Conserved Protein Domain Family
HA2

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pfam04408: HA2 
Helicase associated domain (HA2)
This presumed domain is about 90 amino acid residues in length. It is found is a diverse set of RNA helicases. Its function is unknown, however it seems likely to be involved in nucleic acid binding.
Statistics
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PSSM-Id: 335775
View PSSM: pfam04408
Aligned: 428 rows
Threshold Bit Score: 39.2922
Threshold Setting Gi: 695415056
Created: 21-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A0BYG8        452 SLRQLYLIQAI-------------------------DED-GYITpMGYEMSRYPLEPSYAKALITSklM-E-CSSEMSAI 503  Paramecium te...
Q4X5F5        517 SAKMLFKIKAI-------------------------DVN-NNLTeLGRQISLLPLSPIYGNMLLSA--VsFnCVDEMATL 568  Plasmodium ch...
Q4YHR1        260 SAKMLFKIKAI-------------------------DVN-NNLTeLGKQLSLLPISPIYGNMLLAS--VsFnCIDEMATL 311  Plasmodium be...
XP_002258110  515 SAKVLFRINAI-------------------------DVE-NNLTdLGKKMCLLPLNPIYANMMLCS--VdFhCMDEVATI 566  Plasmodium kn...
XP_001614948  513 SAKVLFRINAI-------------------------DVH-NNLTeLGKKMCLLPLSPIYANMMLCS--VeLhCMDEVATI 564  Plasmodium vi...
XP_001894285  532 SMSLLRSLKAVecce-----------------------smlvLTqLGKKMQQLPVEPRLAKMVLDSvqY-D-LVSETAII 586  Brugia malayi
ERG86897     1095 SRAMLMSIKAIav---------------------neKTGfVELTaRGREMIRLPVQPMLAHMILESleL-D-LLPEMAAV 1151 pig roundworm
EPR78500      385 SLKFLLQICAItm----------------------kNNI-FEITkYGEELVKLPLDIKMGNFFLTSkkY-N-CAKHCALL 439  Spraguea loph...
XP_003092746  634 SISFLTQIGAFyrsas----------------dedlDKD-PEVTeLGKIMARLPLDPQLARMLIFGlaL-K-CLGPIVNL 694  Caenorhabditi...
XP_001895682  653 SFEFLEQIGAVfkcrqessqmshltdnsyfsnardrNGE-PDLTdLGRHIVQLPLCPQLARFLLFGicL-K-CLSPVLTL 729  Brugia malayi
A0BYG8        504 VAILstesiwqritrvdvdg--------------------------------------------------------yqkl 527  Paramecium te...
Q4X5F5        569 IALLncdsiflnfnfddefddadtnlatmaskgngknenr----------------nkdkskkededydelkindkhkii 632  Plasmodium ch...
Q4YHR1        312 IALLncdsiflnfnfydendgvdtnltttask--------------------------------nedndelkisdknkii 359  Plasmodium be...
XP_002258110  567 VAFLncesiflnynfyedfkimneesaggslacsarekrdnqdkgdvldkddatinaktdesfepaveedptisdrnkli 646  Plasmodium kn...
XP_001614948  565 VAFLncesiflnynfyddlkvlgedsagggaanvgganpdg---------------anpdganpddappdpplteknkli 629  Plasmodium vi...
XP_001894285  587 CASIhvgslfnrtnkqnnf----------------------------------------------------------ila 608  Brugia malayi
ERG86897     1152 CACIhigslfmhhledevghd-------------------------------------------------------krlm 1176 pig roundworm
EPR78500      440 ISVIsqenfnffe------------------------------------------------------------------- 452  Spraguea loph...
XP_003092746  695 VSVLackdpfvlpslenknk---------------------------------------------------------qen 717  Caenorhabditi...
XP_001895682  730 VATLshrdpfvlppsgereer-------------------------------------------------------nsam 754  Brugia malayi
A0BYG8        528 qetqtqhadpagDHLS 543  Paramecium tetraurelia
Q4X5F5        633 niarkklihpdgDHLT 648  Plasmodium chabaudi
Q4YHR1        360 sisrkklihpdgDHLT 375  Plasmodium berghei
XP_002258110  647 niarrklmhpdgDHLT 662  Plasmodium knowlesi strain H
XP_001614948  630 nvarrklmhpdgDHLT 645  Plasmodium vivax Sal-1
XP_001894285  609 dqkklsfcedsgDPMT 624  Brugia malayi
ERG86897     1177 dqvlmsfydetgDPIS 1192 pig roundworm
EPR78500      453 ---dlknkknkdDILY 465  Spraguea lophii 42_110
XP_003092746  718 kkasfsaaqdfsDHLL 733  Caenorhabditis remanei
XP_001895682  755 mardifagfdysDHMT 770  Brugia malayi
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