympdLHPAAGHQMNGTnqHFRDCNPKhsggsstpggnnm 172
gi 973215960  104 QYVG--PAVSTQg-QLAASMQLQKLNTQYYThHPhpshh-hymsdLHSSN-HQMNGTgqQFRDCNPKHSTSSmpp----- 173
gi 54400592    89 QFVG-------QgqQLAASMQLQKLNTPYYGhHThpshhhhymheLHPAS-HQLNGTgqQFRDSIAKQNTSGvpl----- 155
gi 551488851  139 qFMN--GGLTSQ--QLMASMHLQKLNTQYHG-HP-----------LGPMGGNHMGPTn-QYRMNPAQLASMQ-------- 193
gi 432882833  124 QYLH--GNLTSQ--QLMASMHLQKLNTQYHG-HP-----------LSSANGHHLPNGs-QYRMGQTQLPNMP-------- 178
gi 597759220  123 QYMSggGMSSSQ--QLMASMHLQKLNTQYHA-LP-----------IGPGSGHHMGNGa-QYRMVQGQLAGMQm------- 180
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 123888137  177 -----GMGGPaLGHNVMDIDLIDEEVLTSLVLELGLDRVQELPELFLGQNEFDFFSDFVCKQQPSTVSC 240
gi 82185831   159 --svsHVPAAmLPPSVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPNRVSC 225
gi 82112902   169 -pavpHVPAAmLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 236
gi 1033365762 171 ptsvpHVPAAmLPPNVIDTDFIDEEVLMSLVVEMGLDRIKELPELWLGQNEFDFMTDFVCKQQSSRVSC 239
gi 731221565  173 pasvaHVPAAmLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 241
gi 973215960  174 --pahHVPAAiLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 240
gi 54400592   156 --pghHMPAAmLPPNVIDTDFIDEEVLMSLVIEMGLDRIKELPELWLGQNEFDFMTDFVCKQQPSRVSC 222
gi 551488851  194 -----HMAGPaLALNGMDADMIDEDVLTSLVMELGLDRVQELPELFLGQNEFDFISDFVSKQQPSTVSC 257
gi 432882833  179 -----HIGGP-LGLNGMDMDLIDEEVLTSLVLELGLDRVQELPELFLGQNEFDFISDFVCKQQPSTVSC 241
gi 597759220  181 -----GMGGPaLALNVMDTDLIDEEVLTSLVLELGLDRVQELPELFLGQNEFDFFSDFVCKQQPSTVSC 244
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