Conserved Protein Domain Family
Terminase_3

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pfam04466: Terminase_3 
Phage terminase large subunit
Initiation of packaging of double-stranded viral DNA involves the specific interaction of the prohead with viral DNA in a process mediated by a phage-encoded terminase protein. The terminase enzymes are usually hetero-oligomers composed of a small and a large subunit. This region is found on the large subunit and possess an endonuclease and ATPase activity that require Mg2+ and a neutral or slightly basic reaction. This region is also found in bacterial sequences.
Statistics
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PSSM-Id: 335802
View PSSM: pfam04466
Aligned: 7 rows
Threshold Bit Score: 235.401
Threshold Setting Gi: 81507717
Created: 25-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P45916        18 QKFQFLVGGYGSSKSYHVALKIVLKLLRE---KRTALV-IREVYDTHRDSTFSLFDELVSDLKLDHIVRCVSSPMQI-RF 92  Bacillus subtil...
Q65PP9        28 HLTEVWYGGASSGKSHGVVQKVVLKSLQHwnvPRKVLW-LRKVDRTVKNSIFTDVTECLSGWNILQYCHVNRSDKTI-VL 105 Lactobacillus j...
P39786        19 QTYQFLVGGYGSSKSYHTALKIVLKLLKE---KRTALV-IREVFDTHRDSTFALFQEVIEELGLTKAVASLSSPLQL-RF 93  Bacillus subtil...
O50744        19 AEIFIYYSSRGTGKTYDIATVNLERKFSA---DGGDTLaIRKKKNKTTQSIHKEILELLSIYNLRKFFNISKAKIESkSL 95  Lyme disease sp...
Q8Y4X9        33 HNHIIAKGGRSSMKSSVISLKLVEKKMAN---PQSNMVcLRKVANTLYKSVYQQIKWALYEMGVADQFKFGKSPMEIiHK 109 Listeria monocy...
Q9A018        27 NFYRVVKGSRGSKKSKTTALNFIVRLLKY---PWANLLvIRRYSNTNKQSTYTDFKWACNQLKVTHLFKFNESLPEItVK 103 Streptococcus p...
WP_015874054   5 KRIKVYFGGRGGMKTVSFAKIALITASMH---KRRFLC-LREFMNSIEDSVHAVLQAEVETLGLQNRFRILNTYI---EG 77  Candidatus Hami...
P45916        93 SNGSR--IIFKGM-DKPAKLKSIN----NISLIWIEECSEVKYEG-FKELLGRLR----HPTLPLHMILSTN-PVGEDNW 159 Bacillus subtil...
Q65PP9       106 PNGAI--FLFQGM-DDPEKIKSIK----GLSDVVMEEASEFNHND-YTQLTLRLRe---PKHKQRQIFCMFN-PVSKLNW 173 Lactobacillus j...
P39786        94 HNGSR--IMFKGM-DNPAKLKSVH----NISLIWIEECSEVKYEG-FKELIGRLR----HPELKLHMICTTN-PVGTSNW 160 Bacillus subtil...
O50744        96 IFGKKraFVFEGG-HDTRDLKSYA----HFKDLWLEEANQFSADD-IEMLVPTMR------EQGGRIYMSSN-PVPKSHW 162 Lyme disease sp...
Q8Y4X9       110 EWGTG--FYFSGC-DDPAKLKSMKipvgYVSDLWFEELAEFSGVTdIDVVEDTFIredlPDGQEVTIYMSFNpPRNPYEW 186 Listeria monocy...
Q9A018       104 ATGQK--ILFRGL-DDELKITSITvdvgALCWAWFEEAYQIETEDkFSTVVESIRgsldAPDFFKQITVTFN-PWSERHW 179 Streptococcus p...
WP_015874054  78 INDSI--FKYGQLaRNIASIKSKH----DFDVAWVEEAETVSEKS-LDTLIPTIR------KPGSELWFSFN-PAEEDGA 143 Candidatus Hami...
P45916       160 TFKHFFkddrekrfvlDDKELYEkriivSNDTYYHHSTADDNL--FLPESYVQQLEELKE----YDPDLYRIARKGH 230 Bacillus subtilis ...
Q65PP9       174 TYQTWF----------DPSADYD-----RSRVAIHQSTYKDNR--FLDEDNIRTIEELKN----TNPAYYKIYTLGE 229 Lactobacillus john...
P39786       161 TYRHFFrderkkrfvlDDSELYEkrtivKGDTYYHHSTANDNL--FLPESYVKQLDGLKE----YDPDLYRIARKGR 231 Bacillus subtilis ...
O50744       163 LYKRYLsn-------qDN-----------PAVCIIKSTYRDNP--FLNGGDVQAWLEKQRlayhGNDIGFRIEVLGE 219 Lyme disease spiro...
Q8Y4X9       187 VNEYV-----------DSKRSD-------DDYLIHHTTYLDDEkgFLSKQIIKKIEKYKK----NDLDYYRWMYLGE 241 Listeria monocytog...
Q9A018       180 LKRVFF----------DEETKR-------ADTFSGTTTFRVNE--WLDDVDKRRYEDLYK----TNPRRARIVCDGE 233 Streptococcus pyog...
WP_015874054 144 VYKRFVk--------pYKAIIDKqgyyeDDDLYVGKVSYLDNP--WLPAELKNDAQKMKR----ENYKKWRHVYGGE 206 Candidatus Hamilto...
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